Zobrazeno 1 - 10
of 381
pro vyhledávání: '"Patrick A, Ott"'
Autor:
David Liu, F Stephen Hodi, Rizwan Haq, Anita Giobbie-Hurder, Ann W Silk, Patrick A Ott, Tamara A Sussman, Elizabeth I Buchbinder, Anna K Maloney, Nikita Katukota, Miklos C Fogarasi, Megan Insco
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 8 (2024)
Background The combination of ipilimumab and nivolumab is a highly effective treatment for metastatic cutaneous melanoma. However, immune-related adverse events (irAEs) are common, often necessitating treatment interruption and the use of immunosuppr
Externí odkaz:
https://doaj.org/article/4034db27552e463dbba1b096428e2377
Autor:
Dirk Schadendorf, Ignacio Melero, Robert L Ferris, William Sharfman, Satyendra Suryawanshi, Jaclyn Neely, Fabrice Barlesi, Dung T Le, Jason J Luke, Patrick A Ott, Tina Cascone, Nikhil I Khushalani, Abanti Sanyal, Scott Ely, Manish R Sharma, Deanne Lathers, James L Holloway, Rasika Suryawanshi, Neil H Segal
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 3 (2024)
Background Resistance to immune checkpoint inhibitors and targeted treatments for cancer is common; thus, novel immunotherapy agents are needed. Urelumab is a monoclonal antibody agonist that binds to CD137 receptors expressed on T cells. Here, we re
Externí odkaz:
https://doaj.org/article/6310bf50e26a495fafc831096d8929f8
Autor:
Garrett S. Dunlap, Daniel DiToro, Joel Henderson, Sujal I. Shah, Mike Manos, Mariano Severgnini, Astrid Weins, Indira Guleria, Patrick A. Ott, Naoka Murakami, Deepak A. Rao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Immune checkpoint inhibitors (ICI) may have unanticipated side effects in transplant recipients who subsequently develop tumors. Here the authors used single-cell sequencing to identify and characterize allogeneic reactive T cells that developed afte
Externí odkaz:
https://doaj.org/article/e991277fef0d4954afa3894a6cef86f7
Autor:
Jennifer E. Yeh, MD, PhD, Marilyn T. Wan, MBChB, Allireza Alloo, MD, Nageatte Ibrahim, MD, Ivan Buzurovic, PhD, Jeffrey M. Cohen, MD, Patrick A. Ott, MD, PhD, Alvaro C. Laga, MD, Phillip M. Devlin, MD, Jennifer Y. Lin, MD
Publikováno v:
JAAD Case Reports, Vol 31, Iss , Pp 62-65 (2023)
Externí odkaz:
https://doaj.org/article/5e8a55193c0840489d6aac0f60a3f38b
Autor:
Jennifer E. Yeh, MD, PhD, Marilyn T. Wan, MBChB, MPH, Allireza Alloo, MD, Nageatte Ibrahim, MD, Patrick A. Ott, MD, PhD, Elizabeth I. Buchbinder, MD, Jennifer Y. Lin, MD
Publikováno v:
JAAD Case Reports, Vol 27, Iss , Pp 162-166 (2022)
Externí odkaz:
https://doaj.org/article/61a899a064ef46b1bfe0e0024ac4aba0
Autor:
Toshihiko Doi, John A Thompson, Omid Hamid, Adi Diab, Siwen Hu-Lieskovan, Jeffrey Chou, Jeffrey S Wasser, Patrick A Ott, Jean-Philippe Spano, Willeke Ros, Alison Forgie, Wenjing Yang, Ferry A L M Eskens, Alberto A Chiappori, Eric Angevin, Naiyer A Rizvi, Cen Guo, Anthony B El-Khoueiry
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 10 (2022)
Background Ivuxolimab (PF-04518600) and utomilumab (PF-05082566) are humanized agonistic IgG2 monoclonal antibodies against OX40 and 4-1BB, respectively. This first-in-human, multicenter, open-label, phase I, dose-escalation/dose-expansion study expl
Externí odkaz:
https://doaj.org/article/ccd14bbe12da44b9bec3de265e3da2d8
Autor:
Ai-Tram N. Bui, Kevin Tyan, Anita Giobbie-Hurder, Isaac A. Klein, Michael P. Manos, Leyre Zubiri, Kerry Reynolds, Shilpa Grover, Gerald L. Weinhouse, Patrick A. Ott, Nicole R. LeBoeuf, Osama Rahma
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Pp 35-44 (2021)
Introduction: To evaluate the impact of Sars-Cov-2 infection on mortality and immune checkpoint inhibitor (ICI) toxicity in patients with cancer receiving ICIs compared to those not receiving ICIs. Methods: We conducted a retrospective matched cohort
Externí odkaz:
https://doaj.org/article/34234964abed47a0b6617ad080e21725
Autor:
Elizabeth I. Buchbinder, Jason L. Weirather, Michael Manos, Brian J. Quattrochi, Lynette M. Sholl, Ryan C. Brennick, Peter Bowling, Nancy Bailey, Lisa Magarace, Patrick A. Ott, Rizwan Haq, Benjamin Izar, Anita Giobbie‐Hurder, F. Stephen Hodi
Publikováno v:
Cancer Medicine, Vol 10, Iss 8, Pp 2627-2635 (2021)
Abstract Mucosal melanoma is a rare form of melanoma which arises from melanocytes in the mucosal membranes and can be effectively treated with immune checkpoint blockade (ICB). However, response rates in mucosal melanoma are lower than those observe
Externí odkaz:
https://doaj.org/article/24cb2e96d164402e9d316cff9ef36d9a
Autor:
Marieke J. Krimphove, Karl H. Tully, David F. Friedlander, Maya Marchese, Praful Ravi, Stuart R. Lipsitz, Kerry L. Kilbridge, Adam S. Kibel, Luis A. Kluth, Patrick A. Ott, Toni K. Choueiri, Quoc-Dien Trinh
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-11 (2019)
Abstract Background The introduction of immune checkpoint inhibitors has led to a survival benefit in patients with advanced melanoma; however data on the adoption of immunotherapy in the community are scarce. Methods Using the National Cancer Databa
Externí odkaz:
https://doaj.org/article/fe00c9dd3430424a9ffbabc79d12606b
Autor:
Mariano Severgnini, Rizwan Haq, Anita Giobbie-Hurder, Scott J Rodig, Patrick A Ott, Evisa Gjini, Ryan J Sullivan, Donald P Lawrence, Matthew Nazzaro, Kathleen L Pfaff, Jacquelyn O Wolff, Elizabeth I Buchbinder
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/209a1d9fbce1433f83f364f311d116e0