Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Patricio Sáez-Briones"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3724 (2023)
It has recently been demonstrated that aromatic bromination at C(2) abolishes all typical psychomotor, and some key prosocial effects of the entactogen MDMA in rats. Nevertheless, the influence of aromatic bromination on MDMA-like effects on higher c
Externí odkaz:
https://doaj.org/article/38d4c01df5434290b911c14955a2fcf5
Autor:
Bernardita Cayupe, Blanca Troncoso, Carlos Morgan, Patricio Sáez-Briones, Ramón Sotomayor-Zárate, Luis Constandil, Alejandro Hernández, Eugenia Morselli, Rafael Barra
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11965 (2022)
A crucial etiological component in fetal programming is early nutrition. Indeed, early undernutrition may cause a chronic increase in blood pressure and cardiovascular diseases, including stroke and heart failure. In this regard, current evidence has
Externí odkaz:
https://doaj.org/article/0f596bca39fe499490dba79f532c6e1f
Autor:
Carlos Morgan, Patricio Sáez-Briones, Rafael Barra, Andrea Reyes, Katherine Zepeda-Morales, Luis Constandil, Miguel Ríos, Paulina Ramírez, Héctor Burgos, Alejandro Hernández
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 10089 (2022)
A loss of neuroplastic control on nucleus accumbens (NAc) neuronal activity exerted by the medial prefrontal cortex (mPFC) through long-term depression (LTD) is involved in triggering drug-seeking behavior and relapse on several substances of abuse d
Externí odkaz:
https://doaj.org/article/186a13e6d6504628a204cece526515b1
Autor:
David Bravo, Katherine Zepeda-Morales, Carola J. Maturana, Jeffri S. Retamal, Alejandro Hernández, Teresa Pelissier, Rafael Barra, Patricio Sáez-Briones, Héctor Burgos, Luis Constandil
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6705 (2022)
Pannexin 1 (Panx1) is involved in the spinal central sensitization process in rats with neuropathic pain, but its interaction with well-known, pain-related, ligand-dependent receptors, such as NMDA receptors (NMDAR) and P2X7 purinoceptors (P2X7R), re
Externí odkaz:
https://doaj.org/article/bbb8be88c0b74bb1b3018f325931cf79
Autor:
Jocelyn Solorza, Carolina A. Oliva, Karen Castillo, Gabriela Amestica, María Constanza Maldifassi, Xaviera A. López-Cortés, Rafael Barra, Jimmy Stehberg, Matthias Piesche, Patricio Sáez-Briones, Wendy González, Mauricio Arenas-Salinas, Trinidad A. Mariqueo
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Interleukin-1β (IL-1β) is an important cytokine that modulates peripheral and central pain sensitization at the spinal level. Among its effects, it increases spinal cord excitability by reducing inhibitory Glycinergic and GABAergic neurotransmissio
Externí odkaz:
https://doaj.org/article/a824e1b33c5545788d0ac776045cd6e5
Autor:
Bernardita Cayupe, Carlos Morgan, Gustavo Puentes, Luis Valladares, Héctor Burgos, Amparo Castillo, Alejandro Hernández, Luis Constandil, Miguel Ríos, Patricio Sáez-Briones, Rafael Barra
Publikováno v:
Molecules, Vol 26, Iss 12, p 3568 (2021)
Prenatally malnourished rats develop hypertension in adulthood, in part through increased α1-adrenoceptor-mediated outflow from the paraventricular nucleus (PVN) to the sympathetic system. We studied whether both α1-adrenoceptor-mediated noradrener
Externí odkaz:
https://doaj.org/article/0e12cd82d55f406fb517eabd8edc1e5e
Autor:
Patricio Sáez-Briones, Vicente Castro-Castillo, Gabriela Díaz-Véliz, Luis Valladares, Rafael Barra, Alejandro Hernández, Bruce K. Cassels
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
The entactogen MDMA (3,4-methylenedioxy-methamphetamine, “Ecstasy”) exerts its psychotropic effects acting primarily as a substrate of the serotonin transporter (SERT) to induce a non-exocytotic release of serotonin. Nevertheless, the roles of sp
Externí odkaz:
https://doaj.org/article/0d49ae635a7247d2a84373f0d5b0c631
Autor:
Jocelyn Solorza, Carolina A. Oliva, Karen Castillo, Gabriela Amestica, María Constanza Maldifassi, Xaviera A. López-Cortés, Rafael Barra, Jimmy Stehberg, Matthias Piesche, Patricio Sáez-Briones, Wendy González, Mauricio Arenas-Salinas, Trinidad A. Mariqueo
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology, Vol 12 (2021)
Indexación Scopus Interleukin-1β (IL-1β) is an important cytokine that modulates peripheral and central pain sensitization at the spinal level. Among its effects, it increases spinal cord excitability by reducing inhibitory Glycinergic and GABAerg
Autor:
Bruce K. Cassels, Gabriela Díaz-Véliz, Vicente Castro-Castillo, Alejandro Hernández, Luis Valladares, Patricio Sáez-Briones, Rafael Barra
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Frontiers in Pharmacology
Frontiers in Pharmacology
The entactogen MDMA (3,4-methylenedioxy-methamphetamine, “Ecstasy”) exerts its psychotropic effects acting primarily as a substrate of the serotonin transporter (SERT) to induce a non-exocytotic release of serotonin. Nevertheless, the roles of sp
Autor:
Rafael Barra, Luis Valladares, Christian Cofre, Patricio Sáez-Briones, Gustavo Puentes, Karina Hernández, Carlos Morgan, Alejandro Hernández, Luis Constandil, Miguel Rios, Héctor Burgos, Amparo Castillo, Luis A. Milla, Osvaldo Flores
Publikováno v:
Behavioural brain research. 363
Moderate reduction of dietary protein (from 25% to 8% casein) in pregnant rats, calorically compensated by carbohydrates, gives rise to ‘hidden prenatal malnutrition’ (HPM) in the offspring since it does not alter body and brain weights of pups a