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Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 9 (2020)
Mouse models of Down syndrome (DS) have been invaluable tools for advancing knowledge of the underlying mechanisms of intellectual disability in people with DS. The Ts(1716)65Dn (Ts65Dn) mouse is one of the most commonly used models as it recapitulat
Externí odkaz:
https://doaj.org/article/61f4148cd77046ca8aeed53a7a8176bd
Autor:
Tarik F. Haydar, Patricia R. Shaw
Publikováno v:
Neuron
Summary Microglia are brain-resident immune cells and regulate mechanisms essential for cognitive functions. Down syndrome (DS), the most frequent cause of genetic intellectual disability, is caused by a supernumerary chromosome 21, containing also g
Publikováno v:
Disease Models & Mechanisms
article-version (VoR) Version of Record
Disease Models & Mechanisms, Vol 13, Iss 9 (2020)
article-version (VoR) Version of Record
Disease Models & Mechanisms, Vol 13, Iss 9 (2020)
Mouse models of Down syndrome (DS) have been invaluable tools for advancing knowledge of the underlying mechanisms of intellectual disability in people with DS. The Ts(1716)65Dn (Ts65Dn) mouse is one of the most commonly used models as it recapitulat