Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Patricia Perez Galan"'
Autor:
Cédric Rossi, Pauline Gravelle, Emilie Decaup, Julie Bordenave, Mary Poupot, Marie Tosolini, Don-Marc Franchini, Camille Laurent, Renaud Morin, Jean-Michel Lagarde, Loïc Ysebaert, Laetitia Ligat, Christine Jean, Ariel Savina, Christian Klein, Alba Matas Céspedes, Patricia Perez-Galan, Jean-Jacques Fournié, Christine Bezombes
Publikováno v:
OncoImmunology, Vol 8, Iss 3 (2019)
Follicular lymphoma (FL) is a common non Hodgkin’s lymphoma subtype in which immune escape mechanisms are implicated in resistance to chemo-immunotherapy. Although molecular studies point to qualitative and quantitative deregulation of immune check
Externí odkaz:
https://doaj.org/article/a8db99156a06463dae6814c1f88e05ab
Autor:
Javier Garcia Fernandez, Anna Warnecke, Serghei Chercheja, Heidi-Kristin Walter, Lara Pes, Felix Kratz, Federico Medda, Friederike I. Nollmann, Didier Rognan, Steffen Daum, Khalid Abu Ajaj, Patricia Perez Galan, Magnusson Johannes Pall, Koester Stephan David
Publikováno v:
Journal of Controlled Release. 296:81-92
Auristatins are a class of highly cytotoxic tubulin-disrupting peptides, which have shown limited therapeutic effect as free agents in clinical trials. In our continuing effort to develop acid-sensitive albumin-binding anticancer drugs exploiting cir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc3b07851396b9736b65ff1737d620a1
https://doi.org/10.1016/j.jconrel.2019.01.010
https://doi.org/10.1016/j.jconrel.2019.01.010
Autor:
Neus Gimenez, Rupal Tripathi, Ariadna Giró, Laia Rosich, Mònica López-Guerra, Irene Lopez-Oreja, Heribert Playa-Albinyana, Fabian Arenas, José Manuel Mas, Patricia Perez-Galan, Julio Delgado, Elias Campo, Judith Farrés, Dolors Colomer
Background: Chronic lymphocytic leukemia (CLL) is a B lymphoid malignancy highly dependent on the microenvironment. CLL cell interactions with the supportive tissue microenvironment play a critical role in disease pathogenesis. Despite new targeted t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ffcbb43edebbbf30d353fa14121c3be
https://doi.org/10.21203/rs.3.rs-50232/v1
https://doi.org/10.21203/rs.3.rs-50232/v1
Autor:
Felix Kratz, Federico Medda, Javier Garcia Fernandez, Heidi-Kristin Walter, Serghei Chercheja, Anna Warnecke, Lara Pes, Patricia Perez Galan, Magnusson Johannes Pall, Friederike I. Nollmann, Khalid Abu Ajaj, Koester Stephan David
Publikováno v:
Cancer Research. 78:3703-3703
Auristatins are highly cytotoxic antimitotic tubulin-binding peptides. Of this family, only Adcetris®, an antibody drug conjugate (ADC) derived from monomethyl auristatin E (MMAE), is approved and marketed. Other auristatins such as dolastatin 10, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7469cf806f1784d973caebf1dfe7eef
https://doi.org/10.1158/1538-7445.am2018-3703
https://doi.org/10.1158/1538-7445.am2018-3703
Autor:
Felix Kratz, Federico Medda, Javier Garcia Fernandez, Heidi K. Walter, Friederike I. Nollmann, Lara Pes, Magnusson Johannes Pall, Koester Stephan David, Patricia Perez Galan, Khalid Abu Ajaj, Serghei Chercheja, Anna Warnecke
Publikováno v:
Cancer Research. 78:1657-1657
Introduction and objectives: Maytansine and its analogs (DM1 and DM4) are potent microtubule-targeting compounds that inhibit proliferation of cells during mitosis.1 Unfortunately, their narrow therapeutic window prevents a clinical application of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::466f9ca4145cfa741a9f3a066beaeb70
https://doi.org/10.1158/1538-7445.am2018-1657
https://doi.org/10.1158/1538-7445.am2018-1657
Autor:
Javier Garcia Fernandez, Lara Pes, Heidi K. Walter, Friederike I. Nollmann, Federico Medda, Magnusson Johannes Pall, Felix Kratz, Anna Warnecke, Koester Stephan David, Serghei Chercheja, Patricia Perez Galan, Khalid Abu Ajaj
Publikováno v:
Cancer Research. 78:2661-2661
Introduction and objectives: Maytansine and its analogs (DM1 and DM4) are potent microtubule-targeting compounds that inhibit proliferation of cells during mitosis. Their potent anticancer activity made them attractive for drug development.1 Unfortun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f3ca8028e33eeb29be5711cb138dc59
https://doi.org/10.1158/1538-7445.am2018-2661
https://doi.org/10.1158/1538-7445.am2018-2661
Autor:
Patricia Perez‐Galan, Elena Herrero-Gómez, Antonio M. Echavarren, Salomé López, Cristina Nieto-Oberhuber
Publikováno v:
Angewandte Chemie. 118:6175-6178
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2830543cbab660bb4e557833f219db77
https://doi.org/10.1002/ange.200602448
https://doi.org/10.1002/ange.200602448
Akademický článek
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Autor:
Patricia Perez‐Galan, Mihai Raducan, Catalina Ferrer, Verónica López-Carrillo, Antonio M. Echavarren, Catelijne H. M. Amijs
Publikováno v:
ChemInform. 40
Gold(I)-catalyzed addition of carbon nucleophiles to 1,6-enynes gives two different type of products by reaction at the cyclopropane or at the carbene carbons of the intermediate cyclopropyl gold carbenes. The 5-exo-dig cyclization is followed by mos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfa164f5f396ea5da46a8e919005e055
https://doi.org/10.1002/chin.200907035
https://doi.org/10.1002/chin.200907035
Autor:
Antonio M. Echavarren, Patricia Perez‐Galan, Catalina Ferrer, Catelijne H. M. Amijs, Mihai Raducan, Verónica López-Carrillo
Publikováno v:
The Journal of organic chemistry. 73(19)
Gold(I)-catalyzed addition of carbon nucleophiles to 1,6-enynes gives two different type of products by reaction at the cyclopropane or at the carbene carbons of the intermediate cyclopropyl gold carbenes. The 5-exo-dig cyclization is followed by mos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94461c38a5546622e287eebfc65db33e
https://pubmed.ncbi.nlm.nih.gov/18759485
https://pubmed.ncbi.nlm.nih.gov/18759485