Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Patricia P Chan"'
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134738 (2015)
The rat kangaroo (long-nosed potoroo, Potorous tridactylus) is a marsupial native to Australia. Cultured rat kangaroo kidney epithelial cells (PtK) are commonly used to study cell biological processes. These mammalian cells are large, adherent, and f
Externí odkaz:
https://doaj.org/article/9d7ac074267f409d96d0d16a94d11167
Autor:
Halie K Miller, Laura Kwuan, Leah Schwiesow, David L Bernick, Erin Mettert, Hector A Ramirez, James M Ragle, Patricia P Chan, Patricia J Kiley, Todd M Lowe, Victoria Auerbuch
Publikováno v:
PLoS Pathogens, Vol 10, Iss 6, p e1004194 (2014)
Type III secretion systems (T3SS) are essential for virulence in dozens of pathogens, but are not required for growth outside the host. Therefore, the T3SS of many bacterial species are under tight regulatory control. To increase our understanding of
Externí odkaz:
https://doaj.org/article/fb54df826ac34313a2133f448d366815
Autor:
Andrew D. Holmes, Patricia P. Chan, Qi Chen, Pavel Ivanov, Laurence Drouard, Norbert Polacek, Mark A. Kay, Todd M. Lowe
Small RNAs processed from transfer RNA are recognized to have regulatory functions distinct from protein synthesis. This rapidly advancing field has led to a constellation of transcript nomenclatures. Building upon the accepted tRNA naming system and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::514e57aea0374e987516be0130b4fee8
Recent high-throughput sequencing protocols have facilitated increased accuracy in measurements of transfer tRNAs (tRNAs) and tRNA-derived small RNAs (tDRs) from biological samples. However, commonly used RNA-seq analysis pipelines overlook special c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e83959e2ac3b7ba0fb2b12127469fe1
https://doi.org/10.1101/2022.07.02.498565
https://doi.org/10.1101/2022.07.02.498565
Publikováno v:
Nucleic acids research. 50(7)
Metazoan organisms have many tRNA genes responsible for decoding amino acids. The set of all tRNA genes can be grouped in sets of common amino acids and isoacceptor tRNAs that are aminoacylated by corresponding aminoacyl-tRNA synthetases. Analysis of
Publikováno v:
microPublication biology. 2022
Transfer RNAs (tRNAs) are ubiquitous adapter molecules that link specific codons in messenger RNA (mRNA) with their corresponding amino acids during protein synthesis. The tRNA genes of Drosophila have been investigated for over half a century but ha
Autor:
Guoping Li, Aidan C. Manning, Alex Bagi, Xinyu Yang, Priyanka Gokulnath, Michail Spanos, Jonathan Howard, Patricia P. Chan, Thadryan Sweeney, Robert Kitchen, Haobo Li, Brice D. Laurent, Sary F. Aranki, Maria I. Kontaridis, Louise C. Laurent, Kendall Van Keuren‐Jensen, Jochen Muehlschlegel, Todd M. Lowe, Saumya Das
Publikováno v:
Advanced science (Weinheim, Baden-Wurttemberg, Germany). 9(17)
The cellular response to stress is an important determinant of disease pathogenesis. Uncovering the molecular fingerprints of distinct stress responses may identify novel biomarkers and key signaling pathways for different diseases. Emerging evidence
Autor:
Brice D. Laurent, Haobo Li, Robert R. Kitchen, Aidan Manning, Maria I. Kontaridis, Alex Bagi, Todd M. Lowe, Xinyu Yang, Guoping Li, Jonathan M. Howard, Jochen D. Muehlschlegel, Thadryan Sweeney, Saumya Das, Patricia P. Chan, Louise C. Laurent, Kendall Van Keuren Jensen, Sary F. Aranki
SUMMARYThe cellular response to stress is an important determinant of disease pathogenesis. Uncovering the molecular fingerprints of distinct stress responses may yield novel biomarkers for different diseases, and potentially identify key signaling p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e4c3a274f176c12c1b8e37a8a6f7252
https://doi.org/10.1101/2021.09.03.458085
https://doi.org/10.1101/2021.09.03.458085
Publikováno v:
Nucleic Acids Research
Transfer RNAs (tRNAs) are ubiquitous across the tree of life. Although tRNA structure is highly conserved, there is still significant variation in sequence features between clades, isotypes and even isodecoders. This variation not only impacts transl
Autor:
Eric P. Nawrocki, Aparna Maddala, Jamie J. Cannone, Robin R. Gutell, Patricia P. Chan, Todd M. Lowe, Blake A. Sweeney, Anton I. Petrov, Caeden D. Meade, David Hoksza, Carlos Eduardo Ribas, Robert D. Finn, Loren Dean Williams, Anton S. Petrov, Fábio Madeira
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Non-coding RNAs (ncRNA) are essential for all life, and their functions often depend on their secondary (2D) and tertiary structure. Despite the abundance of software for the visualisation of ncRNAs, few automatically generate consistent and recognis