Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Patricia M. Rusu"'
Autor:
Samantha M. Solon-Biet, Ximonie Clark, Kim Bell-Anderson, Patricia M. Rusu, Ruth Perks, Therese Freire, Tamara Pulpitel, Alistair M. Senior, Andrew J. Hoy, Okka Aung, David G. Le Couteur, David Raubenheimer, Adam J. Rose, Arthur D. Conigrave, Stephen J. Simpson
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113536- (2023)
Summary: Fibroblast growth factor 21 (FGF21), an endocrine signal robustly increased by protein restriction independently of an animal’s energy status, exerts profound effects on feeding behavior and metabolism. Here, we demonstrate that considerin
Externí odkaz:
https://doaj.org/article/67b2b68aaa1d44e198ce08c2781e6b02
Autor:
Yann W. Yap, Patricia M. Rusu, Andrea Y. Chan, Barbara C. Fam, Andreas Jungmann, Samantha M. Solon-Biet, Christopher K. Barlow, Darren J. Creek, Cheng Huang, Ralf B. Schittenhelm, Bruce Morgan, Dieter Schmoll, Bente Kiens, Matthew D. W. Piper, Mathias Heikenwälder, Stephen J. Simpson, Stefan Bröer, Sofianos Andrikopoulos, Oliver J. Müller, Adam J. Rose
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Dietary protein dilution, where protein is reduced and replaced by other nutrient sources without caloric restriction, promotes metabolic health via the hepatokine Fgf21. Here, the authors show that essential amino acids threonine and tryptophan are
Externí odkaz:
https://doaj.org/article/36856bb21e41464a998b62244a235694
Publikováno v:
Nutrients, Vol 13, Iss 5, p 1469 (2021)
Prior studies have reported that dietary protein dilution (DPD) or amino acid dilution promotes heightened water intake (i.e., hyperdipsia) however, the exact dietary requirements and the mechanism responsible for this effect are still unknown. Here,
Externí odkaz:
https://doaj.org/article/2a21a0784891460e893398a015e43350
Autor:
Katherine Roberts-Thomson, Ludovico Maggi, Susanne Hille, Annika Zota, Yuqin Wu, Kathrin V. Schmidt, Michelle A. Keske, Yann W. Yap, Young H Lee, Thomas Sharkie, Andrea Y. Chan, Mathias Heikenwalder, Jürgen G. Okun, Andreas Jungmann, Ryan D. Russell, Stephan Herzig, Patricia M. Rusu, Oliver J. Müller, Matthias Blüher, Adam J. Rose, Jonas Schumacher
Publikováno v:
Nature metabolism. 3(3)
Both obesity and sarcopenia are frequently associated in ageing, and together may promote the progression of related conditions such as diabetes and frailty. However, little is known about the pathophysiological mechanisms underpinning this associati
Autor:
Annika Zota, Matthias Blüher, Ludovico Maggi, Susanne Hille, Oliver J. Müller, Yann W. Yap, Adam J. Rose, Young H Lee, Stephan Herzig, Kathrin V. Schmidt, Mathias Heikenwalder, Jürgen G. Okun, Andreas Jungmann, Andrea Y. Chan, Patricia M. Rusu, Jonas Schumacher, Thomas Sharkie
Both obesity and sarcopenia are frequently associated in ageing, and together may promote the progression of related conditions such as diabetes and frailty. However, little is known about the pathophysiological mechanisms underpinning this associati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::492b8e07f2d20d5871f511aa3f7ea592
https://doi.org/10.1101/2020.05.25.115709
https://doi.org/10.1101/2020.05.25.115709
Autor:
Stefan Bröer, Christopher K. Barlow, Cheng Huang, Stephen J. Simpson, Darren J. Creek, Dieter Schmoll, Matthew D.W. Piper, Andrea Y. Chan, Samantha M. Solon-Biet, Bente Kiens, Oliver J. Müller, Yann W. Yap, Adam J. Rose, Barbara C Fam, Bruce A. Morgan, Mathias Heikenwalder, Andreas Jungmann, Patricia M. Rusu, Ralf B. Schittenhelm, Sofianos Andrikopoulos
Publikováno v:
Yap, Y W, Rusu, P M, Chan, A Y, Fam, B C, Jungmann, A, Solon-Biet, S M, Barlow, C K, Creek, D J, Huang, C, Schittenhelm, R B, Morgan, B, Schmoll, D, Kiens, B, Piper, M D W, Heikenwälder, M, Simpson, S J, Bröer, S, Andrikopoulos, S, Müller, O J & Rose, A J 2020, ' Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution ', Nature Communications, vol. 11, no. 1, 2894 . https://doi.org/10.1038/s41467-020-16568-z
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Dietary protein dilution (DPD) promotes metabolic-remodelling and -health but the precise nutritional components driving this response remain elusive. Here, by mimicking amino acid (AA) supply from a casein-based diet, we demonstrate that restriction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::294484612c08d31e43d4f4a8d0080aa1
https://curis.ku.dk/portal/da/publications/restriction-of-essential-amino-acids-dictates-the-systemic-metabolic-response-to-dietary-protein-dilution(e8d27972-1dda-47ed-b3fe-10a2460ee39b).html
https://curis.ku.dk/portal/da/publications/restriction-of-essential-amino-acids-dictates-the-systemic-metabolic-response-to-dietary-protein-dilution(e8d27972-1dda-47ed-b3fe-10a2460ee39b).html
Autor:
Barbara C. Fam, Christopher K. Barlow, Patricia M. Rusu, Samantha M. Solon-Biet, Cheng Huang, Dieter Schmoll, Stefan Bröer, Bruce A. Morgan, Matthew D.W. Piper, Andreas Jungmann, Ralf B. Schittenhelm, Mathias Heikenwalder, Darren J. Creek, Adam J. Rose, Stephen J. Simpson, Andrea Y. Chan, Oliver J. Müller, Bente Kiens, Yann W. Yap, Sofianos Andrikopoulos
Dietary protein dilution (DPD) promotes metabolic remodelling and health but the precise nutritional components driving this response remain elusive. Here we demonstrate that dietary amino acids (AA) are sufficient and necessary to drive the response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7b6bcb9e61e03d8c3db9b39d411858
Publikováno v:
Nutrients, Vol 13, Iss 1469, p 1469 (2021)
Nutrients
Nutrients
Prior studies have reported that dietary protein dilution (DPD) or amino acid dilution promotes heightened water intake (i.e., hyperdipsia) however, the exact dietary requirements and the mechanism responsible for this effect are still unknown. Here,
Autor:
Bernd Bukau, Gözde Bekki, Barbara Costa, Kristina Döring, Te Guo, Prasad Phapale, Günter Kramer, Darjus F. Tschaharganeh, Steffen Dettling, Bernhard Radlwimmer, Anna Neuerburg, Hai-Kun Liu, Chunxuan Shao, Magdalena Schlotter, Peng Zou, Yonghe Wu, Mathias Heikenwalder, Huiqin Körkel-Qu, Christel Herold-Mende, Patricia M. Rusu, Tchirupura S. Shankar, Olga Friesen, Azer Aylin Acikgöz, Peter Angel
Publikováno v:
Cell Stem Cell
Brain tumor stem cells (BTSCs) are a chemoresistant population that can drive tumor growth and relapse, but the lack of BTSC-specific markers prevents selective targeting that spares resident stem cells. Through a ribosome-profiling analysis of mouse
Autor:
Adam J. Rose, Oliver J. Müller, Mathias Heikenwalder, Patricia M. Rusu, Jürgen G. Okun, Stephan Herzig, Jonas Schumacher, Mattias Blüher, Yann Yap
Publikováno v:
Obesity Research & Clinical Practice. 13:254