Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Patricio Fernandez-Silva"'
Autor:
Yamilee Hurtado-Roca, Marta Ledesma, Monica Gonzalez-Lazaro, Raquel Moreno-Loshuertos, Patricio Fernandez-Silva, Jose Antonio Enriquez, Martin Laclaustra
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0163770 (2016)
Alterations of mitochondrial DNA copy number (mtDNAcn) in the blood (mitochondrial to nuclear DNA ratio) appear associated with several systemic diseases, including primary mitochondrial disorders, carcinogenesis, and hematologic diseases. Measuring
Externí odkaz:
https://doaj.org/article/d8fdc3ce704c49458779eb94415aa5ed
Autor:
Raquel Moreno-Loshuertos, Nieves Movilla, Joaquín Marco-Brualla, Ruth Soler-Agesta, Patricia Ferreira, José Antonio Enríquez, Patricio Fernández-Silva
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1300 (2023)
As the last step of the OXPHOS system, mitochondrial ATP synthase (or complex V) is responsible for ATP production by using the generated proton gradient, but also has an impact on other important functions linked to this system. Mutations either in
Externí odkaz:
https://doaj.org/article/d60bed66b48e4f928c36b7b54bd5c56e
Autor:
Laure Delavallée, Navrita Mathiah, Lauriane Cabon, Aurélien Mazeraud, Marie-Noelle Brunelle-Navas, Leticia K. Lerner, Mariana Tannoury, Alexandre Prola, Raquel Moreno-Loshuertos, Mathieu Baritaud, Laura Vela, Kevin Garbin, Delphine Garnier, Christophe Lemaire, Francina Langa-Vives, Martine Cohen-Salmon, Patricio Fernández-Silva, Fabrice Chrétien, Isabelle Migeotte, Santos A. Susin
Publikováno v:
Molecular Metabolism, Vol 40, Iss , Pp 101027- (2020)
Objectives: Apoptosis-Inducing Factor (AIF) is a protein involved in mitochondrial electron transport chain assembly/stability and programmed cell death. The relevant role of this protein is underlined because mutations altering mitochondrial AIF pro
Externí odkaz:
https://doaj.org/article/8c134e4208ad45a592079ac9a2feb0b1
Autor:
Adela Guarás, Ester Perales-Clemente, Enrique Calvo, Rebeca Acín-Pérez, Marta Loureiro-Lopez, Claire Pujol, Isabel Martínez-Carrascoso, Estefanía Nuñez, Fernando García-Marqués, María Angeles Rodríguez-Hernández, Ana Cortés, Francisca Diaz, Acisclo Pérez-Martos, Carlos T. Moraes, Patricio Fernández-Silva, Aleksandra Trifunovic, Plácido Navas, Jesús Vazquez, Jose A. Enríquez
Publikováno v:
Cell Reports, Vol 15, Iss 1, Pp 197-209 (2016)
Electrons feed into the mitochondrial electron transport chain (mETC) from NAD- or FAD-dependent enzymes. A shift from glucose to fatty acids increases electron flux through FAD, which can saturate the oxidation capacity of the dedicated coenzyme Q (
Externí odkaz:
https://doaj.org/article/398fede521514fbaa72a53db1ef4ebdc
Autor:
Rafael Piñol, Justyna Zeler, Carlos D. S. Brites, Yuanyu Gu, Pedro Téllez, Albano N. Carneiro Neto, Thiago E. da Silva, Raquel Moreno-Loshuertos, Patricio Fernandez-Silva, Ana Gallego, Luis Martinez-Lostao, Abelardo Martínez, Luís D. Carlos, Angel Millán
Measurement of thermogenesis in individual cells is a remarkable challenge due to the complexity of the biochemical environment (such as pH and ionic strength) and to the rapid and yet not well-understood heat transfer mechanisms throughout the cell.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0070705cc8d560893b7d63363579f85
Autor:
Raquel Moreno-Loshuertos, Gustavo Ferrín, Rebeca Acín-Pérez, M Esther Gallardo, Carlo Viscomi, Acisclo Pérez-Martos, Massimo Zeviani, Patricio Fernández-Silva, José Antonio Enríquez
Publikováno v:
PLoS Genetics, Vol 7, Iss 4, p e1001379 (2011)
About half of the mitochondrial DNA (mtDNA) mutations causing diseases in humans occur in tRNA genes. Particularly intriguing are those pathogenic tRNA mutations than can reach homoplasmy and yet show very different penetrance among patients. These m
Externí odkaz:
https://doaj.org/article/edf364bf23964d438441d5fb78b7a745