The importance of selecting the appropriate reference genes for quantitative real time PCR as illustrated using colon cancer cells and tissue [version 1; referees: 2 approved]

Autor: Catríona M Dowling, Dara Walsh, John C Coffey, Patrick A Kiely

Publikováno v: F1000Research, Vol 5 (2016)

Quantitative real-time reverse-transcription polymerase chain reaction (RT-qPCR) remains the most sensitive technique for nucleic acid quantification. Its popularity is reflected in the remarkable number of publications reporting RT-qPCR data. Carefu

Externí odkaz: https://doaj.org/article/aa02cd5caa734211871f789966762e0c

Promoting cell proliferation using water dispersible germanium nanowires.

Autor: Michael Bezuidenhout, Pai Liu, Shalini Singh, Maeve Kiely, Kevin M Ryan, Patrick A Kiely

Publikováno v: PLoS ONE, Vol 9, Iss 9, p e108006 (2014)

Group IV Nanowires have strong potential for several biomedical applications. However, to date their use remains limited because many are synthesised using heavy metal seeds and functionalised using organic ligands to make the materials water dispers

Externí odkaz: https://doaj.org/article/467294bf06744684a4a3bd31ba2df65f

Pregnancy-specific glycoproteins bind integrin αIIbβ3 and inhibit the platelet-fibrinogen interaction.

Autor: Daniel K Shanley, Patrick A Kiely, Kalyan Golla, Seamus Allen, Kenneth Martin, Ronan T O'Riordan, Melanie Ball, John D Aplin, Bernhard B Singer, Noel Caplice, Niamh Moran, Tom Moore

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e57491 (2013)

Pregnancy-specific glycoproteins (PSGs) are immunoglobulin superfamily members encoded by multigene families in rodents and primates. In human pregnancy, PSGs are secreted by the syncytiotrophoblast, a fetal tissue, and reach a concentration of up to

Externí odkaz: https://doaj.org/article/36cc399900a842d09f227e777a1b78db

EULAR points to consider for therapeutic drug monitoring of biopharmaceuticals in inflammatory rheumatic and musculoskeletal diseases

Autor: Charlotte LM Krieckaert, Astrid van Tubergen, Johanna Elin Gehin, Borja Hernández-Breijo, Guillaume Le Mélédo, Alejandro Balsa, Peter Böhm, Sasa Cucnik, Ori Elkayam, Guro L Goll, Femke Hooijberg, Meghna Jani, Patrick DW Kiely, Neil McCarthy, Denis Mulleman, Victoria Navarro-Compán, Katherine Payne, Martin E Perry, Chamaida Plasencia-Rodriguez, Simon R Stones, Silje Watterdal Syversen, Annick de Vries, Katherine M Ward, Gertjan Wolbink, John D Isaacs

Publikováno v: Annals of the Rheumatic Diseases, 82(1), 65-73. BMJ Publishing Group
Annals of the rheumatic diseases, 82(1), 65-73. BMJ Publishing Group
Krieckaert, C L M, van Tubergen, A, Gehin, J E, Hernández-Breijo, B, le Mélédo, G, Balsa, A, Böhm, P, Cucnik, S, Elkayam, O, Goll, G L, Hooijberg, F, Jani, M, Kiely, P D W, McCarthy, N, Mulleman, D, Navarro-Compán, V, Payne, K, Perry, M E, Plasencia-Rodriguez, C, Stones, S R, Syversen, S W, de Vries, A, Ward, K M, Wolbink, G & Isaacs, J D 2022, ' EULAR points to consider for therapeutic drug monitoring of biopharmaceuticals in inflammatory rheumatic and musculoskeletal diseases ', Annals of the Rheumatic Diseases, vol. 82, no. 1, pp. 65-73 . https://doi.org/10.1136/annrheumdis-2022-222155

ObjectiveTo develop EULAR points-to-consider for therapeutic drug monitoring (TDM) of biopharmaceuticals in inflammatory rheumatic and musculoskeletal diseases (RMDs).MethodsThe points-to-consider were developed in accordance with EULAR standardised

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d0434b593d41d54250d4b1af8fec9e
https://doi.org/10.1136/annrheumdis-2022-222155

Parents’ information needs, treatment concerns, and psychological well-being when their child is diagnosed with adolescent idiopathic scoliosis: A systematic review

Autor: Gillian Motyer, Amanda Fitzgerald, Patrick J Kiely, Barbara Dooley

Publikováno v: Patient Education and Counseling. 104:1347-1355

Objective We systematically reviewed the experiences of parents who have a child with adolescent idiopathic scoliosis in order to understand their needs and concerns related to their child’s healthcare, and assist health professionals in supporting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d716cd7b8771e49f5c74ee9cf78e9f5f
https://doi.org/10.1016/j.pec.2020.11.023