Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Patricia Madara"'
Autor:
Mark J. Cowan, Xiu-li Huang, Tong Wu, James H. Shelhamer, Xianglan Yao, Patricia Madara, Sura Alsaaty, Carolea Logun, Rafał Pawliczak
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1680:145-157
Human cytosolic phospholipase A2-alpha (cPLA2-alpha) is a critical enzyme in the liberation of arachidonic acid (AA) from cellular membranes and the subsequent formation of prostaglandins (PGs), leukotrienes (LTs), hydroxyeicosatetraenoic acids (HETE
Autor:
Mark J. Cowan, Xianglan Yao, James H. Shelhamer, Sura Alsaaty, Xiu-li Huang, Patricia Madara, Rafał Pawliczak
Publikováno v:
Gene. 310:133-142
p11 is expressed in many different cell types, and serves a variety of regulatory functions. In order to better understand the transcriptional control of this protein, the 5' promoter region of the human p11 gene was cloned and sequenced. After confi
Autor:
Xiu-li Huang, Michael J. Holtzman, Rafał Pawliczak, Mark T. Gladwin, Carolea Logun, Patricia Madara, Michael J. Walter, James H. Shelhamer, Mark J. Cowan, Xianglan Yao
Publikováno v:
Journal of Biological Chemistry. 278:9298-9308
The effect of interferon (IFN)-gamma on p11 expression was studied in two human epithelial cell lines (BEAS-2B and HeLa). Treatment with IFN-gamma resulted in increased steady-state levels of p11 mRNA and protein expression, with a time-dependent and
Autor:
Uday B. Nanavaty, Xiu-li Huang, Marion G. Lawrence, Patricia Madara, James H. Shelhamer, Rafał Pawliczak
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 27:722-731
Oxidative stress is thought to be a factor influencing many inflammatory responses, including arachidonic acid (AA) release. We have studied the effect of hydrogen peroxide on AA and prostaglandin E(2) release, cytosolic phospholipase (cPLA(2)) stead
Autor:
Robert Wesley, Ana Del Pilar Cintron, Weihan Wang, Shuibang Wang, Liang Yan, Robert L. Danner, Patricia Madara
Publikováno v:
Journal of Biological Chemistry. 275:16899-16903
Reactive oxygen species can function as intracellular messengers, but linking these signaling events with specific enzymes has been difficult. Purified endothelial nitric-oxide synthase (eNOS) can generate superoxide (O(2)) under special conditions b
Autor:
Jennifer J. Barb, Anthony F. Suffredini, Robert L. Danner, James H. Shelhamer, Carolea Logun, Rafał Pawliczak, Peter J. Munson, Patricia Madara
Publikováno v:
Physiological genomics. 23(1)
Interferon gamma (IFN-gamma) plays a role in a variety of lung inflammatory responses, and corticosteroids are frequently employed as a treatment in these conditions. Therefore, the effect of IFN-gamma, of the corticosteroid dexamethasone (Dex), or o
Autor:
Marek L. Kowalski, Marion G. Lawrence, James H. Shelhamer, Carolea Logun, Tong Wu, Anetta Ptasinska, Grzegorz Woszczek, Rafał Pawliczak, Patricia Madara
Publikováno v:
The Journal of biological chemistry. 279(47)
It has been reported that interleukin-8 (IL-8) and cyclooxygenase-2 (COX-2) expression is regulated by peroxisome proliferator-activated receptor (PPAR)-gamma synthetic ligands. We have shown previously that cytosolic phospholipase A2 (cPLA2) is able
Autor:
Carolea Logun, Mark T. Gladwin, Rafał Pawliczak, Patricia Madara, Xiu-li Huang, James H. Shelhamer, Mark J. Cowan
Publikováno v:
The Journal of biological chemistry. 277(41)
p11, a member of the S-100 family of proteins, is the cellular ligand of annexin II and also interacts with the C-terminal region of cytosolic phospholipase A(2) (cPLA(2)), inhibiting cPLA(2) activity and arachidonic acid (AA) release. It has been re
Autor:
Alan L. Van Dervort, Robert L. Danner, Patricia Madara, Margaret Tropea, Robert Wesley, Christiane C. Corriveau
Publikováno v:
The Journal of infectious diseases. 177(1)
The effects of nitric oxide (NO) on human neutrophil chemotactic responses and release of interleukin (IL)-8 was studied. Neutrophils exposed to chemoattractants (IL-8, FMLP, leukotriene B4, and C5a) failed to show increases in intracellular guanosin