Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Patrick, Sips"'
Autor:
Dechamma Pandyanda Nanjappa, Hanna De Saffel, Krithika Kalladka, Srividya Arjuna, Nishith Babu, Kishan Prasad, Patrick Sips, Anirban Chakraborty
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Poly (A)-specific ribonuclease (PARN) is the most important 3′–5′exonuclease involved in the process of deadenylation, the removal of poly (A) tails of mRNAs. Although PARN is primarily known for its role in mRNA stability, recent stud
Externí odkaz:
https://doaj.org/article/6cff2d0e82e44d0a84036be836486cfe
Autor:
Lore Pottie, Wouter Van Gool, Michiel Vanhooydonck, Franz-Georg Hanisch, Geert Goeminne, Andreja Rajkovic, Paul Coucke, Patrick Sips, Bert Callewaert
Publikováno v:
PLoS Genetics, Vol 17, Iss 6, p e1009603 (2021)
The inability to maintain a strictly regulated endo(lyso)somal acidic pH through the proton-pumping action of the vacuolar-ATPases (v-ATPases) has been associated with various human diseases including heritable connective tissue disorders. Autosomal
Externí odkaz:
https://doaj.org/article/e7e591bf2c134b2397029f0d37644e88
Autor:
Felke Steijns, Nathalie Bracke, Marjolijn Renard, Julie De Backer, Patrick Sips, Nathan Debunne, Evelien Wynendaele, Frederick Verbeke, Bart De Spiegeleer, Laurence Campens
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Upregulation of the RAS-RAF-MEK-ERK-MAPK pathway is involved in the development of several human tumors, aortic aneurysms, atherosclerosis, and cardiomyopathy. Refametinib, a highly selective MEK-inhibitor, has already shown antineoplastic activity i
Externí odkaz:
https://doaj.org/article/3ef60489e3fc45979fff017a2792931f
Autor:
Eline Goossens, Loren Deblock, Lisa Caboor, Dietger Van den Eynden, Ivan Josipovic, Pablo Reyes Isaacura, Elizaveta Maksimova, Matthias Van Impe, Anne Bonnin, Pieter Cornillie, Matthieu Boone, Isabel Van Driessche, Ward De Spiegelaere, Jonathan De Roo, Patrick Sips, Klaartje De Buysser
Vascular corrosion casting is a method used to visualize the three dimensional anatomy and branching pattern of blood vessels, guiding insight into health and cardiovascular disease pathogenesis and progression. A polymer resin is injected in the vas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ef883a5e3018d9dbc0b6c3a7602f7ed
https://doi.org/10.26434/chemrxiv-2023-m7wql
https://doi.org/10.26434/chemrxiv-2023-m7wql
Autor:
Mao Wang, Patrick Sips, Ester Khin, Maxime Rotival, Ximing Sun, Rizwan Ahmed, Anissa Anindya Widjaja, Sebastian Schafer, Permeen Yusoff, Pervinder Kaur Choksi, Nicole Shi Jie Ko, Manvendra K. Singh, David Epstein, Yuguang Guan, Josef Houštěk, Tomas Mracek, Hana Nuskova, Brittney Mikell, Jessie Tan, Francesco Pesce, Frantisek Kolar, Leonardo Bottolo, Massimiliano Mancini, Norbert Hubner, Michal Pravenec, Enrico Petretto, Calum MacRae, Stuart A Cook
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Blood supply to the heart is crucial for cardiac function. Here, the authors show that the mitochondrial tryptophanyl-tRNA synthetase, WARS2, drives blood vessel generation in zebrafish and rats and that inhibition of Wars2 diminishes blood vessel gr
Externí odkaz:
https://doaj.org/article/550ec9cd37e7417c90bb6b8603a4479c
Autor:
Matthias Van Impe, Lisa Caboor, Violette Deleeuw, Margie Olbinado, Julie De Backer, Patrick Sips, Patrick Segers
Publikováno v:
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
Objective : The zebrafish is increasingly used as a small animal model for cardiovascular disease, including vascular disorders. Nevertheless, a comprehensive biomechanical understanding of the zebrafish cardiovascular circulation is still lacking an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b8d5b09663994eb0e3a663edce810f8
https://biblio.ugent.be/publication/01GY7JJXBA400KVSSP8Z3V5X17
https://biblio.ugent.be/publication/01GY7JJXBA400KVSSP8Z3V5X17
Autor:
Eline Goossens, Jonathan De Roo, Lisa Caboor, Olivia Aalling-Frederiksen, Dietger Van den Eynden, Pablo Reyes Isaacura, Ivan Josipovic, Loren Deblock, Ward De Spiegelaere, Kirsten M Ø Jensen, Matthieu N Boone, Isabel Van Driessche, Patrick Sips, Klaartje De Buysser, Pieter Cornillie
Publikováno v:
Proceedings of the MATSUS23 & Sustainable Technology Forum València (STECH23).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f89d0c3eaf8827a9a4cb2ffd55a99fd3
https://doi.org/10.29363/nanoge.matsus.2023.073
https://doi.org/10.29363/nanoge.matsus.2023.073
Autor:
Felke Steijns, Máté I. Tóth, Anthony Demolder, Lars E. Larsen, Jana Desloovere, Marjolijn Renard, Robrecht Raedt, Patrick Segers, Julie De Backer, Patrick Sips
Publikováno v:
Sensors, Vol 20, Iss 14, p 3867 (2020)
Ambulatory electrocardiography (AECG) is a primary diagnostic tool in patients with potential arrhythmic disorders. To study the pathophysiological mechanisms of arrhythmic disorders, mouse models are widely implemented. The use of a technique simila
Externí odkaz:
https://doaj.org/article/7a634f7cb2f94679a6bfbd72b4b05cc2
Autor:
Julie de Backer, Violette de Leeuw, Mathias Van Impe, Marine Vanhomwegen, Gerlinde Logghe, Margie Oblinado, Marco Stampanoni, Patrick Segers, Laura Muino Mosquera, Lynn Sakai, Patrick Sips
Publikováno v:
Cardiovascular Research. 118
Introduction Marfan syndrome (MFS) is caused by a defect in fibrillin-1, which binds TGF-beta via interaction with latent TGF-beta binding proteins (LTBPs). The role of TGF-beta in MFS is controversial. Objectives use dedicated mouse models for MFS,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eb227ea2a1bbee449e6748cd9cddbf1
https://doi.org/10.1093/cvr/cvac157.111
https://doi.org/10.1093/cvr/cvac157.111
Publikováno v:
Cardiovascular Research. 118
Introduction Marfan syndrome (MFS) is the most common type of fibrillinopathy with a high predisposition to develop TAAD. A thorough understanding of the underlying mechanisms is still lacking, indicating a particular need for more flexible in vivo m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57c6b6616e5027c1f380816d87b5b8e4
https://doi.org/10.1093/cvr/cvac157.112
https://doi.org/10.1093/cvr/cvac157.112