Výsledky vyhledávání - "Patricia Xavier Santi"

Cardiac Safety of the Trastuzumab Biosimilar ABP 980 in Women with HER2-Positive Early Breast Cancer in the Randomized, Double-Blind, Active-Controlled LILAC Study

Autor: Marco Colleoni, Yasuhiro Fujiwara, Vladimir Hanes, Hans Christian Kolberg, Patricia Xavier Santi, Hans Tesch, Zorica Tomasevic, Georgia Demetriou

Publikováno v: Drug Safety

Although the human epidermal growth factor receptor 2 (HER2) blocker trastuzumab is generally well tolerated, cardiotoxicity can be an important therapeutic limitation.Objective.In this prespecified analysis, we compared the cardiac safety of the tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da2bedc0bcd0744591a89030a5a458e
http://europepmc.org/articles/PMC7048858

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Abstract OT1-03-04: The importance of central pathology pCR review in an international multicenter neoadjuvant study in HER2 positive early breast cancer - Results of the ABP 980 LILAC trial

Autor: Vladimir Hanes, Hans Tesch, Hanz-Christian Kolberg, Marco Colleoni, Yasuhiro Fujiwara, Patricia Xavier Santi, Georgia Demetriou

Publikováno v: Cancer Research. 80:OT1-03

Pathological complete response (pCR) after neoadjuvant therapy is an accepted surrogate endpoint for breast cancer registration trials and is a strong prognostic biomarker especially in high-risk tumor biology. The LILAC study, a comparative trial fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d9ce5ffe285a89f3d8db2279d987b424
https://doi.org/10.1158/1538-7445.sabcs19-ot1-03-04

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Use of Guarana for Hot Flashes after Breast Cancer: Randomized, Double-Blind, Placebo-Controlled Phase II Trial

Autor: Abna Faustina de Sousa Vieira, Patricia Xavier Santi, Vitor Augusto Queiroz Mauad, Auro Del Giglio, Daniel de Iracema Gomes Cubero

Publikováno v: Journal of Natural Remedies, Vol 19, Iss 1, Pp 1-11 (2019)

Background: Hot flashes are common in menopausal women and significantly affect the quality of life of many patients diagnosed with breast cancer for which hormone replacement therapy is not indicated. In a previous uncontrolled study, guarana (Paull

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81955f3c91690f2281dab06ee9f4a53e
https://doi.org/10.18311/jnr/2019/22737

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Cardiac safety of the trastuzumab biosimilar ABP 980 in women with HER2-positive early breast cancer in the LILAC study

Autor: Marco Colleoni, Patricia Xavier Santi, Yasuhiro Fujiwara, Vladimir Hanes, Zorica Tomasevic, Hans Tesch, Georgia Demetriou, Hans-Christian Kolberg

Publikováno v: Journal of Clinical Oncology. 37:557-557

557 Background: Although trastuzumab is generally well-tolerated, cardiotoxicity is the main limitation in its use, leading to a severe heart failure in 2-4% of patients in adjuvant trials. In the phase 3 LILAC trial, trastuzumab biosimilar ABP 980 d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a0749251dbec05fd54fd9eb3ead0088
https://doi.org/10.1200/jco.2019.37.15_suppl.557

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Paullinia cupana for control of hot flashes in breast cancer patients: a pilot study

Autor: Livia Tiemi, Rebecca Melo Zanellato, Saulo Silva Oliveira, Auro Del Giglio, Lucas Reifur, Patricia Xavier Santi, Tatiana Goberstein Lerner, Adriana Braz del Giglio

Publikováno v: Einstein (São Paulo), Vol 11, Iss 4, Pp 435-438
Einstein (São Paulo), Volume: 11, Issue: 4, Pages: 435-438, Published: DEC 2013
einstein (São Paulo) v.11 n.4 2013
Einstein (São Paulo)
Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
instacron:IIEPAE

OBJETIVO: Avaliar se a Paullinia cupana diminui o número e a gravidade dos fogachos em mulheres após diagnóstico de câncer de mama. MÉTODOS: Estudo piloto prospectivo fase II realizado com mulheres que sobreviveram ao câncer de mama, que comple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94fcebe37ba2319f133255a574634f67
https://doi.org/10.1590/s1679-45082013000400005

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Efficacy analyses of central laboratory pCR results from the LILAC study comparing the biosimilar ABP 980 and trastuzumab

Autor: Vladimir Hanes, Yasuhiro Fujiwara, N Zhang, Zorica Tomasevic, Patricia Xavier Santi, Georgia Demetriou, Hans Tesch, Hans-Christian Kolberg, Marco Colleoni

Publikováno v: Journal of Clinical Oncology. 36:583-583

583Background: The phase 3 LILAC Study compared ABP 980 with trastuzumab (TRAS) on pathologic complete response (pCR) in women with HER2+ early breast cancer. The primary efficacy results, based on...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9b33111fb3c3773511af45cb95070156
https://doi.org/10.1200/jco.2018.36.15_suppl.583

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Adjuvant treatment delay in breast cancer patients

Autor: Patricia Xavier Santi, Leandro Luongo de Matos, Auro Del Giglio, Damila Cristina Trufelli

Publikováno v: Revista da Associação Médica Brasileira v.61 n.5 2015
Revista da Associação Médica Brasileira
Associação Médica Brasileira (AMB)
instacron:AMB
Revista da Associação Médica Brasileira, Volume: 61, Issue: 5, Pages: 411-416, Published: OCT 2015
Revista da Associação Médica Brasileira, Vol 61, Iss 5, Pp 411-416 (2015)

Summary Background: to evaluate if time between surgery and the first adjuvant treatment (chemotherapy, radiotherapy or hormone therapy) in patients with breast cancer is a risk factor for lower overall survival (OS). Method: data from a five-year re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2576cd15ce94254e71dfa1b685366dc1
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302015000500411

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Applicability of modified Glasgow Prognostic Score in the assessment of elderly patients with cancer: A pilot study

Autor: Viviane Lealdini, Damila Cristina Trufelli, Leandro Luongo de Matos, Savia Raquel Costa Normando, Fernando Luiz Affonso Fonseca, Auro Del Giglio, Patricia Xavier Santi, Elisa Watanabe Camargo, Fernanda Borges Ferreira da Silva

Publikováno v: Journal of geriatric oncology. 6(6)

Objectives To evaluate the relationship between inflammatory parameters through the modified Glasgow Prognostic Score (mGPS) and other clinical characteristics of elderly patients with cancer, including frailty evaluated by the Edmonton Frailty Scale

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089423af9face2144402e13c30d4ea60
https://pubmed.ncbi.nlm.nih.gov/26439755

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Uncaria tomentosa (cat's claw) improves quality of life in patients with advanced solid tumors

Autor: Damila Cristina Trufelli, Suelen Patrícia dos Santos Martins, Daniel de Iracema Gomes Cubero, Auro Del Giglio, Felipe Melo Cruz, Patricia Xavier Santi, Fernando Luiz Affonso Fonseca, Eliana Araújo da Silva, Larissa Carvalho Lopes de Paula, Fábio Ferreira Perazzo

Publikováno v: Journal of alternative and complementary medicine (New York, N.Y.). 21(1)

Cat's claw (Uncaria tomentosa) is a native Amazon plant that exhibits anti-inflammatory and antitumor properties. We wanted to assess its activity for symptom management of terminal cancer patients.This prospective phase II study assessed the effects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b235fa7898d8c87095ec97b85cd789
https://pubmed.ncbi.nlm.nih.gov/25495394

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