Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Patricia Saiz-Lopez"'
Autor:
Sofia Sedas Perez, Caitlin McQueen, Holly Stainton, Joseph Pickering, Kavitha Chinnaiya, Patricia Saiz-Lopez, Marysia Placzek, Maria A. Ros, Matthew Towers
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Complex signalling between the apical ectodermal ridge (AER - a thickening of the distal epithelium) and the mesoderm controls limb patterning along the proximo-distal axis (humerus to digits). However, the essential in vivo requirement for
Externí odkaz:
https://doaj.org/article/e210d06c502c48f095a84e784793b84f
Autor:
Joseph Pickering, Constance A Rich, Holly Stainton, Cristina Aceituno, Kavitha Chinnaiya, Patricia Saiz-Lopez, Marian A Ros, Matthew Towers
Publikováno v:
eLife, Vol 7 (2018)
The longstanding view of how proliferative outgrowth terminates following the patterning phase of limb development involves the breakdown of reciprocal extrinsic signalling between the distal mesenchyme and the overlying epithelium (e-m signalling).
Externí odkaz:
https://doaj.org/article/e79a171bc9d540da8cd39b6e1b85e038
Autor:
Joseph Pickering, Marian A Ros, Constance A Rich, Patricia Saiz-Lopez, Matthew Towers, Cristina Aceituno, Holly Stainton, Kavitha Chinnaiya
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c4cf1416dee90e66059fafb793d7cf8
https://doi.org/10.7554/elife.37429.022
https://doi.org/10.7554/elife.37429.022
Autor:
Kavitha Chinnaiya, Joseph Pickering, Patricia Saiz-Lopez, Marian A Ros, Matthew Towers, Constance A Rich
The longstanding view of how proliferative outgrowth terminates following the patterning phase of limb development involves the breakdown of reciprocal extrinsic signalling between the mesenchyme and the overlying epithelium (e-m signalling). However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5612a4a6f113cc36b5d07d3af110554
https://doi.org/10.1101/296350
https://doi.org/10.1101/296350
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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An intrinsic timing mechanism specifies the positional values of the zeugopod (i.e. radius/ulna) and then autopod (i.e. wrist/digits) segments during limb development. Here, we have addressed whether this timing mechanism ensures that patterning even