Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Patricia V, Lawford"'
Autor:
Daniel J. Taylor, Louise Aubiniere-Robb, Rebecca Gosling, Tom Newman, D. Rodney Hose, Ian Halliday, Patricia V. Lawford, Andrew J. Narracott, Julian P. Gunn, Paul D. Morris
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundIncreased coronary microvascular resistance (CMVR) is associated with coronary microvascular dysfunction (CMD). Although CMD is more common in women, sex-specific differences in CMVR have not been demonstrated previously.AimTo compare CMVR
Externí odkaz:
https://doaj.org/article/c271b04563154ee089f6c6a8942328ac
Autor:
Gareth J Williams, BMBS, Abdulaziz Al-Baraikan, MSc, Frank E Rademakers, ProfMD, Fabio Ciravegna, ProfPhD, Frans N van de Vosse, ProfPhD, Allan Lawrie, ProfPhD, Alexander Rothman, PhD, Euan A Ashley, ProfDphil, Martin R Wilkins, ProfMD, Patricia V Lawford, ProfPhD, Stig W Omholt, ProfPhD, Ulrik Wisløff, ProfPhD, D Rodney Hose, ProfPhD, Timothy J A Chico, ProfMD, Julian P Gunn, ProfMD, Paul D Morris, PhD
Publikováno v:
The Lancet: Digital Health, Vol 5, Iss 7, Pp e467-e476 (2023)
Summary: The past decade has seen a dramatic rise in consumer technologies able to monitor a variety of cardiovascular parameters. Such devices initially recorded markers of exercise, but now include physiological and health-care focused measurements
Externí odkaz:
https://doaj.org/article/2dae23871e944ee9a8e3aa1c127e5a9a
Autor:
Roshni Solanki, Rebecca Gosling, Vignesh Rammohan, Giulia Pederzani, Pankaj Garg, James Heppenstall, D. Rodney Hose, Patricia V. Lawford, Andrew J. Narracott, John Fenner, Julian P. Gunn, Paul D. Morris
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Three dimensional (3D) coronary anatomy, reconstructed from coronary angiography (CA), is now being used as the basis to compute ‘virtual’ fractional flow reserve (vFFR), and thereby guide treatment decisions in patients with coronary ar
Externí odkaz:
https://doaj.org/article/f68f07091b844a7cad1110d6d918e83f
Autor:
Hazel Arfah Haley, Mina Ghobrial, Paul D. Morris, Rebecca Gosling, Gareth Williams, Mark T. Mills, Tom Newman, Vignesh Rammohan, Giulia Pederzani, Patricia V. Lawford, Rodney Hose, Julian P. Gunn
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
The current management of acute coronary syndromes (ACS) is with an invasive strategy to guide treatment. However, identifying the lesions which are physiologically significant can be challenging. Non-invasive imaging is generally not appropriate or
Externí odkaz:
https://doaj.org/article/db5905a438ac44c1be70ad4d0f716310
Autor:
Paul D. Morris, PhD, Daniel Alejandro Silva Soto, PhD, Jeroen F.A. Feher, MSc, Dan Rafiroiu, PhD, Angela Lungu, PhD, Susheel Varma, PhD, Patricia V. Lawford, PhD, D. Rodney Hose, PhD, Julian P. Gunn, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 2, Iss 4, Pp 434-446 (2017)
Fractional flow reserve (FFR)-guided percutaneous intervention is superior to standard assessment but remains underused. The authors have developed a novel “pseudotransient” analysis protocol for computing virtual fractional flow reserve (vFFR) b
Externí odkaz:
https://doaj.org/article/c73dd0d852ee45d7abb395d5830bc85b
Autor:
Rebecca C Gosling, Eleanor Gunn, Hua Liang Wei, Yuanlin Gu, Vignesh Rammohan, Timothy Hughes, David Rodney Hose, Patricia V Lawford, Julian P Gunn, Paul D Morris
Publikováno v:
European Heart Journal - Digital Health. 3:481-488
Aims Angiography-derived fractional flow reserve (angio-FFR) permits physiological lesion assessment without the need for an invasive pressure wire or induction of hyperaemia. However, accuracy is limited by assumptions made when defining the distal
Autor:
Louise Aubiniere-Robb, Rebecca Gosling, Daniel J. Taylor, Tom Newman, D. Rodney Hose, Ian Halliday, Patricia V. Lawford, Andrew J. Narracott, Julian P. Gunn, Paul D. Morris
Publikováno v:
Nature Cardiovascular Research. 1:611-616
Fractional flow reserve (FFR) is the current gold standard invasive assessment of coronary artery disease (CAD). FFR reports coronary blood flow (CBF) as a fraction of a hypothetical and unknown normal value. Although used routinely to diagnose CAD a
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Computational modeling has been used routinely in the pre-clinical development of medical devices such as coronary artery stents. The ability to simulate and predict physiological and structural parameters such as flow disturbance, wall shear-stress,
Externí odkaz:
https://doaj.org/article/983f9e615fa842c79e0536b1d4a4f0bf
Autor:
D. Rodney Hose, Roberto T F Newcombe, Rebecca Gosling, Patricia V. Lawford, Julian Gunn, Vignesh Rammohan, Paul Morris
Publikováno v:
European Heart Journal - Digital Health. 2:616-625
Aims International guidelines mandate the use of fractional flow reserve (FFR) and/or non-hyperaemic pressure ratios to assess the physiological significance of moderate coronary artery lesions to guide revascularization decisions. However, they rema
Autor:
D. Rodney Hose, Patricia V. Lawford, Heynric B. Grotenhuis, Israel Valverde, Philipp Beerbaum, Yubing Shi
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
J Biol Phys
instname
J Biol Phys
Non-invasive estimation of the pressure gradient in cardiovascular stenosis has much clinical importance in assisting the diagnosis and treatment of stenotic diseases. In this research, a systematic comparison is conducted to investigate the accuracy