Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Patricia S. Fletcher"'
Autor:
Patricia S. Fletcher, Ettore Appella, Ryo Hayashi, Marco Schito, A. Robert Neurath, Robin J. Shattock, Lisa M. Miller Jenkins, Cecilia Cheng-Mayer, Gregory S. Wallace
Publikováno v:
Journal of Virology. 83:9175-9182
Here, we report that the S -acyl-2-mercaptobenzamide thioester (SAMT) class of human immunodeficiency virus type 1 (HIV-1) nucleocapsid protein (NCp7) inhibitors was able to prevent transmission of HIV-1 from infected cells, including primary cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f82e9ada00869357ba704b8e03225a
https://doi.org/10.1128/jvi.00820-09
https://doi.org/10.1128/jvi.00820-09
Autor:
Robin J. Shattock, Sarah Harman, Hilde Azijn, Jeremy Nuttall, P. Manlow, D. Perumal, MP de Béthune, Naomi Armanasco, Joseph Romano, Patricia S. Fletcher
Publikováno v:
Antimicrobial Agents and Chemotherapy. 53:487-495
Heterosexual transmission of human immunodeficiency virus (HIV) remains the major route of infection worldwide; thus, there is an urgent need for additional prevention strategies, particularly strategies that could be controlled by women, such as top
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b2a32700b297e8611c1c5a200c795b
https://doi.org/10.1128/aac.01156-08
https://doi.org/10.1128/aac.01156-08
Autor:
Peter A. Anton, Julie Elliott, Ian McGowan, Patricia S. Fletcher, Robin J. Shattock, Jean-Charles Grivel, Leonid Margolis
Publikováno v:
AIDS. 20:1237-1245
Objectives Establishment of an in vitro model to evaluate rectal safety and the efficacy of microbicide candidates. Design An investigation and characterization of human colorectal explant culture for screening candidate microbicides to prevent recta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feac42c71bf304723cbebd4818534877
https://doi.org/10.1097/01.aids.0000232230.96134.80
https://doi.org/10.1097/01.aids.0000232230.96134.80
Publikováno v:
BJU International. 97:1043-1046
OBJECTIVE To investigate whether a range of cytokines were detectable in the seminal plasma and urine of men with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and nonspecific urethritis (NSU), and whether cytokine levels correlated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74da2dc3bc33ee26938ce42e9c14c7a4
https://doi.org/10.1111/j.1464-410x.2006.06133.x
https://doi.org/10.1111/j.1464-410x.2006.06133.x
Autor:
Luke A. Pallansch, Ena Bromley, Mary K. Howett, Brigitte E. Beer, Patricia A. Welsh, Robert W. Buckheit, Brian Wigdahl, Nicola Richardson-Harman, Bradley J. Catalone, Carol Lackman-Smith, Fred C. Krebs, Shendra R. Miller, Gustavo F. Doncel, Clay Osterling, Robin J. Shattock, Karen M. Watson, Jim A. Turpin, James E. Cummins, Charlene S. Dezzutti, Patricia Reichelderfer, Marie K. Mankowski, Patricia S. Fletcher
Publikováno v:
Antimicrobial Agents and Chemotherapy. 50:713-723
The first product to be clinically evaluated as a microbicide contained the nonionic surfactant nonoxynol-9 (nonylphenoxypolyethoxyethanol; N-9). Many laboratories have used N-9 as a control compound for microbicide assays. However, no published comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71945f46c22cf2a64a2b867425893553
https://doi.org/10.1128/aac.50.2.713-723.2006
https://doi.org/10.1128/aac.50.2.713-723.2006
Autor:
Muddagowda Umashankara, Kantharaju, Julio Martín-García, Srivats Rajagopal, Hosahudya N. Gopi, Patricia S. Fletcher, Fiorella Rossi, Irwin Chaiken, Fred C. Krebs, Robin J. Shattock, Vanessa Pirrone, Karyn McFadden
Publikováno v:
Antimicrobial agents and chemotherapy. 56(2)
The first stage of human immunodeficiency virus type 1 (HIV-1) infection involves the fusion of viral and host cellular membranes mediated by viral envelope glycoprotein gp120. Inhibitors that specifically target gp120 are gaining increased attention
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847fec6f4ec02ab46211fe03857351e7
https://pubmed.ncbi.nlm.nih.gov/22083481
https://pubmed.ncbi.nlm.nih.gov/22083481
Autor:
Patricia S. Fletcher, Naomi Armanasco, N Almond, K DaCosta, William Elsley, Martin Cranage, Paul F. McKay, Mark Page, Alethea Cope, AN Mahmoud, C. Fraser, Robin J. Shattock
Publikováno v:
Retrovirology, Vol 6, Iss Suppl 3, p P151 (2009)
Retrovirology
Retrovirology
Background Vaccine-mediated prevention of primary infection with HIV likely requires the sustained production of antibody at mucosal portals of entry. We determined the dynamics of systemic and mucosal antibody production in macaques following a nove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38f9141a24e2dc7baf002b146eedc30
https://doi.org/10.1186/1742-4690-6-s3-p151
https://doi.org/10.1186/1742-4690-6-s3-p151
Autor:
Patricia C. Guenthner, Jean-Charles Grivel, Phalguni Gupta, Paula Roberts, Nicola Richardson-Harman, Leonid Margolis, Robin J. Shattock, Charlene S. Dezzutti, Peter A. Anton, James E. Cummins, James W. Bremer, Patricia Reichelderfer, Swarna Mohan, Nell S. Lurain, Julie Elliott, Maureen Jones, Deena Ratner, Patricia S. Fletcher, Carol Lackman-Smith
Microbicide candidates with promising in vitro activity are often advanced for evaluations using human primary tissue explants relevant to the in vivo mucosal transmission of human immunodeficiency virus type 1 (HIV-1), such as tonsil, cervical, or r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf0c54e4eeb051e43bcff963eacf80cc
https://europepmc.org/articles/PMC2772583/
https://europepmc.org/articles/PMC2772583/
Publikováno v:
Current opinion in investigational drugs (London, England : 2000). 9(2)
Indevus Pharmaceuticals Inc, under license from Paligent Inc, is developing PRO-2000, an antimicrobial gel for the prevention of HIV infection. The company is also investigating its potential to prevent the transmission of other sexually transmitted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::15be415840353b23aebef1612fccb055
https://pubmed.ncbi.nlm.nih.gov/18246522
https://pubmed.ncbi.nlm.nih.gov/18246522
Publikováno v:
Retrovirology
Retrovirology, Vol 3, Iss 1, p 46 (2006)
Retrovirology, Vol 3, Iss 1, p 46 (2006)
Background Heterosexual intercourse remains the major route of HIV-1 transmission worldwide, with almost 5 million new infections occurring each year. Women increasingly bear a disproportionate burden of the pandemic, thus there is an urgent need to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b658946d53c9d005127b13286a2662ae
https://openaccess.sgul.ac.uk/id/eprint/1267/1/1742-4690-3-46.pdf
https://openaccess.sgul.ac.uk/id/eprint/1267/1/1742-4690-3-46.pdf