Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Patrick, Lahni"'
Autor:
Mihir R. Atreya, Natalie Z. Cvijanovich, Julie C. Fitzgerald, Scott L. Weiss, Michael T. Bigham, Parag N. Jain, Adam J. Schwarz, Riad Lutfi, Jeffrey Nowak, Geoffrey L. Allen, Neal J. Thomas, Jocelyn R. Grunwell, Torrey Baines, Michael Quasney, Bereketeab Haileselassie, Matthew N. Alder, Patrick Lahni, Scarlett Ripberger, Adesuwa Ekunwe, Kyle R. Campbell, Keith R. Walley, Stephen W. Standage
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-12 (2023)
Abstract Background Sepsis is associated with significant mortality. Yet, there are no efficacious therapies beyond antibiotics. PCSK9 loss-of-function (LOF) and inhibition, through enhanced low-density lipoprotein receptor (LDLR) mediated endotoxin
Externí odkaz:
https://doaj.org/article/f5f9c595a1074237837d943ff4b74a9f
Autor:
Lauren Bodilly, Lauren Williamson, Patrick Lahni, Matthew N. Alder, David B. Haslam, Jennifer M. Kaplan
Publikováno v:
Innate Immunity, Vol 29 (2023)
Sepsis is a leading cause of mortality. Plasma cytokine levels may identify those at increased risk of mortality from sepsis. Our aim was to understand how obesity alters cytokine levels during early sepsis and its correlation with survival. Six-week
Externí odkaz:
https://doaj.org/article/2f601ae8b55f479b8c22a48d1ff3137a
Autor:
Catherine Urban, Hannah V. Hayes, Giovanna Piraino, Vivian Wolfe, Patrick Lahni, Michael O’Connor, Ciara Phares, Basilia Zingarelli
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Endothelial dysfunction plays a central role in the pathogenesis of sepsis-mediated multiple organ failure. Several clinical and experimental studies have suggested that the glycocalyx is an early target of endothelial injury during an infection. Col
Externí odkaz:
https://doaj.org/article/8e53e81b93164256aacc6b412ef4d967
Autor:
David S. Vitale, Patrick Lahni, Lindsey Hornung, Tyler Thompson, Peter R. Farrell, Tom K. Lin, Jaimie D. Nathan, Hector R. Wong, Maisam Abu-El-Haija
Publikováno v:
PLoS ONE, Vol 17, Iss 2 (2022)
Background Acute pancreatitis (AP) is increasing in incidence in adult and pediatric patients. Identification of patients at high risk for progression to severe acute pancreatitis (SAP) is crucial, as it can lead to increased mortality and health sys
Externí odkaz:
https://doaj.org/article/e76acc3d71274bdfa24f5bda511a95e7
Autor:
Denise C. Hasson, Miki Watanabe-Chailland, Lindsey Romick-Rosendale, Adeleine Koterba, Dashiell S. Miner, Patrick Lahni, Qing Ma, Stuart L. Goldstein, Prasad Devarajan, Stephen W. Standage
Publikováno v:
American journal of physiology. Renal physiology. 323(3)
Acute kidney injury (AKI) is common in critically ill patients, and sepsis is its leading cause. Sepsis-associated AKI (SA-AKI) causes greater morbidity and mortality than other AKI etiologies, yet the underlying mechanisms are incompletely understoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b74718907024f40af3ec778e2d26c7
https://pubmed.ncbi.nlm.nih.gov/35834274
https://pubmed.ncbi.nlm.nih.gov/35834274
Autor:
Xenia Davis, Lauren Williamson, Joanna Stuck, Kendra Howell, Patrick Lahni, Giovanna Piraino, Vivian Wolfe, Rajib Mukherjee, Joan Sanchez-Gurmaches, Basilia Zingarelli, Jennifer Kaplan
Publikováno v:
Shock. 59:779-790
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15652d9571b81318e96455b176168a3b
https://doi.org/10.1097/shk.0000000000002105
https://doi.org/10.1097/shk.0000000000002105
Autor:
Satoshi Kikuchi, Giovanna Piraino, Michael O'Connor, Vivian Wolfe, Kiana Ridings, Patrick Lahni, Basilia Zingarelli
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Alterations in the energy homeostasis contribute to sepsis-mediated multiple organ failure. The liver plays a central role in metabolism and participates to the innate immune and inflammatory responses of sepsis. Several clinical and experimental stu
Externí odkaz:
https://doaj.org/article/ed70bf3e1d6f4f9996f0c9df4ecdbd10
Publikováno v:
Innate Immunity, Vol 25 (2019)
Neutrophils are the most abundant immune cell of the innate immune system and participate in essential immune functions. Heterogeneity within neutrophils has been documented, but it is difficult to distinguish if these are altered activation states o
Externí odkaz:
https://doaj.org/article/4a390860a5b242699e92f5d9ccf81b72
Autor:
Sidra Ishaque, Stephen Thomas Famularo, Ali Faisal Saleem, Naveed Ur Rehman Siddiqui, Zaubina Kazi, Sadia Parkar, Aneeta Hotwani, Neal J. Thomas, Jill Marie Thompson, Patrick Lahni, Brian Varisco, Nadir Yehya
Publikováno v:
Pediatric Critical Care Medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::decaeb68a841cc0bbde6cfdb525da6b5
https://doi.org/10.1097/pcc.0000000000003244
https://doi.org/10.1097/pcc.0000000000003244
Autor:
Monica L. Wagner, Allison Ammann, Giovanna Piraino, Vivian Wolfe, Michael O’Connor, Patrick Lahni, Assem Ziady, Basilia Zingarelli
Publikováno v:
Shock.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80bb88f8a8a0f62e1ae57b32438cd83e
https://doi.org/10.1097/shk.0000000000002134
https://doi.org/10.1097/shk.0000000000002134