Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Patrick A. Alford"'
Autor:
Bayardo I. Garay, Sophie Givens, Phablo Abreu, Man Liu, Doğacan Yücel, June Baik, Noah Stanis, Taylor M. Rothermel, Alessandro Magli, Juan E. Abrahante, Natalya A. Goloviznina, Hossam A.N. Soliman, Neha R. Dhoke, Michael Kyba, Patrick W. Alford, Samuel C. Dudley, Jr., Jop H. van Berlo, Brenda Ogle, Rita R.C. Perlingeiro
Publikováno v:
Stem Cell Reports, Vol 18, Iss 1, Pp 411- (2023)
Externí odkaz:
https://doaj.org/article/856a9044cd8d4fe1abc33aecc5500cd0
Autor:
Erdem D. Tabdanov, Vikram V. Puram, Zaw Win, Ashab Alamgir, Patrick W. Alford, Paolo P. Provenzano
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Invasive cells respond to contact guidance cues during migration. Here, using micro- and nanopatterning with different ligands and varying stiffness, the authors find that cells can make cellular protrusions through both contractility-dependent and c
Externí odkaz:
https://doaj.org/article/0089919579e3475c95e212fc5fe23d0a
Autor:
Bayardo I. Garay, Sophie Givens, Phablo Abreu, Man Liu, Doğacan Yücel, June Baik, Noah Stanis, Taylor M. Rothermel, Alessandro Magli, Juan E. Abrahante, Natalya A. Goloviznina, Hossam A.N. Soliman, Neha R. Dhoke, Michael Kyba, Patrick W. Alford, Samuel C. Dudley, Jop H. van Berlo, Brenda Ogle, Rita R.C. Perlingeiro
Publikováno v:
Stem Cell Reports. 17:2005-2022
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) provide great opportunities for mechanistic dissection of human cardiac pathophysiology; however, hiPSC-CMs remain immature relative to the adult heart. To identify novel signalin
Autor:
Arja Ray, Oscar Lee, Zaw Win, Rachel M. Edwards, Patrick W. Alford, Deok-Ho Kim, Paolo P. Provenzano
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Contact guidance on aligned substrates leads to directed cell migration through a poorly defined mechanism. Here the authors show that alignment of adhesion structures and F-actin generates anisotropic traction stress to drive directional migration,
Externí odkaz:
https://doaj.org/article/95889ff4ba5747cf995513288d87a844
Autor:
Aynsley M Smith, Patrick A Alford, Mark Aubry, Brian Benson, Amanda Black, Alison Brooks, Charles Burke, Ryan D’Arcy, David Dodick, Michael Eaves, Chad Eickhoff, Kristen Erredge, Kyle Farrell, Jonathon Finnoff, Douglas D. Fraser, Christopher Giza, Richard M Greenwald, Matthew Hanzel, Blaine Hoshizaki, John Huston, Janelle Jorgenson, Michael Joyner, David Krause, Nicole LaVoi, Matthew Leaf, John Leddy, Jordan Leopold, Kevin Margarucci, Susan Margulies, Jason Mihalik, Thayne Munce, Anna Oeur, Shjon Podein, Cara Prideaux, William O Roberts, Francis Shen, David Soma, Mark Tabrum, Michael B Stuart, Jennifer Wethe, James R Whitehead, Diane Wiese-Bjornstal, Michael J Stuart
Publikováno v:
Exercise Medicine, Vol 3 (2019)
Objectives The Ice Hockey Summit III provided updated scientific evidence on concussions in hockey to inform these five objectives: (1) describe sport related concussion (SRC) epidemiology, (2) classify prevention strategies, (3) define objective, di
Externí odkaz:
https://doaj.org/article/e9b78d89498049d4803b38c7bcf3ee10
Autor:
Elizabeth D. Shih, Colleen M. Witzenburg, Victor H. Barocas, Andrew W. Grande, Paolo P. Provenzano, Patrick W. Alford
Publikováno v:
Journal of Vascular Research. 59:34-42
Accurately assessing the complex tissue mechanics of cerebral aneurysms (CAs) is critical for elucidating how CAs grow and whether that growth will lead to rupture. The factors that have been implicated in CA progression – blood flow dynamics, immu
Autor:
Casey A. Chitwood, Elizabeth D. Shih, Omid Amili, Anthony S. Larson, Brenda M. Ogle, Patrick W. Alford, Andrew W. Grande
Publikováno v:
Neurosurgery clinics of North America. 33(4)
Predicting rupture risk in intracranial aneurysms is among one of the most critical questions in vascular surgery. The processes that govern an aneurysm growth are multifaceted and complex, but may be summarized into three components: hemodynamics, b
Autor:
Matthew Wheelwright, Zaw Win, Jennifer L Mikkila, Kamilah Y Amen, Patrick W Alford, Joseph M Metzger
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0194909 (2018)
Recent advances have made it possible to readily derive cardiac myocytes from human induced pluripotent stem cells (hiPSC-CMs). HiPSC-CMs represent a valuable new experimental model for studying human cardiac muscle physiology and disease. Many labor
Externí odkaz:
https://doaj.org/article/caf9cb36c65b4daba1edc969b79984a8
Publikováno v:
Biophys J
Chronic traumatic encephalopathy is a neurodegenerative disease associated with repeated traumatic brain injury (TBI). Chronic traumatic encephalopathy is a tauopathy, in which cognitive decline is accompanied by the accumulation of neurofibrillary t