Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Patrick, O'Kane"'
Autor:
Ekaterina Chirikova, Robert J. McConnell, Patrick O’Kane, Vasilina Yauseyenka, Mark P. Little, Victor Minenko, Vladimir Drozdovitch, Ilya Veyalkin, Maureen Hatch, June M. Chan, Chiung-Yu Huang, Kiyohiko Mabuchi, Elizabeth K. Cahoon, Alexander Rozhko, Lydia B. Zablotska
Publikováno v:
Environmental Health, Vol 21, Iss 1, Pp 1-10 (2022)
Abstract Background While there is a robust literature on environmental exposure to iodine-131 (131I) in childhood and adolescence and the risk of thyroid cancer and benign nodules, little is known about its effects on thyroid volume. Methods To asse
Externí odkaz:
https://doaj.org/article/9b7587d80ff74592a911ac3f9fe2cdf8
Publikováno v:
Advanced Ultrasound in Diagnosis and Therapy, Vol 4, Iss 3, Pp 176-182 (2020)
Objective: This study evaluated the performance of automated machine-learning to diagnose non-alcoholic fatty liver disease (NAFLD) by ultrasound and compared these findings to radiologist performance.Methods: 96 patients with histologic (33) or prot
Externí odkaz:
https://doaj.org/article/89f2d4010f7a4cd39ebde7df615e1dbd
Autor:
Quezia Lacerda, Hebah Falatah, Ji-Bin Liu, Corinne E. Wessner, Brian Oeffinger, Ankit Rochani, Dennis B. Leeper, Flemming Forsberg, Joseph M. Curry, Gagan Kaushal, Scott W. Keith, Patrick O’Kane, Margaret A. Wheatley, John R. Eisenbrey
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1302 (2023)
Tumor hypoxia (oxygen deficiency) is a major contributor to radiotherapy resistance. Ultrasound-sensitive microbubbles containing oxygen have been explored as a mechanism for overcoming tumor hypoxia locally prior to radiotherapy. Previously, our gro
Externí odkaz:
https://doaj.org/article/1a19f6f3948d4cdd96820563b7ebdc10
Autor:
John R. Eisenbrey, Allison Tan, Patrick O'Kane, Kevin Anton, Lauren J Delaney, Jesse Civan, Flemming Forsberg, Priscilla Machado, Andrej Lyshchik, Colette M. Shaw, Ji-Bin Liu, Mohamed Tantawi, Corinne E. Wessner
Publikováno v:
Ultrasound Med Biol
Conventional cross-sectional imaging done shortly after radioembolization of hepatocellular carcinoma (HCC) does not reliably predict long-term response to treatment. This study evaluated whether quantitative contrast-enhanced ultrasound (CEUS) can p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9303bd11808cd77b9ca638191ff561b4
https://doi.org/10.1016/j.ultrasmedbio.2021.05.006
https://doi.org/10.1016/j.ultrasmedbio.2021.05.006
Autor:
Amanda R. Smolock, Kristen Bradigan, Allison Tan, Patrick O'Kane, Andrej Lyshchik, Mohamed Tantawi, Scott W. Keith, Warren R. Maley, Colette M. Shaw, Ji-Bin Liu, Flemming Forsberg, John R. Eisenbrey, Lauren J Delaney, Charles M. Intenzo, Kevin Anton, Corinne E. Wessner, Sriharsha Gummadi, Susan Shamimi-Noori, Jesse Civan
Publikováno v:
Radiology
BACKGROUND: US contrast agents are gas-filled microbubbles (MBs) that can be locally destroyed by using external US. Among other bioeffects, US-triggered MB destruction, also known as UTMD, has been shown to sensitize solid tumors to radiation in pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c12d685dc1ad61e29ceeca14af883a3
https://doi.org/10.1148/radiol.2020202321
https://doi.org/10.1148/radiol.2020202321
Autor:
Quezia, Lacerda, Ankit, Rochani, Brian, Oeffinger, Ji-Bin, Liu, Corinne E, Wessner, Aylin, Tahmasebi, Hebah, Falatah, Philip, Lee, Dennis B, Leeper, Flemming, Forsberg, Joseph, Curry, Scott W, Keith, Patrick, O'Kane, Gagan, Kaushal, Margaret A, Wheatley, John R, Eisenbrey
Publikováno v:
Int J Pharm
Prior work has shown that microbubble-assisted delivery of oxygen improves tumor oxygenation and radiosensitivity, albeit over a limited duration. Lonidamine (LND) has been investigated because of its ability to stimulate glycolysis, lactate producti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::730898a6298a784001eb928cfc3d65e0
https://doi.org/10.1016/j.ijpharm.2022.122072
https://doi.org/10.1016/j.ijpharm.2022.122072
Autor:
Jonathan Stem, Patrick O'Kane, Andrej Lyshchik, Corinne E. Wessner, Flemming Forsberg, Sriharsha Gummadi, Ji-Bin Liu, John R. Eisenbrey, Priscilla Machado, George Koenig
Publikováno v:
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in MedicineReferences. 41(4)
Background Small intestinal ischemia is a challenging diagnosis to make, even with the combination of imaging, laboratory analysis, and physical exam. This pilot study investigated the role of CEUS in evaluating small bowel wall vascularity in partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9be6483883909bf2a70f6afa901a1b0
https://pubmed.ncbi.nlm.nih.gov/34101877
https://pubmed.ncbi.nlm.nih.gov/34101877
Autor:
Patrick O'Kane, Flemming Forsberg, Gagan Kaushal, Margaret A. Wheatley, John R. Eisenbrey, Raj Patel, Brian E. Oeffinger, Quezia Lacerda, Ankit K. Rochani, Dennis B. Leeper
Publikováno v:
2020 IEEE International Ultrasonics Symposium (IUS).
Lonidamine (LND) has been widely explored due to its ability to target metabolic glycolysis and mitochondrial respiration in tumors [4]. However, clinical translation has stalled due to poor bioavailability after oral administration. In this study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::978e8790b6278c362bf09bf6ecaab921
https://doi.org/10.1109/ius46767.2020.9251788
https://doi.org/10.1109/ius46767.2020.9251788
Autor:
Rawan Shraim, John R. Eisenbrey, Brian E. Oeffinger, Lauren J. Jablonowski, Scott W. Keith, Maria Stanczak, Patrick O'Kane, Jingzhi Li, Ji-Bin Liu, Dennis B. Leeper, Margaret A. Wheatley, Flemming Forsberg
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 101:88-96
Much of the volume of solid tumors typically exists in a chronically hypoxic microenvironment that has been shown to result in both chemotherapy and radiation therapy resistance. The purpose of this study was to use localized microbubble delivery to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc993dcc50dbc40ebf6771e5e757e511
https://doi.org/10.1016/j.ijrobp.2018.01.042
https://doi.org/10.1016/j.ijrobp.2018.01.042
Autor:
Ilya Veyalkin, Robert J. McConnell, Lydia B. Zablotska, Maureen Hatch, Vasilina Yauseyenka, Victor Minenko, Mark P. Little, Elizabeth K. Cahoon, Vladimir Drozdovitch, Ekaterina Chirikova, Patrick O'Kane, Alexander Rozhko
Publikováno v:
Journal of the Endocrine Society, vol 5, iss Supplement_1
Journal of the Endocrine Society, vol 5, iss Suppl 1
Journal of the Endocrine Society
Journal of the Endocrine Society, vol 5, iss Suppl 1
Journal of the Endocrine Society
Author(s): Chirikova, Ekaterina; Cahoon, Elizabeth K; Rozhko, Alexander; Drozdovitch, Vladimir; Little, Mark P; McConnell, Robert J; Minenko, Victor; Veyalkin, Ilya; Yauseyenka, Vasilina; Hatch, Maureen; O’Kane, Patrick; Zablotska, Lydia B | Abstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be04591e324f29ede554b6249d4ffce1
https://doi.org/10.1210/jendso/bvab048.1748
https://doi.org/10.1210/jendso/bvab048.1748