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pro vyhledávání: '"Patricia Y. Kelley"'
Publikováno v:
Journal of Neurosurgery. 82:847-857
✓ Our earlier investigations of the biology of the epidermal growth factor receptor (EGFR) in human gliomas demonstrated that the level of EGFR expression did not directly predict the glioma growth response to EGF, suggesting that the function of t
Publikováno v:
Journal of neurosurgery. 82(5)
✓ The epidermal growth factor receptor (EGFR) gene is amplified in over 40% of primary human glioblastomas and overexpressed in the majority. The authors' investigations demonstrate that the function of the EGFR in glioblastomas is distinct from th
Publikováno v:
Journal of Neurosurgery. 71:83-90
✓ Human glioblastomas are highly malignant intracranial tumors, some of which demonstrate amplification of the epidermal growth factor-receptor (EGF-R) gene. Overexpression of this gene is seen in the majority of primary tumors; however, the role o