Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Patricia Saenz-Méndez"'
Publikováno v:
ACS Omega, Vol 2, Iss 4, Pp 1710-1719 (2017)
Externí odkaz:
https://doaj.org/article/c8e09c3e8345452ab824ea34f28af1e2
Publikováno v:
Molecules, Vol 21, Iss 3, p 351 (2016)
A new CYP26A1 homology model was built based on the crystal structure of cyanobacterial CYP120A1. The model quality was examined for stereochemical accuracy, folding reliability, and absolute quality using a variety of different bioinformatics tools.
Externí odkaz:
https://doaj.org/article/6152ba14d8e3495c98ba57e7a01fec65
Autor:
Ali Ateia Elmabsout, Ashok Kumawat, Patricia Saenz-Méndez, Olesya Krivospitskaya, Helena Sävenstrand, Peder S Olofsson, Leif A Eriksson, Ake Strid, Guro Valen, Hans Törmä, Allan Sirsjö
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36839 (2012)
All-trans retinoic acid (atRA) plays an essential role in the regulation of gene expression, cell growth and differentiation and is also important for normal cardiovascular development but may in turn be involved in cardiovascular diseases, i.e. athe
Externí odkaz:
https://doaj.org/article/4f03da3133304ea7b8774c766c32f95f
Autor:
Cecilia Porciúncula González, Carolina Fontana, Karina Mariño, Alejandro J. Cagnoni, Cecilia Giacomini, Gabriela Irazoqui, Patricia Saenz-Méndez
Publikováno v:
Carbohydrate Research. 472:1-15
Galectins are a family of carbohydrate-recognizing proteins that by interacting with specific glycoepitopes can mediate important biological processes, including immune cell homeostasis and activation of tolerogenic circuits. Among the different memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e1e7f03da87d02990663a348e1769cd
https://doi.org/10.1016/j.carres.2018.10.011
https://doi.org/10.1016/j.carres.2018.10.011
Autor:
Karina Mariño, Cecilia Giacomini, Gabriela Irazoqui, Cecilia Porciúncula-González, Patricia Saenz-Méndez, Alejandro J. Cagnoni, Carolina Fontana
Publikováno v:
Bioorganicmedicinal chemistry. 44
Galectins, soluble lectins widely expressed intra- and extracellularly in different cell types, play major roles in deciphering the cellular glycocode. Galectin-1 (Gal-1), a prototype member of this family, presents a carbohydrate recognition domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6162208e3dbac79f2dcccd287e1e27
https://pubmed.ncbi.nlm.nih.gov/34293617
https://pubmed.ncbi.nlm.nih.gov/34293617
Autor:
Reshma Srilakshmi Rudraraju, Elton P. Hudson, Antonino Biundo, Per-Olof Syrén, Karen Schriever, Natalie M. Hendrikse, Robert Schnell, Patricia Saenz-Méndez
Publikováno v:
Journal of the American Chemical Society
Structural information is crucial for understanding catalytic mechanisms and to guide enzyme engineering efforts of biocatalysts, such as terpene cyclases. However, low sequence similarity can impede homology modeling, and inherent protein instabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fac93902780f652b58286cc36ac363b9
http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-83516
http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-83516
Autor:
Azizeh Abdolmaleki, Imlimaong Aier, Carolina Horta Andrade, Tamanna Anwar, Hemant Arya, Tarun Kumar Bhatt, Andrzej J. Bojarski, Francesca Cavaliere, Sibani Sen Chakraborty, Jeyaraj Pandian Chitra, José Correa-Basurto, Mohane Selvaraj Coumar, Pietro Cozzini, R. Vasundhara Devi, Teodora Djikic, Zarko Gagic, Jahan B. Ghasemi, Divya Gupta, Ravi Guru Raj Rao, Sapna Jain, Jeyaraman Jeyakanthan, Asad U. Khan, Sree Karani Kondapuram, Pawan Kumar, Nathalie Lagarde, Florent Langenfeld, Neeraj Mahindroo, Sabrina Silva Mendonca, Matthieu Montes, José Teofilo Moreira-Filho, Melina Mottin, Ayaluru Murali, Mutharasappan Nachiappan, Bruno Junior Neves, Katarina Nikolic, Sourav Pal, Archana Pan, Jeevan Patra, Sabina Podlewska, Dhamodharan Prabhu, G. Pranavathiyani, Sundarraj Rajamanikandan, Muthukumaran Rajagopalan, Amutha Ramaswamy, Manon Réau, Mariadasse Richard, Patricia Saenz-Méndez, Balasubramanian Sangeetha, Sailu Sarvagalla, Daniela Schuster, Thomas Scior, Asma Sellami, Fereshteh Shiri, Deepanmol Singh, Yudibeth Sixto-López, Bruna Katiele de Paula Sousa, Giulia Spaggiari, Arindam Talukdar, Veronika Temml, Pritish Kumar Varadwaj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3dcff99dbd3224495d2d7306fafffc4
https://doi.org/10.1016/b978-0-12-822312-3.01002-x
https://doi.org/10.1016/b978-0-12-822312-3.01002-x
Autor:
Patricia Saenz-Méndez
This chapter discusses the change in the paradigm of drug discovery, shifting from the “magic bullet” concept to the “magic shotgun” or “silver bullet” approach, i.e., one-compound—multiple-target model. The concept of polypharmacology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f18e6f62bc26d342b4bbca627ea76548
https://doi.org/10.1016/b978-0-12-822312-3.00005-9
https://doi.org/10.1016/b978-0-12-822312-3.00005-9
Publikováno v:
Journal of Molecular Structure. 1146:1-4
A first principles simulation of the crystal structure of potassium peroxocarbonate is presented, using density functional methods (both local and semilocal) for the calculations. An experimental crystal structure with a seemingly inconsistent dispos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::382410e85ffc26cb1dfa2bb2d5ae9fa4
https://doi.org/10.1016/j.molstruc.2017.05.115
https://doi.org/10.1016/j.molstruc.2017.05.115
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 85:1983-1993
RtcB is an essential human tRNA ligase required for ligating the 2',3'-cyclic phosphate and 5'-hydroxyl termini of cleaved tRNA halves during tRNA splicing and XBP1 fragments during endoplasmic reticulum stress. Activation of XBP1 has been implicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5273718fbf50820031670490ca7d78dd
https://doi.org/10.1002/prot.25352
https://doi.org/10.1002/prot.25352