Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Patricia Ubieto-Capella"'
Autor:
Patricia Ubieto-Capella, Pilar Ximénez-Embún, Daniel Giménez-Llorente, Ana Losada, Javier Muñoz, Juan Méndez
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114024- (2024)
Summary: Mouse embryonic stem cells (mESCs) in the primed pluripotency state, which resembles the post-implantation epiblast, can be de-differentiated in culture to a naive state that resembles the pre-implantation inner cell mass. We report that pri
Externí odkaz:
https://doaj.org/article/de8baade3db844c4bea1848d82e199f9
Autor:
Teresa Fuertes, Emigdio Álvarez-Corrales, Carmen Gómez-Escolar, Patricia Ubieto-Capella, Álvaro Serrano-Navarro, Antonio de Molina, Juan Méndez, Almudena R. Ramiro, Virginia G. de Yébenes
Publikováno v:
Cell Death and Disease, Vol 14, Iss 10, Pp 1-13 (2023)
Abstract Diffuse large B cell lymphoma (DLBCL) is the most common aggressive B cell lymphoma and accounts for nearly 40% of cases of B cell non-Hodgkin lymphoma. DLBCL is generally treated with R-CHOP chemotherapy, but many patients do not respond or
Externí odkaz:
https://doaj.org/article/9379e2de340e481cb06088a6a79cb0c0
Autor:
Sergio Muñoz, Sonia Barroso, Nibal Badra-Fajardo, José Javier Marqueta-Gracia, María L. García-Rubio, Patricia Ubieto-Capella, Juan Méndez, Andrés Aguilera
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113778- (2024)
Summary: During genome duplication, replication forks (RFs) can be stalled by different obstacles or by depletion of replication factors or nucleotides. A limited number of histone post-translational modifications at stalled RFs are involved in RF pr
Externí odkaz:
https://doaj.org/article/5cd5f967db0f4b3486274166c63a0bf2
Autor:
Teresa Fuertes, Emigdio Álvarez-Corrales, Patricia Ubieto-Capella, Álvaro Serrano-Navarro, Carmen Gómez-Escolar, Antonio de Molina, Juan Méndez, Almudena R. Ramiro, Virginia G. de Yébenes
Diffuse large B cell lymphoma (DLBCL) is the most common aggressive B cell lymphoma and accounts for nearly 40% of cases of B cell non-Hodgkin lymphoma. DLBCL is generally treated with R-CHOP chemotherapy, but many patients do not respond or relapse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2315f3cb4bae1d04bd8a3c8ed83731a2
https://doi.org/10.1101/2022.09.27.509662
https://doi.org/10.1101/2022.09.27.509662
Autor:
Susana Llanos, Karun Mutreja, Patricia Ubieto-Capella, Samuel Miguez, Daniel González-Acosta, Juan Méndez, Fernando García, Elena Blanco-Romero, Javier Munoz, Luis Blanco, Massimo Lopes
Publikováno v:
The EMBO Journal
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
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DNA interstrand crosslinks (ICLs) induced by endogenous aldehydes or chemotherapeutic agents interfere with essential processes such as replication and transcription. ICL recognition and repair by the Fanconi Anemia pathway require the formation of a
Autor:
Javier Munoz, Antonio Galarreta, Patricia Ubieto-Capella, Marcos Malumbres, Eduardo Zarzuela, Emilio Lecona, Oscar Fernandez-Capetillo, Pablo Valledor, Vanesa Lafarga
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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EMBO J
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EMBO J
Chemical inhibitors of the deubiquitinase USP7 are currently being developed as anticancer agents based on their capacity to stabilize P53. Regardless of this activity, USP7 inhibitors also generate DNA damage in a p53-independent manner. However, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c74aac266686e70574d8af2edd6d1fb1
http://hdl.handle.net/10261/271123
http://hdl.handle.net/10261/271123
Autor:
Emilio Lecona, Patricia Ubieto-Capella, André Franz, Domenic Pilger, Thorsten Hoppe, Antonio Galarreta, Fabian den Brave, Pablo Valledor, Guillermo de la Vega-Barranco, Alejandro Fernández-Llorente, Vanesa Lafarga, Oscar Fernandez-Capetillo
Publikováno v:
Cell Reports
Summary The AAA+ ATPase VCP regulates the extraction of SUMO and ubiquitin-modified DNA replication factors from chromatin. We have previously described that active DNA synthesis is associated with a SUMO-high/ubiquitin-low environment governed by th