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pro vyhledávání: '"Patricia Muskus Veitia"'
Autor:
Daria Golosova, Daniel Brozoski, Ko-Ting Lu, Patricia Muskus Veitia, Gaurav Kumar, Curt Sigmund
Publikováno v:
Physiology. 38
Mutations in the ubiquitin ligase scaffold protein Cullin 3 (CUL3) in smooth muscle cells (SMCs) cause vascular dysfunction, arterial stiffness, and severe hypertension. We hypothesized that conditional deletion of CUL3 in SMCs causes severe hyperten
Publikováno v:
Hypertension. 79
Cullin-3 (CUL3) is a scaffold protein involved in the formation and function of the CUL3-RING E3 ubiquitin ligase complex. Loss of smooth muscle CUL3 promotes vascular dysfunction, arterial stiffness, and severe hypertension (HTN). We hypothesized th