Proteomics-wise, how similar are mouse and human platelets?

Autor: Patricia Martínez-Botía, Patricia Villar, Graciela Carbajo-Argüelles, Zacaria Jaiteh, Andrea Acebes-Huerta, Laura Gutiérrez

Publikováno v: Platelets, Vol 34, Iss 1 (2023)

The field of proteomics and its application to platelet biology, is rapidly and promisingly developing. Platelets (and megakaryocytes) are postulated as biosensors of health and disease, and their proteome poses as a tool to identify the specific hea

Externí odkaz: https://doaj.org/article/9503da7d20284142b891931e8da7fb2a

Atomization and Characterization of Platelet-Based Bioproducts for Their Use in Regenerative Medicine: What Does What?

Autor: Andrea Acebes-Huerta, Patricia Martínez-Botía, Graciela Carbajo-Argüelles, María Carmen Muñoz-Turrillas, Ana María Ojea-Pérez, Antonio Vazquez, Johannes Eble, Laura Gutiérrez

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f892f73a062754c3e98acd0d28f890b
https://doi.org/10.2139/ssrn.4400783

Dissecting platelet proteomics to understand the pathophysiology of immune thrombocytopenia: studies in mouse models

Autor: Patricia Martínez-Botía, Marjolein Meinders, Iris M. De Cuyper, Johannes A. Eble, John W. Semple, Laura Gutiérrez

Publikováno v: Blood advances, 6(11), 3529-3534. American Society of Hematology
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Scopus

Immune thrombocytopenia (ITP) is an autoimmune disease characterized by enhanced platelet clearance and defective platelet production. Diagnosis by exclusion and "trial-error" treatment strategies are common practice, and despite the advancement in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b49b4595fa486bc8cdcca9cd49487d5
https://pubmed.ncbi.nlm.nih.gov/35298626

Immunophenotyping and Cell Sorting of Human MKs from Human Primary Sources or Differentiated In Vitro from Hematopoietic Progenitors

Autor: Cristina Martín Martín, Ángel Bernardo, Celina Benavente Cuesta, Laura Gutierrez, Andrea Acebes-Huerta, Patricia Martínez-Botía, María del Carmen Vicente-Ayuso, Adrián R. Rodríguez

Publikováno v: Journal of Visualized Experiments.

Megakaryocyte (MK) differentiation encompasses a number of endomitotic cycles that result in a highly polyploid (reaching even >64N) and extremely large cell (40-60 µm). As opposed to the fast-increasing knowledge in megakaryopoiesis at the cell bio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0b06faf413909f5efafbe42e544534d
https://doi.org/10.3791/62569

Clinical Management of Hypertension, Inflammation and Thrombosis in Hospitalized COVID-19 Patients: Impact on Survival and Concerns

Autor: Carmen Palomo-Antequera, Blanca Leoz, Ángel Bernardo, Patricia Martínez-Botía, Inmaculada Soto, Laura Gutierrez, Andrea Acebes-Huerta, Daniel Martínez-Carballeira, Alberto Caro

Publikováno v: Journal of Clinical Medicine
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
Journal of Clinical Medicine, Vol 10, Iss 1073, p 1073 (2021)
Volume 10
Issue 5

The most severe clinical manifestations of the Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are due to an unbalanced immune response and a pro-thrombotic hemostatic disturbance, with art

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6c4dbb2939e86e0f926566026085b5
http://hdl.handle.net/10651/59025