Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Patrick, Dumas"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Introduction: Hybrid modeling combining First-Principles with machine learning is becoming a pivotal methodology for Biopharma 4.0 enactment. Chinese Hamster Ovary (CHO) cells, being the workhorse for industrial glycoproteins production, have been th
Externí odkaz:
https://doaj.org/article/f2f3ed691a3c4435b69a016c5e18c1be
Autor:
Abdolrahim Yousefi-Darani, Olivier Paquet-Durand, Almut von Wrochem, Jens Classen, Jens Tränkle, Mario Mertens, Jeroen Snelders, Veronique Chotteau, Meeri Mäkinen, Alina Handl, Marvin Kadisch, Dietmar Lang, Patrick Dumas, Bernd Hitzmann
Publikováno v:
Sensors, Vol 22, Iss 15, p 5581 (2022)
Chemometric models for on-line process monitoring have become well established in pharmaceutical bioprocesses. The main drawback is the required calibration effort and the inflexibility regarding system or process changes. So, a recalibration is nece
Externí odkaz:
https://doaj.org/article/98206bd226af4b2aa150aae1bbf338f5
Genome-scale modeling of Chinese hamster ovary cells by hybrid semi-parametric flux balance analysis
Publikováno v:
Bioprocess and biosystems engineering. 45(11)
Flux balance analysis (FBA) is currently the standard method to compute metabolic fluxes in genome-scale networks. Several FBA extensions employing diverse objective functions and/or constraints have been published. Here we propose a hybrid semi-para
Publikováno v:
Microorganisms
Volume 7
Issue 12
Volume 7
Issue 12
Background: Flux analyses, such as Metabolic Flux Analysis (MFA), Flux Balance Analysis (FBA), Flux Variability Analysis (FVA) or similar methods, can provide insights into the cellular metabolism, especially in combination with experimental data. Th
Publikováno v:
Nanobiomedicine, Vol 5 (2018)
Nanobiomedicine
Nanobiomedicine
Tendon injuries can be difficult to heal and have high rates of relapse due to stress concentrations caused by scar formation and the sutures used in surgical repair. Regeneration of the tendon/ligament-to-bone interface is critical to provide functi
Publikováno v:
Vuibert, 2018
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International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::51179e14baca509e4a74e3a37b0862ea
https://hal.archives-ouvertes.fr/hal-01899164
https://hal.archives-ouvertes.fr/hal-01899164
Publikováno v:
Open Journal of Psychiatry. :110-114
Evidence suggests that the structure of psychosis-proneness in the general population may involve three distinct related dimensions. Therefore we conducted a study, using a wider range of measures, to explore the factorial structure of schizotypy ass
Publikováno v:
PSN. 1:20-26
Le trouble de personnalite schizotypique presente de tres nombreux points communs avec la schizophrenie, tant sur le plan clinique, ou il evoque une forme attenuee de la maladie, que sur les plans epidemiologique, neuropsychologique, electrophysiolog
Autor:
Thierry d'Amato, Nicolas Franck, Yann Coello, Jean Dalery, Yves Rossetti, Mohamed Saoud, Patrick Dumas
Publikováno v:
Cognitive Neuropsychiatry. 5:123-134
There is a challenge to understand schizophrenia cognitive deficits in terms of a common unifying hypothesis (i.e., context-processing deficit). We suggest that analysis of a low level of cognition, such as the natural tendency to adapt pointing move
Autor:
Thierry d'Amato, Christel Gutknecht, Jean Dalery, Sébastien Bouafia, Thierry Rochet, René Ecochard, Patrick Dumas, Mohamed Saoud
Publikováno v:
Psychiatry research. 109(1)
The literature suggests that cannabis use and schizotypal traits both constitute risk factors for the later development of schizophrenia. However, their interrelationships remain to be evaluated. The present study examined the association between can