Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Patricia Shepherd"'
Autor:
Anna Hundt Golden, Meghan Hufstader Gabriel, Jon Russo, Mark Price, Stephen Ruhmel, Ami Nilsson, Patricia Shepherd Delong, Jennifer Jelsma, Michelle Carty
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 7, Iss 1, Pp 1-10 (2023)
Abstract Background Patient-reported outcome (PRO) measures provide valuable evidence in clinical trials; however, poor compliance with PRO measures is a notable and long-standing problem, resulting in missing data that potentially impact the interpr
Externí odkaz:
https://doaj.org/article/1e899e8296604af4a7e147fe7f90b0bd
Autor:
Golden, Anna Hundt, Gabriel, Meghan Hufstader, Russo, Jon, Price, Mark, Ruhmel, Stephen, Nilsson, Ami, Delong, Patricia Shepherd, Jelsma, Jennifer, Carty, Michelle
Publikováno v:
Journal of Patient-Reported Outcomes; 12/12/2023, Vol. 7 Issue 1, p1-10, 10p
Portal hypertension with varices developed in 18/675 patients with chronic myeloid leukaemia (CML) in a randomized trial comparing busulphan with busulphan and thioguanine. All 18 had received the drug combination and none busulphan alone (P less tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75561575851aebf6ff8a0229fed0d9a5
https://ora.ox.ac.uk/objects/uuid:cfab1dab-d98b-4274-b548-a184ee117110
https://ora.ox.ac.uk/objects/uuid:cfab1dab-d98b-4274-b548-a184ee117110
Autor:
Klaas J. Roozendaal, J.H. Frederik Falkenburg, Claire Chapman, Sue Richards, Saskia le Cessie, H. Berna Beverloo, Georgina Buck, Anthony R. Green, Hans van der Lelie, Alison E. Milne, David Bareford, Patricia Shepherd, Petra Muus, Tim Littlewood, Hanneke C. Kluin-Nelemans
Publikováno v:
Blood, 103, 4408-15
Blood, 103, 12, pp. 4408-15
Blood, 103(12), 4408-4415. American Society of Hematology
Blood, 103, 12, pp. 4408-15
Blood, 103(12), 4408-4415. American Society of Hematology
Item does not contain fulltext The optimal dose of interferon-alfa (IFN) for chronic myeloid leukemia (CML) is unknown. Retrospective analyses suggest that low doses are as effective as high doses, with less toxicity and fewer patients abandoning the
Autor:
Dietger Niederwieser, Thomas Friedrich, Michael W. Deininger, Christina Franke, Evelin Hennig, Thomas Bumm, Erika Schmidt, Knut Krohn, Patricia Shepherd, Christel Müller, R. Krahl, Sabine Leiblein, Haifa Kathrin Al-Ali
Publikováno v:
Blood. 101:1941-1949
Chronic myelogenous leukemia (CML) is characterized by the presence of a Bcr-Abl fusion protein with deregulated tyrosine kinase activity that is required for maintaining the malignant phenotype. Imatinib, a selective inhibitor ofBcr-Abl, induces maj
Autor:
Peter R. E. Johnson, Margaret Cook, Anil Lakhani, Patrick Carrington, Daniel Catovsky, Richard Kaczmarski, Ranjit V Thomas, Isabel Ribeiro, Patricia Shepherd
Publikováno v:
British Journal of Haematology. 116:341-345
Chronic lymphocytic leukaemia (CLL) is a B-cell disorder, which has a median survival of over 10 years from diagnosis for stage A disease. The natural history of stage A disease is generally indolent or only slowly progressive. It is less well known
Autor:
Colin Grace, Anthony J. Bench, Alistair Reid, Brian J. P. Huntly, Elizabeth P. Nacheva, Nick Telford, Patricia Shepherd, Jeff Szer, Lynda J. Campbell, Henry Miles Prince, Anthony R. Green, P Turner
Publikováno v:
Blood. 98:1732-1738
Chronic myeloid leukemia (CML) is characterized by formation of the BCR-ABL fusion gene, usually as a consequence of the Philadelphia (Ph) translocation between chromosomes 9 and 22. Large deletions on the derivative chromosome 9 have recently been r
Autor:
James S. Wainscoat, Paul McGale, Patricia Shepherd, J Boultwood, Susan Richards, Andrew Peniket, Fiona Watkins, Carrie Fidler, Timothy Littlewood
Publikováno v:
Blood. 96:358-361
Telomere shortening is associated with disease evolution in chronic myelogenous leukemia (CML). We have examined the relationship between diagnostic telomere length and outcome in 59 patients with CML who entered into the MRC CMLIII Trial by Southern
Autor:
James S. Wainscoat, A. Gaiger, Carrie Fidler, Andrew Peniket, Joanna Snowball, J Boultwood, Sara Haynes, Timothy Littlewood, Fiona Watkins, Patricia Shepherd, Rajko Kusec
Publikováno v:
American Journal of Hematology. 61:5-9
We studied telomere length in the peripheral blood leukocyte samples of a large group of patients with chronic myelogenous leukemia (CML) by Southern blot hybridization using the (TTAGGG)4 probe. The average telomere length expressed as the peak telo
Publikováno v:
The Lancet. 345:1392-1397
Interferon-alpha may be better than cytotoxic drugs in the long-term management of patients with chronic myeloid leukaemia (CML) in chronic phase. To test this possibility 587 patients with CML in chronic phase were randomly allocated to receive lymp