Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Patricia S. Holman"'
Publikováno v:
Journal of Biological Chemistry. 272:22300-22306
Activation of the Cdc2.cyclin B kinase is a pivotal step of mitotic initiation. This step is mediated principally by the dephosphorylation of residues threonine 14 (Thr14) and tyrosine 15 (Tyr15) on the Cdc2 catalytic subunit. In several organisms ho
Publikováno v:
Proceedings of the National Academy of Sciences. 91:12125-12129
Polyoma large T antigen (LT) is the only viral gene product required for viral DNA replication. LT can be divided into two domains, one N-terminal (NT) spanning residues 1-260 and one C-terminal (CT) comprising approximately residues 264-785. NT is k
Autor:
Helen C. Poynton, Giorgio Cavigiolio, Elizabeth C. Theil, Owen Hughes, Sarah Chan, Alexandre Loguinov, Darren J. Bauer, Kelly Komachi, Julia R. Varshavsky, Edward J. Perkins, Chris D. Vulpe, Patricia S. Holman, Bonnie Chang
Publikováno v:
Environmental sciencetechnology. 41(3)
Toxicogenomics has provided innovative approaches to chemical screening, risk assessment, and predictive toxicology. If applied to ecotoxicology, genomics tools could greatly enhance the ability to understand the modes of toxicity in environmentally
Autor:
Christopher J. Green, Dean R. Tolan, Joshua Niclas, Patricia S. Holman, Tom Camerato, Kelly R Deselms, William H. Rottmann
Publikováno v:
Biochimie. 69:137-145
The complete protein sequence of the human aldolase C isozyme has been determined from recombinant genomic clones. A genomic fragment of 6673 base pairs was isolated and the DNA sequence determined. Aldolase protein sequences, being highly conserved,