Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Patricia Moliner"'
Autor:
Mark P. Grillo, Svetlana Markova, Marc Evanchik, Marc Trellu, Patricia Moliner, Priscilla Brun, Anne Perreard-Dumaine, Pascale Vicat, Chun Yang, James P. Driscoll, Tim J. Carlson
Publikováno v:
Xenobiotica. 51:222-238
Dilated cardiomyopathy (DCM) is a disease of the myocardium defined by left ventricular enlargement and systolic dysfunction leading to heart failure. Danicamtiv, a new targeted myosin activator de...
Autor:
Graeme C. Young, Douglas K. Spracklin, Alexander D. James, Mette G. Hvenegaard, Graeme Scarfe, David S. Wagner, Katrin Georgi, Hanno Schieferstein, Inga Bjornsdottir, Bianca van Groen, Andrea A. Romeo, Kenneth C. Cassidy, Georges Da‐violante, Bojan Bister, Stefan Blech, Ramaswamy Lyer, Simone I. Schulz, Filip Cuyckens, Patricia Moliner
Publikováno v:
Clinical pharmacology and therapeutics.
The human absorption, distribution, metabolism, and excretion (hADME) study is the cornerstone of the clinical pharmacology package for small molecule drugs, providing comprehensive information on the rates and routes of disposition and elimination o
Autor:
Mark P, Grillo, Svetlana, Markova, Marc, Evanchik, Marc, Trellu, Patricia, Moliner, Priscilla, Brun, Anne, Perreard-Dumaine, Pascale, Vicat, James P, Driscoll, Tim J, Carlson
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 51(2)
Dilated cardiomyopathy (DCM) is a disease of the myocardium defined by left ventricular enlargement and systolic dysfunction leading to heart failure. Danicamtiv, a new targeted myosin activator designed for the treatment of DCM, was characterised in
Autor:
Catherine Arabeyre-Fabre, Michele Bremond, Sandrine Salle-Lefort, Aurelie Vivares, Robert Ngo, Sylvie Klieber, Jean-François Gallas, Gérard Fabre, Geraldine Penarier, Patricia Moliner
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 45(1)
1. The quantitative prediction of the pharmacokinetic parameters of a drug from data obtained using human in vitro systems remains a significant challenge i.e. prediction of metabolic clearance in humans and estimation of the relative contribution of
Autor:
Martine Mandray, Eric Marti, Céline Ollier, Catherine Arabeyre-Fabre, Gérard Fabre, Patricia Moliner, Robert Ngo, Sylvie Klieber, Priscilla Brun
Publikováno v:
Pharmacology Research & Perspectives
The in vitro metabolism of dronedarone and its major metabolites has been studied in human liver microsomes and cryopreserved hepatocytes in primary culture through the use of specific or total cytochrome P450 (CYP) and monoamine oxidase (MAO) inhibi