Nmf9 Encodes a Highly Conserved Protein Important to Neurological Function in Mice and Flies.

Autor: Shuxiao Zhang, Kevin D Ross, Glen A Seidner, Michael R Gorman, Tiffany H Poon, Xiaobo Wang, Elizabeth M Keithley, Patricia N Lee, Mark Q Martindale, William J Joiner, Bruce A Hamilton

Publikováno v: PLoS Genetics, Vol 11, Iss 7, p e1005344 (2015)

Many protein-coding genes identified by genome sequencing remain without functional annotation or biological context. Here we define a novel protein-coding gene, Nmf9, based on a forward genetic screen for neurological function. ENU-induced and genom

Externí odkaz: https://doaj.org/article/6c6d31be1630485ab0f0fc1d9298e7cd

The Development of Form: Causes and Consequences of Developmental Reprogramming Associated with Rapid Body Plan Evolution in the Bilaterian Radiation

Autor: Patricia N. Lee, Mark Q. Martindale

Publikováno v: Biological Theory. 8:253-264

Organismal form arises by the coordinated movement, arrangement, and activity of cells. In metazoans, most morphogenetic programs that establish the recognizable body plan of any given species are initiated during the developmental period, although i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e5c4063d35689d566d1fad86ddf59a4
https://doi.org/10.1007/s13752-013-0117-z

An ancient role for nuclear β-catenin in the evolution of axial polarity and germ layer segregation

Autor: Melanie Hong, Kevin Pang, Mark Q. Martindale, Patricia N. Lee, Christine A. Byrum, Joanna M. Bince, Athula H. Wikramanayake, Ronghui Xu

Publikováno v: Nature. 426:446-450

The human oncogene beta-catenin is a bifunctional protein with critical roles in both cell adhesion and transcriptional regulation in the Wnt pathway. Wnt/beta-catenin signalling has been implicated in developmental processes as diverse as elaboratio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f02d2a66ab906d87f4914023b307b29d
https://doi.org/10.1038/nature02113

A DTI-based template-free cortical connectome study of brain maturation

Autor: Etay Ziv, Donna M. Ferriero, A. James Barkovich, Olga Tymofiyeva, Christopher P. Hess, Patricia N. Lee, Duan Xu, Hannah C. Glass

Publikováno v: PloS one, vol 8, iss 5
PLoS ONE, Vol 8, Iss 5, p e63310 (2013)
Tymofiyeva, O; Hess, CP; Ziv, E; Lee, PN; Glass, HC; Ferriero, DM; et al.(2013). A DTI-Based Template-Free Cortical Connectome Study of Brain Maturation. PLoS ONE, 8(5). doi: 10.1371/journal.pone.0063310. UCSF: Retrieved from: http://www.escholarship.org/uc/item/0578j4fm
PLoS ONE

Improved understanding of how the human brain is "wired" on a macroscale may now be possible due to the emerging field of MRI connectomics. However, mapping the rapidly developing infant brain networks poses challenges. In this study, we applied an a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc2bbb75004e253179d28c9a018b75c
https://escholarship.org/uc/item/0578j4fm

The embryonic development of the Hawaiian bobtail squid (Euprymna scolopes)

Autor: Patricia N. Lee, H. Gert de Couet, Patrick Callaerts

Publikováno v: Cold Spring Harbor protocols. 2009(11)

INTRODUCTIONA staging series based on easily distinguishable morphological features is a basic and necessary tool for developmental studies. It provides a consistent reference for comparisons between independent studies, negates the need to know when

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b857bd2551919c839414dc15da0ea0
https://pubmed.ncbi.nlm.nih.gov/20150049