Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Patricia Salvati"'
Autor:
Susana Benítez-Robaina, Ángel Ramos-Macias, Silvia Borkoski-Barreiro, Juan Carlos Falcón-González, Patricia Salvatierra, Ángel Ramos-de Miguel
Publikováno v:
Journal of International Advanced Otology, Vol 18, Iss 6, Pp 465-470 (2022)
Externí odkaz:
https://doaj.org/article/46f2fe2fe51b4e0f9703d88e23a67f02
Autor:
Leonardo Pisani, Orazio Nicolotti, Céline Le Bourdonnec Passeleu, Angelo Carotti, Carla Caccia, Patricia Salvati, Francesco Leonetti, Giovanni Muncipinto, Teresa Fabiola Miscioscia, Ramón Soto-Otero, Estefanía Méndez-Álvarez, Marco Catto
Publikováno v:
Journal of Medicinal Chemistry. 52:6685-6706
In an effort to discover novel selective monoamine oxidase (MAO) B inhibitors with favorable physicochemical and pharmacokinetic profiles, 7-[(m-halogeno)benzyloxy]coumarins bearing properly selected polar substituents at position 4 were designed, sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31897fe2b14964b449a99ffa50f4c52a
https://doi.org/10.1021/jm9010127
https://doi.org/10.1021/jm9010127
Autor:
Leonardo Pisani, Jin Wang, Patricia Salvati, Angelo Carotti, Dale E. Edmondson, Claudia Binda, C. Caccia, Andrea Mattevi
Publikováno v:
Journal of Medicinal Chemistry. 50:5848-5852
Structures of human monoamine oxidase B (MAO B) in complex with safinamide and two coumarin derivatives, all sharing a common benzyloxy substituent, were determined by X-ray crystallography. These compounds competitively inhibit MAO B with Ki values
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca296714ce57182c81eb09c579acf37d
https://doi.org/10.1021/jm070677y
https://doi.org/10.1021/jm070677y
Autor:
Elio Polli, Caterina Pati, Maria Grazia Tripodi, Giuseppe Bianchi, Cristian Barlassina, E. Niutta, Ettore Guidi, Patricia Salvati, Patrizia Ferrari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b123f92fa529dd402c17ebc98ca54f6f
https://doi.org/10.1159/000411911
https://doi.org/10.1159/000411911
Autor:
S. Maestroni, Ruggero Fariello, Carla Caccia, L. Faravelli, M Calabresi, Roberto Maj, Patricia Salvati, L. Curatolo
Publikováno v:
Neurology. 67:S18-S23
Ideal treatment in Parkinson's disease (PD) aims at relieving symptoms and slowing disease progression. Of all remedies, levodopa remains the most effective for symptomatic relief, but the medical need for neuroprotectant drugs is still unfulfilled.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce3a072ad5c728c8938608b092c9046
https://doi.org/10.1212/wnl.67.7_suppl_2.s18
https://doi.org/10.1212/wnl.67.7_suppl_2.s18
Publikováno v:
Expert Opinion on Investigational Drugs. 13:1249-1261
Chronic pain affects a large percentage of the population, representing a socio-economic burden. Current treatments are characterised by suboptimal efficacy and/or side effects that limit their use. Among several approaches to treating chronic pain,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee9a5cee35409246354dada126814a63
https://doi.org/10.1517/13543784.13.10.1249
https://doi.org/10.1517/13543784.13.10.1249
Publikováno v:
Pain. 102:17-25
NW-1029, a benzylamino propanamide derivative, was selected among several molecules of this chemical class on the basis of its affinity for the [(3)H]batracotoxin ligand displacement of the Na(+) channel complex and also on the basis of its voltage a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5218e9c9ad4e4dcc27a6459f553f33
https://doi.org/10.1016/s0304-3959(02)00183-5
https://doi.org/10.1016/s0304-3959(02)00183-5
Autor:
Patricia Salvati, Roberto Maj, Paolo Pevarello, Robert A. McArthur, Mario Varasi, Ruggero Fariello
Publikováno v:
Epilepsia. 40:1523-1528
Summary: Purpose: PNU-151774E [(S)-(+)-2-(4-(3-fluoro-benzyloxy) benzylamino) propanamide, methanesulfonate] is a novel antiepileptic drug (AED) with a broad spectrum of activity in a variety of chemically and mechanically induced seizures. The objec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7162f5449a77110ebf998f0e4872116e
https://doi.org/10.1111/j.1528-1157.1999.tb02035.x
https://doi.org/10.1111/j.1528-1157.1999.tb02035.x
Autor:
Ernesto Lamberti, Laura Chiodini, Enzo Brambilla, Daniela Ruggieri, Sergio Mantegani, Carla Caccia, Patricia Salvati, Enrico Di Salle
Publikováno v:
Il Farmaco. 53:293-304
The synthesis and antihypertensive activity of a series of 2,4-dioxoimidazolidin-1-yl and perhydro-2,4-dioxopyrimidin-1-yl ergoline derivatives are reported. The oral antihypertensive activity was studied in spontaneously hypertensive rats (SHRs) by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1cd298a198f9dd6927be180f0be377
https://doi.org/10.1016/s0014-827x(98)00023-8
https://doi.org/10.1016/s0014-827x(98)00023-8
Autor:
Patricia Salvati, Giorgio Ukmar, Peter J. Schwartz, Carlo Patrono, Gaetano M. De Ferrari, Lorenzo Vaga, Mauro Grossoni
Publikováno v:
Journal of the American College of Cardiology. 22(1):283-290
Objectives. The goal of the present study was to evaluate the antifibrillatory and hemodynamic effects of pharmacologic muscarinic activation and to compare them with those of beta-adrenergic blockade. Background. Recent studies suggest a correlation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::544e9f5395fa0f29414f7d59c3d40c4b