Výsledky vyhledávání - "Patricia W. Bollman"

Whole Exome Sequencing of Philadelphia-Negative (Ph-negative) Myeloproliferative Neoplasms (MPNs) and Myelodysplastic/Myeloproliferative Disorders (MDS/MPD)

Autor: Tarcila Santos Datoguia, Alanna Mara P. S. Bezerra, Adriana Valente Fadel, Leandro de Padua, Guilherme Fleury Perini, Rodrigo Santucci, Sandra Saemi Nakashima, Paulo Augusto Achucarro Silveira, Leila Martins Perobelli, Rodolfo Daniel de Almeida Soares, Marco Aurelio Salvino, Erika M. M. Costa, Elvira Deolinda Rodrigues Pereira Velloso, Marinus M. Lima, Bianca Lisboa, Denise da Cunha Pasqualin, Paulo Vidal Campregher, Ricardo Helman, Welbert Oliveira Pereira, Eizabeth Xisto Souto, Michelli da Silva Diniz, Fabio P. Santos, Danielle Leão Cordeiro de Farias, Patricia W. Bollman, Isabel Bello, Mariana Miyagi, João Carlos de Campos Guerra, Evelyn H. A. da Mata, Vinicius R. P. Mattos, Juliane Musacchio, Nelson Hamerschlak, Marcia Higashi, Renato David Puga, Nydia Strachman Bacal, Carolina Kassab, Ana Fernandes Schriefer

Publikováno v: Blood. 124:4593-4593

Introduction: The development of next-generation sequencing has made it feasible to interrogate the entire genome or exome (coding genome) in a single experiment. Accordingly, our knowledge of the somatic mutations that cause cancer has increased exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b85edab304dafbdcc1df086ea1fe2614
https://doi.org/10.1182/blood.v124.21.4593.4593

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The Presence of ASXL1 Mutations As Well As a Total Number of Myeloid Driver Mutations Higher Than Two Is Strongly Associated with the Diagnosis of Primary Myelofibrosis As Opposed to Essential Thrombocythemia

Autor: Ana Fernandes Schriefer, Evelyn Helena Ascendino, Rodolfo Daniel de Almeida Soares, Guilherme Fleury Perini, Leila Martins Perobelli, Rodrigo Santucci, Manuela Pinto Tibúrcio, Marcia Higashi, Renato David Puga, João Carlos de Campos Guerra, Denise da Cunha Pasqualin, Nydia Strachman Bacal, Elvira Deolinda Rodrigues Pereira Velloso, Patricia W. Bollman, Marinus M. Lima, Sandra Nakashima Yoshida, Carolina Kassab, Isabel Bello, Roberta Cardoso Petroni, Alanna Mara P. S. Bezerra, Welbert Oliveira Pereira, Paulo Augusto Achucarro Silveira, Fernando Ferreira Costa, Marco Aurelio Salvino, Danielle Leão Cordeiro de Farias, Adriana Valente Fadel, Erika M. M. Costa, Bianca Lisboa, Leandro de Padua, Tarcila Santos Datoguia, Nelson Hamerschlak, Juliane Musacchio, Paulo Vidal Campregher, Eizabeth Xisto Souto, Michelli da Silva Diniz, Fabio P. Santos, Mariana Miyagi, Vinicius R. P. Mattos, Ricardo Helman

Publikováno v: Blood. 124:4595-4595

Introduction: Primary Myelofibrosis (PMF) and Essential Thrombocythemia (ET) are myeloproliferative neoplasms with similar genetic backgrounds. Both diseases are characterized, at the molecular level, by mutations in the genes JAK2, MPL and CALR. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ceda4284694b347c76d4377292bb7f5e
https://doi.org/10.1182/blood.v124.21.4595.4595

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Incidence and Impact of Activating Mutations of the RAS-RAF-MEK-ERK Pathway in Patients with Philadelphia-Negative (Ph-negative) Myeloproliferative Neoplasms (MPNs) and Myelodysplastic/Myeloproliferative Disorders–Unclassified (MDS/MPD-U)

Autor: Patricia W. Bollman, Fabio P. Santos, Isabel Bello, Evelyn H. A. da Mata, Ricardo Helman, Marco Aurelio Salvino, Welbert Oliveira Pereira, Alanna Mara P. S. Bezerra, Ana Fernandes Schriefer, Mariana Miyagi, Vinicius R. P. Mattos, Adriana Valente Fadel, Rodolfo Daniel de Almeida Soares, Juliane Musacchio, João Carlos de Campos Guerra, Nydia Strachman Bacal, Sandra Saemi Nakashima, Danielle Leão Cordeiro de Farias, Carolina Kassab, Guilherme Fleury Perini, Marcia Higashi, Paulo Vidal Campregher, Erika M. M. Costa, Bianca Lisboa, Renato David Puga, Tarcila Santos Datoguia, Eizabeth Xisto Souto, Michelli da Silva Diniz, Leila Martins Perobelli, Marinus M. Lima, Nelson Hamerschlak, Denise da Cunha Pasqualin, Rodrigo Santucci, Elvira Deolinda Rodrigues Pereira Velloso, Leandro de Padua, Paulo Augusto Achucarro Silveira

Publikováno v: Blood. 124:3172-3172

Introduction: Mutations that activate the RAS-RAF-MEK-ERK pathway have long been known to occur in patients with solid tumors and hematological malignancies. The most common mutations occur in the Ras family of GTPases (HRAS, NRAS, KRAS) and the Raf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94cd84af29d5c7b6378554af864864cf
https://doi.org/10.1182/blood.v124.21.3172.3172

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Genomic Profile of Patients with Triple Negative (JAK2, CALR and MPL) Essential Thrombocythemia and Primary Myelofibrosis

Publikováno v: Blood. 124:4589-4589

Introduction: Essential Thrombocythemia (ET) and Primary Myelofibrosis (PMF) are myeloproliferative neoplasms (MPN) with similar driver mutations. The three hallmark molecular alterations in these diseases are JAK2, MPL and CALR mutations. Patients w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::437dcdd35be414c11c1be8fdf49bda91
https://doi.org/10.1182/blood.v124.21.4589.4589

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