Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Patricija Zot"'
Autor:
Peyman Nejat, Areej Alsaafin, Ghazal Alabtah, Nneka I. Comfere, Aaron R. Mangold, Dennis H. Murphree, Patricija Zot, Saba Yasir, Joaquin J. Garcia, H. R. Tizhoosh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Patching whole slide images (WSIs) is an important task in computational pathology. While most of them are designed to classify or detect the presence of pathological lesions in a WSI, the confounding role and redundant nature of normal hist
Externí odkaz:
https://doaj.org/article/2c83a569c5024b958e63bae28d8efaf6
Autor:
Alicia E. Woock, Jacqueline M. Grible, Amy L. Olex, J. Chuck Harrell, Patricija Zot, Michael Idowu, Charles V. Clevenger
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract In breast cancer, prolactin-induced activation of the transcription factor STAT5a results from the phosphorylation of STAT5a tyrosine residue 694. However, its role in mammary oncogenesis remains an unsettled debate as STAT5a exhibits functi
Externí odkaz:
https://doaj.org/article/ac88965986da4b14922876d81cbc4694
Autor:
Jacqueline M. Grible, Patricija Zot, Amy L. Olex, Shannon E. Hedrick, J. Chuck Harrell, Alicia E. Woock, Michael O. Idowu, Charles V. Clevenger
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract The hormone prolactin (PRL) and its receptor (hPRLr) are significantly involved in breast cancer pathogenesis. The intermediate hPRLr (hPRLrI) is an alternatively-spliced isoform, capable of stimulating cellular viability and proliferation.
Externí odkaz:
https://doaj.org/article/4c18855c6cd74555a97c5428cf615799
Publikováno v:
ACG Case Reports Journal. 9:e00925
Purpose: Patients with Crohn’s disease (CD) are at higher risk of developing colorectal cancer (CRC) and gastrointestinal fistula. We report an unusual case of sigmoid colon adenocarcinoma in a CD patient that metastasized to the small bowel throug
Autor:
Michael O. Idowu, Charles V. Clevenger, Jacqueline M. Grible, Patricija Zot, Shannon E. Hedrick, Alicia E Woock, Amy L. Olex, J. Chuck Harrell
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-11 (2021)
NPJ Breast Cancer
NPJ Breast Cancer
The hormone prolactin (PRL) and its receptor (hPRLr) are significantly involved in breast cancer pathogenesis. The intermediate hPRLr (hPRLrI) is an alternatively-spliced isoform, capable of stimulating cellular viability and proliferation. An analog
Autor:
Raghavendra Pillappa, Michael O. Idowu, Kandace P. McGuire, Patricija Zot, Valentina Robila, Lorraine Colon Cartagena
Publikováno v:
Clinical breast cancer. 21(5)
Background Reducing the rate of margin positivity and reoperations remains a paramount goal in breast-conserving surgery (BCS). This study assesses the effectiveness of standard partial mastectomy with cavity shave margins (CSM) compared with partial
Autor:
Charles V. Clevenger, Patricija Zot, Jacqueline M. Grible, Alicia E Woock, J. Chuck Harrell, Idowu Michael
Publikováno v:
Journal of the Endocrine Society
The neuroendocrine hormone prolactin (PRL) and its cognate receptor (PRLr) have been implicated in the pathogenesis of breast cancer. PRL signaling relies on activating kinases such as the tyrosine kinase Jak2 and serine/threonine kinases ERK1/2, Nek
Autor:
Charles V. Clevenger, J. Chuck Harrell, Jacqueline M. Grible, Patricija Zot, Michael O. Idowu
Publikováno v:
Journal of the Endocrine Society
Epidemiological, cellular, and genetic analyses indicate the hormone prolactin (PRL) and its cognate receptor in humans (hPRLr) are significantly involved in breast cancer pathogenesis. Recent evidence demonstrated that a truncated mouse PRLr (mPRLrT
Publikováno v:
American Journal of Gastroenterology. 116:S1022-S1022
Autor:
Madhumitha Sriram, Michael O. Idowu, Patricija Zot, J. Chuck Harrell, Mohammad A. Alzubi, Tia H. Turner, Sahib S. Sohal
Publikováno v:
Clinicalexperimental metastasis. 36(3)
Advanced breast cancer often spreads to the bone, brain, liver, and lungs. The survival time of a patient with breast cancer liver metastasis is often less than 9 months without treatment. Experimental model systems often focus on the lung as a site