Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Patricio, Diosque"'
Autor:
Fanny Rusman, Anahí G Díaz, Tatiana Ponce, Noelia Floridia-Yapur, Christian Barnabé, Patricio Diosque, Nicolás Tomasini
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 11, p e0011764 (2023)
BackgroundTrypanosoma cruzi, the etiological agent of Chagas Disease, exhibits remarkable genetic diversity and is classified into different Discrete Typing Units (DTUs). Strain typing techniques are crucial for studying T. cruzi, because their DTUs
Externí odkaz:
https://doaj.org/article/7912b29c02144d2fbb2fd0261dd430d4
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Trypanosoma cruzi, as other kinetoplastids, has a complex mechanism of editing of mitochondrial mRNAs that requires guide RNAs (gRNAs) coded in DNA minicircles in the kinetoplast. There are many variations on this mechanism among species. mRNA editin
Externí odkaz:
https://doaj.org/article/98fa1318cd6c40728f00f6eba0fa2c69
Autor:
María E Bracamonte, Agustín Moya Álvarez, Andrea M Sosa, Carlos L Hoyos, Juan J Lauthier, Silvana P Cajal, Marisa Juarez, Renato E Uncos, Fernando J Sánchez-Valdéz, Leonardo Acuña, Patricio Diosque, Miguel A Basombrío, Julio R Nasser, Yoshihisa Hashiguchi, Masataka Korenaga, Paola A Barroso, Jorge D Marco
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232829 (2020)
The diagnosis of American tegumentary leishmaniasis (ATL) still requires the design of more effective tools. Leishmania (Viannia) braziliensis is the causal agent of the 90% of Argentinean ATL cases. Considering the current knowledge, an ELISA based
Externí odkaz:
https://doaj.org/article/f8d24d2a2bc94f8e8f3bfa09f22c5461
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 1, p e0007770 (2020)
BACKGROUND:Genetic exchange in Trypanosoma cruzi is controversial not only in relation to its frequency, but also to its mechanism. Parasexual genetic exchange has been proposed based on laboratory hybrids, but population genomics strongly suggests m
Externí odkaz:
https://doaj.org/article/2f81c86f608049cc87dab4a6c0fa7bf9
Autor:
Cecilia Pérez Brandán, Andrea C. Mesías, Cecilia Parodi, Rubén O. Cimino, Carolina Pérez Brandán, Patricio Diosque, Miguel Ángel Basombrío
Publikováno v:
BMC Infectious Diseases, Vol 17, Iss 1, Pp 1-9 (2017)
Abstract Background Previous studies showed that a naturally attenuated strain from Trypanosoma cruzi triggers an immune response mainly related to a Th2-type profile. Albeit this, a strong protection against virulent challenge was obtained after pri
Externí odkaz:
https://doaj.org/article/971d2864751548b1841c737e54994a83
Autor:
Fanny Rusman, Nicolás Tomasini, Noelia-Floridia Yapur, Andrea F Puebla, Paula G Ragone, Patricio Diosque
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 6, p e0007536 (2019)
BACKGROUND:Trypanosoma cruzi, the protozoan causative of Chagas disease, is classified into six main Discrete Typing Units (DTUs): TcI-TcVI. This parasite has around 105 copies of the minicircle hypervariable region (mHVR) in their kinetoplastic DNA
Externí odkaz:
https://doaj.org/article/d5a5ee9f006c4daa99efbc4dec448204
Autor:
Fanny Rusman, Noelia Floridia-Yapur, Anahí G Díaz, Tatiana Ponce, Patricio Diosque, Nicolás Tomasini
Publikováno v:
Molecular Biology and Evolution. 40
Kinetoplastids are a diverse group of flagellates which exhibit editing by insertion/deletion of Us in the mitochondrial mRNAs. Some mRNAs require editing to build most of their coding sequences, a process known as pan-editing. Evidence suggests that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3608eb983694800fa262a6503154d294
https://doi.org/10.1093/molbev/msad081
https://doi.org/10.1093/molbev/msad081
Autor:
Anahí G. Díaz, Paula G. Ragone, Fanny Rusman, Noelia Floridia-Yapur, Rubén M. Barquez, M. Mónica Díaz, Nicolás Tomasini, Patricio Diosque
Publikováno v:
Pathogens, Vol 9, Iss 9, p 731 (2020)
Trypanosomes are a group of parasitic flagellates with medical and veterinary importance. Despite many species having been described in this genus, little is known about many of them. Here, we report a genetic and morphological characterization of tr
Externí odkaz:
https://doaj.org/article/3ae905a179034dd98abf399de9e70962
Autor:
Nicolás Tomasini, Patricio Diosque
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 110, Iss 3, Pp 403-413 (2015)
Several different models of Trypanosoma cruzi evolution have been proposed. These models suggest that scarce events of genetic exchange occurred during the evolutionary history of this parasite. In addition, the debate has focused on the existence of
Externí odkaz:
https://doaj.org/article/34061008eb2545119a629cdda9715380
Autor:
Jailson FB Querido, María G Echeverría, Gerardo A Marti, Rita Medina Costa, María L Susevich, Jorge E Rabinovich, Aydee Copa, Nair A Montaño, Lineth Garcia, Marisol Cordova, Faustino Torrico, Rubén Sánchez-Eugenia, Lissete Sánchez-Magraner, Xabier Muñiz-Trabudua, Ibai López-Marijuan, Gabriela S Rozas-Dennis, Patricio Diosque, Ana M de Castro, Carlos Robello, Julio S Rodríguez, Jaime Altcheh, Paz M Salazar-Schettino, Marta I Bucio, Bertha Espinoza, Diego MA Guérin, Marcelo Sousa Silva
Publikováno v:
Parasites & Vectors, Vol 8, Iss 1, Pp 1-9 (2015)
Abstract Background Chagas disease is caused by Trypanosoma cruzi, and humans acquire the parasite by exposure to contaminated feces from hematophagous insect vectors known as triatomines. Triatoma virus (TrV) is the sole viral pathogen of triatomine
Externí odkaz:
https://doaj.org/article/d2308c1eaf9a470c857b19ff7b86d5fe