Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Patrick, Lecine"'
Autor:
Djomangan Adama Ouattara, Lydie Remolue, Jérémie Becker, Magali Perret, Andrei Bunescu, Kristin Hennig, Emeline Biliaut, Annemanuelle Badin, Cesarino Giacomini, Frédéric Reynier, Christine Andreoni, Frédéric Béquet, Patrick Lecine, Karelle De Luca
Publikováno v:
Poultry Science, Vol 99, Iss 9, Pp 4360-4372 (2020)
The immunological immaturity of the innate immune system during the first-week post-hatch enables pathogens to infect chickens, leading to the death of the animals. Current preventive solutions to improve the resistance of chicks to infections includ
Externí odkaz:
https://doaj.org/article/dec5b0520346430f8d78a2ae5ad9b957
Autor:
Akul Singhania, Raman Verma, Christine M. Graham, Jo Lee, Trang Tran, Matthew Richardson, Patrick Lecine, Philippe Leissner, Matthew P. R. Berry, Robert J. Wilkinson, Karine Kaiser, Marc Rodrigue, Gerrit Woltmann, Pranabashis Haldar, Anne O’Garra
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Mass screening diagnostics for Mycobacterium tuberculosis exist, but criticisms exist regarding the sensitivity and specificity of these tools. Here the authors use RNA-Seq and a modular bioinformatics approach using data from their own cohorts and m
Externí odkaz:
https://doaj.org/article/f00dac82845249b8a6fa26d64cff3275
Autor:
Raphaële Thiébaut, Sophie Esmiol, Patrick Lecine, Batoul Mahfouz, Aurelie Hermant, Cendrine Nicoletti, Stephane Parnis, Julie Perroy, Jean-Paul Borg, Leigh Pascoe, Jean-Pierre Hugot, Vincent Ollendorff
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165420 (2016)
NOD2 contributes to the innate immune response and to the homeostasis of the intestinal mucosa. In response to its bacterial ligand, NOD2 interacts with RICK and activates the NF-κB and MAPK pathways, inducing gene transcription and synthesis of pro
Externí odkaz:
https://doaj.org/article/d104d6b8fb8349ca8fc5fa70f2f07371
Autor:
Anna Martirosyan, Camino Pérez-Gutierrez, Romain Banchereau, Hélène Dutartre, Patrick Lecine, Melissa Dullaers, Marielle Mello, Suzana Pinto Salcedo, Alexandre Muller, Lee Leserman, Yves Levy, Gerard Zurawski, Sandy Zurawski, Edgardo Moreno, Ignacio Moriyón, Eynav Klechevsky, Jacques Banchereau, Sangkon Oh, Jean-Pierre Gorvel
Publikováno v:
PLoS Pathogens, Vol 8, Iss 11, p e1002983 (2012)
Bacterial cyclic glucans are glucose polymers that concentrate within the periplasm of alpha-proteobacteria. These molecules are necessary to maintain the homeostasis of the cell envelope by contributing to the osmolarity of Gram negative bacteria. H
Externí odkaz:
https://doaj.org/article/ed1affcc153040f3a4afe99dbcf2e92d
Autor:
Christine M. Graham, Gerrit Woltmann, Anne O'Garra, Pranabashis Haldar, Akul Singhania, Trang Tran, Matthew Berry, Marc Rodrigue, Patrick Lecine, Philippe Leissner, Robert J. Wilkinson, Raman Verma, Matthew Richardson, Karine Kaiser, Jo Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Whole blood transcriptional signatures distinguishing active tuberculosis patients from asymptomatic latently infected individuals exist. Consensus has not been achieved regarding the optimal reduced gene sets as diagnostic biomarkers that also achie
Autor:
Julie, Milanini, Racha, Fayad, Mariagrazia, Partisani, Patrick, Lecine, Jean-Paul, Borg, Michel, Franco, Frédéric, Luton
Publikováno v:
Journal of cell science. 131(3)
A key step of epithelial morphogenesis is the creation of the lumen. Luminogenesis by hollowing proceeds through the fusion of apical vesicles at cell-cell contacts. The small nascent lumens grow through extension, coalescence and enlargement, coordi
Autor:
Ramesh A. Shivdasani, Sanjay Tiwari, Joseph E. Italiano, Heinz Schwer, Patrick Lecine, John H. Hartwig
Publikováno v:
Current Biology. 11:579-586
Background: Mammalian megakaryocytes release blood platelets through a remarkable process of cytoplasmic fragmentation and de novo assembly of a marginal microtubule band. Cell-specific components of this process include the divergent β-tubulin isof
Publikováno v:
The Journal of Cell Biology
Megakaryocytes release mature platelets in a complex process. Platelets are known to be released from intermediate structures, designated proplatelets, which are long, tubelike extensions of the megakaryocyte cytoplasm. We have resolved the ultrastru
Autor:
Jack Levin, Jin-Peng Peng, Georgiann R. Baker, Jean-Luc Villeval, Patrick Lecine, Samuel A. Burstein, Ramesh A. Shivdasani
Publikováno v:
Blood. 94:3037-3047
Expression of the p45 subunit of transcription factor NF-E2 is restricted to selected blood cell lineages, including megakaryocytes and developing erythrocytes. Mice lacking p45 NF-E2 show profound thrombocytopenia, resulting from a late arrest in me
Autor:
Patrick Lecine, Ramesh A. Shivdasani, Jean-luc Villeval, Yuhui Xu, Paresh Vyas, Bethany Swencki
Publikováno v:
Blood. 92:1608-1616
Mechanisms of platelet production and release by mammalian megakaryocytes are poorly understood. We used thrombocytopenic knockout mice to better understand these processes. Proplatelets are filamentous extensions of terminally differentiated megakar