Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Patricia M. White"'
Autor:
Dorota Piekna-Przybylska, Daxiang Na, Jingyuan Zhang, Cameron Baker, John M. Ashton, Patricia M. White
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Externí odkaz:
https://doaj.org/article/86a2c7475c984d21bfcf2f16caa8b2a5
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-11 (2022)
Abstract The mammalian cochlea is an exceptionally well-organized epithelium composed of hair cells, supporting cells, and innervating neurons. Loss or defects in any of these cell types, particularly the specialized sensory hair cells, leads to deaf
Externí odkaz:
https://doaj.org/article/1b81a23a12c74221ade3736f8c57cfbf
Autor:
Daxiang Na, Jingyuan Zhang, Holly J. Beaulac, Dorota Piekna-Przybylska, Paige R. Nicklas, Amy E. Kiernan, Patricia M. White
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/c68b9152182e4c02a21fec004e139749
Autor:
Daxiang Na, Jingyuan Zhang, Holly J. Beaulac, Dorota Piekna-Przybylska, Paige R. Nicklas, Amy E. Kiernan, Patricia M. White
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Alzheimer’s Disease (AD) is a neurodegenerative illness without a cure. All current therapies require an accurate diagnosis and staging of AD to ensure appropriate care. Central auditory processing disorders (CAPDs) and hearing loss have been assoc
Externí odkaz:
https://doaj.org/article/47a2165efc7c4fb9af0161da79fe7763
Autor:
Dorota Piekna-Przybylska, Daxiang Na, Jingyuan Zhang, Cameron Baker, John M. Ashton, Patricia M. White
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2023)
Hearing loss caused by the death of cochlear hair cells (HCs) might be restored through regeneration from supporting cells (SCs) via dedifferentiation and proliferation, as observed in birds. In a previous report, ERBB2 activation in a subset of coch
Externí odkaz:
https://doaj.org/article/9cf99676ae704d6bab349f1edb9ddc3b
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-15 (2021)
Abstract The prevalence of noise-induced hearing loss (NIHL) continues to increase, with limited therapies available for individuals with cochlear damage. We have previously established that the transcription factor FOXO3 is necessary to preserve out
Externí odkaz:
https://doaj.org/article/036bf20c70ab4a98a1625e1321ad5514
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Noise induced hearing loss (NIHL) is a disease that affects millions of Americans. Identifying genetic pathways that influence recovery from noise exposure is an important step forward in understanding NIHL. The transcription factor Foxo3 in
Externí odkaz:
https://doaj.org/article/73b48b44d0244223aa65432907473c86
Autor:
Patricia M. White
Publikováno v:
Brain Sciences, Vol 10, Iss 10, p 756 (2020)
Most adults who acquire hearing loss find it to be a disability that is poorly corrected by current prosthetics. This gap drives current research in cochlear mechanosensory hair cell regeneration and in hearing restoration. Birds and fish can spontan
Externí odkaz:
https://doaj.org/article/945dcd9982a34775bd15f2651d357b61
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235491 (2020)
Noise-induced hearing loss (NIHL) affects millions of people worldwide and presents a large social and personal burden. Pharmacological activation of SIRT3, a regulator of the mitochondrial oxidative stress response, has a protective effect on hearin
Externí odkaz:
https://doaj.org/article/aeb7b565e66240cda485ac3412b72305
Autor:
Patricia M. White, Daxiang Na
Publikováno v:
Journal of visualized experiments : JoVE. (190)
Many reports in the last 15 years have assessed changes in the auditory brainstem response (ABR) waveform after insults such as noise exposure. Common changes include reductions in the peak 1 amplitude and the relative latencies of the later peaks, a