Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Patricia R, Jusuf"'
Autor:
Kellie Veen, Aaron Krylov, Shuguang Yu, Jie He, Patrick Boyd, David R Hyde, Theo Mantamadiotis, Louise Y Cheng, Patricia R Jusuf
Publikováno v:
PLoS Genetics, Vol 19, Iss 11, p e1011010 (2023)
Damage to light-sensing photoreceptors (PRs) occurs in highly prevalent retinal diseases. As humans cannot regenerate new PRs, these diseases often lead to irreversible blindness. Intriguingly, animals, such as the zebrafish, can regenerate PRs effic
Externí odkaz:
https://doaj.org/article/8ef06266d87844008623f8c29ba51dad
Autor:
Aaron Krylov, Shuguang Yu, Kellie Veen, Axel Newton, Aojun Ye, Huiwen Qin, Jie He, Patricia R. Jusuf
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
IntroductionLoss of neurons in the neural retina is a leading cause of vision loss. While humans do not possess the capacity for retinal regeneration, zebrafish can achieve this through activation of resident Müller glia. Remarkably, despite the pre
Externí odkaz:
https://doaj.org/article/a2b5e21015a1443e856c807021606971
Autor:
Melanie K. Stewart, Luca Hoehne, Stefanie Dudczig, Deidre M. Mattiske, Andrew J. Pask, Patricia R. Jusuf
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 251, Iss , Pp 114541- (2023)
Endocrine disrupting chemicals (EDCs) can interact with native hormone receptors to interfere with and disrupt hormone signalling that is necessary for a broad range of developmental pathways. EDCs are pervasive in our environment, in particular in o
Externí odkaz:
https://doaj.org/article/b3818036827e48e3a9f7a37f3565a129
Autor:
Akhtar Ali, Sarah M. Kiloni, Paolin R. Cáceres-Vélez, Patricia R. Jusuf, Jeremy J. Cottrell, Frank R. Dunshea
Publikováno v:
Foods, Vol 11, Iss 24, p 4038 (2022)
Phytochemicals play a pivotal role in human health and drug discovery. The safety evaluation of plant extracts is a prerequisite to ensure that all phytochemicals are safe before translational development and human exposure. As phytochemicals are nat
Externí odkaz:
https://doaj.org/article/cf188e48faf249c79f23c1bf8bec72ec
Autor:
Yona Goldshmit, Jean Kitty K. Y. Tang, Ashley L. Siegel, Phong D. Nguyen, Jan Kaslin, Peter D. Currie, Patricia R. Jusuf
Publikováno v:
Neural Development, Vol 13, Iss 1, Pp 1-14 (2018)
Abstract Background Despite conserved developmental processes and organization of the vertebrate central nervous system, only some vertebrates including zebrafish can efficiently regenerate neural damage including after spinal cord injury. The mammal
Externí odkaz:
https://doaj.org/article/fbd21fe2995541b3884b3cc6e2f33a1b
Autor:
Kellie Veen, Phuong‐Khanh Nguyen, Francesca Froldi, Qian Dong, Edel Alvarez‐Ochoa, Kieran F Harvey, John PD McMullen, Owen Marshall, Patricia R Jusuf, Louise Y Cheng
Publikováno v:
EMBO reports.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01832e67261854fc1596f9d4a4348b09
https://doi.org/10.15252/embr.202255837
https://doi.org/10.15252/embr.202255837
Loss of neurons in the neural retina is a leading cause of vision loss. While humans do not possess the capacity for retinal regeneration, zebrafish can achieve this through activation of resident Müller glia. Remarkably, despite the presence of Mü
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1cf857a9b0b0d149cbd987bdda35a2a
https://doi.org/10.1101/2023.01.27.525802
https://doi.org/10.1101/2023.01.27.525802
Autor:
Christoph Krisp, Carmen Sonntag, L. Hersey, A.J. Wood, Sara Gibertini, Alex J. Fulcher, Patricia R. Jusuf, A. Siegel, Marina Mora, Chi-Hung Lin, Peter D. Currie, Stefanie Dudczig, Sara Alaei, Nicolle H. Packer, M. Li, K. Nishtala, Lee B. Miles, Paul J. Conroy, Fernando J. Rossello
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
The muscular dystrophies encompass a broad range of pathologies with varied clinical outcomes. In the case of patients carrying defects in fukutin-related protein (FKRP), these diverse pathologies arise from mutations within the same gene. This is su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67cabdaabec93cd531c0cf30e6b95309
https://doaj.org/article/5e6f8208fa384dfab7d8162c046eec48
https://doaj.org/article/5e6f8208fa384dfab7d8162c046eec48
Autor:
Kellie Veen, Francesca Froldi, Qian Dong, Edel Alvarez-Ochoa, Phuong-Khanh Nguyen, Kieran F Harvey, John P D McMullen, Owen Marshall, Patricia R Jusuf, Louise Y Cheng
Dedifferentiation is the reversion of differentiated cells to a stem cell like fate, whereby, the gene expression program of mature cells is altered and genes associated with multipotency are expressed. Appropriate terminal differentiation of NSCs is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ff33a9b7f46e6c6d05741470aaabd32
https://doi.org/10.1101/2022.07.24.501087
https://doi.org/10.1101/2022.07.24.501087
The human PDZK1 gene is located in a genomic susceptibility region for neurodevelopmental disorders. A genome-wide association study (GWAS) identified links between PDZK1 polymorphisms and altered visual contrast sensitivity, an endophenotype for sch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38ee44137aad8f2f3af419b79ee0fa01
https://doi.org/10.1101/2020.09.21.307405
https://doi.org/10.1101/2020.09.21.307405