Zobrazeno 1 - 10
of 225
pro vyhledávání: '"Patrick, Freund"'
Autor:
Tim M. Emmenegger, Raoul Seiler, Paul G. Unschuld, Patrick Freund, Jan Klohs, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Alzheimer’s disease (AD) is characterized by progressive episodic memory dysfunction. A prominent hallmark of AD is gradual brain atrophy. Despite extensive research on brain pathology, the understanding of spinal cord pathology in AD and
Externí odkaz:
https://doaj.org/article/b0e4a03e3de04c5282b86746aa12b0b1
Autor:
Nikolai Pfender, Catherine R. Jutzeler, Michèle Hubli, Paulina S. Scheuren, Dario Pfyffer, Carl M. Zipser, Jan Rosner, Susanne Friedl, Reto Sutter, José M. Spirig, Michael Betz, Martin Schubert, Maryam Seif, Patrick Freund, Mazda Farshad, Armin Curt, Markus Hupp
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionNew diagnostic techniques are a substantial research focus in degenerative cervical myelopathy (DCM). This cross-sectional study determined the significance of cardiac-related spinal cord motion and the extent of spinal stenosis as indica
Externí odkaz:
https://doaj.org/article/45ee06588a29403bb38e34700a4f1a34
Autor:
Anna Lebret, Simon Lévy, Nikolai Pfender, Mazda Farshad, Franziska C. S. Altorfer, Virginie Callot, Armin Curt, Patrick Freund, Maryam Seif
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The aim of this study was to determine tissue-specific blood perfusion impairment of the cervical cord above the compression site in patients with degenerative cervical myelopathy (DCM) using intravoxel incoherent motion (IVIM) imaging. A qu
Externí odkaz:
https://doaj.org/article/f0b2a424263f47789fe35f8e5bdce6b9
Publikováno v:
PLoS ONE, Vol 19, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/1765f5361e9a43bfbf6c9f03b086f2c0
Autor:
Nikolai Pfender, Jan Rosner, Carl M. Zipser, Susanne Friedl, Martin Schubert, Reto Sutter, Markus Klarhoefer, José M. Spirig, Michael Betz, Patrick Freund, Mazda Farshad, Armin Curt, Markus Hupp
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionDegenerative cervical myelopathy (DCM) is the most common cause of non-traumatic incomplete spinal cord injury, but its pathophysiology is poorly understood. As spinal cord compression observed in standard MRI often fails to explain a pat
Externí odkaz:
https://doaj.org/article/28355401b8eb42a290bd8a212a5606be
Publikováno v:
The Lancet. Neurology. 12(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd6b3062c78d2fc5142c0592a429924c
https://pubmed.ncbi.nlm.nih.gov/28845784
https://pubmed.ncbi.nlm.nih.gov/28845784
Autor:
Silvan Büeler, Marios C. Yiannakas, Zdravko Damjanovski, Patrick Freund, Martina D. Liechti, Gergely David
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Atrophy in the spinal cord (SC), gray (GM) and white matter (WM) is typically measured in-vivo by image segmentation on multi-echo gradient-echo magnetic resonance images. The aim of this study was to establish an acquisition and analysis pr
Externí odkaz:
https://doaj.org/article/b44bf60e5526462ab12f3f17c4bd8986
Autor:
Michela Azzarito, Tim M. Emmenegger, Gabriel Ziegler, Eveline Huber, Patrick Grabher, Martina F. Callaghan, Alan Thompson, Karl Friston, Nikolaus Weiskopf, Tim Killeen, Patrick Freund
Publikováno v:
NeuroImage, Vol 274, Iss , Pp 120128- (2023)
Motor skill learning relies on neural plasticity in the motor and limbic systems. However, the spatial and temporal characteristics of these changes—and their microstructural underpinnings—remain unclear. Eighteen healthy males received 1 h of tr
Externí odkaz:
https://doaj.org/article/c112b365ccd042e78ac59ee41ad0b966
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
ObjectivePreclinical studies have shown that cognitive impairments following spinal cord injury (SCI), such as impaired spatial memory, are linked to inflammation, neurodegeneration, and reduced neurogenesis in the right hippocampus. This cross-secti
Externí odkaz:
https://doaj.org/article/2cb846d1af8d49b99e5ccd96cf748296
Autor:
Simon Schading, Maryam Seif, Tobias Leutritz, Markus Hupp, Armin Curt, Nikolaus Weiskopf, Patrick Freund
Publikováno v:
NeuroImage, Vol 271, Iss , Pp 120046- (2023)
Short MRI acquisition time, high signal-to-noise ratio, and high reliability are crucial for image quality when scanning healthy volunteers and patients. Cross-sectional cervical cord area (CSA) has been suggested as a marker of neurodegeneration and
Externí odkaz:
https://doaj.org/article/cdf43f77a0b948dd8b9507ce60a27ab4