Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Patricia M. Okamoto"'
Autor:
Sabrina A. Gardner, Katelyn S. Weymouth, Wei S. Kelly, Ekaterina Bogdanova, Wenjie Chen, Daniel Lupu, Joshua Suhl, Qiandong Zeng, Ute Geigenmüller, Debbie Boles, Patricia M. Okamoto, Geraldine McDowell, Melissa A. Hayden, Narasimhan Nagan
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 16, Iss 1, Pp 1-10 (2018)
Abstract Background Extensive clinical and genetic heterogeneity of inherited cancers has allowed multi-gene panel testing to become an efficient means for identification of patients with an inherited predisposition to a broad spectrum of syndromic a
Externí odkaz:
https://doaj.org/article/ce4dfad6377e4430a37f157d75ea052f
Autor:
Lynne S Rosenblum, Stanley Letovsky, Patricia M. Okamoto, Ruth A Heim, Qiandong Zeng, Natalia T Leach, Jean A Smith, Zhaoqing Zhou, Angela Kenyon, Hui Zhu, Marcia Eisenberg
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Next-generation sequencing (NGS) is widely used in genetic testing for the highly sensitive detection of single nucleotide changes and small insertions or deletions. However, detection and phasing of structural variants, especially in repetitive or h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e3c7d4ad05005f4a092711c51f8354
http://europepmc.org/articles/PMC7490669
http://europepmc.org/articles/PMC7490669
Autor:
Patricia M. Okamoto, Diana W. Bianchi, Lillian M. Zwemer, Marcia Eisenberg, Sarah L. Nolin, Heather C. Wick
Publikováno v:
Prenatal Diagnosis. 37:43-52
Objective We tested the hypothesis that FMR1 expansions would result in global gene dysregulation as early as the second trimester of human fetal development. Method Using cell-free fetal RNA obtained from amniotic fluid supernatant and expression mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0e6daea6ecf50f7b80089d3422941af
https://doi.org/10.1002/pd.4928
https://doi.org/10.1002/pd.4928
Autor:
Patricia M. Okamoto, Ute Geigenmüller, Narasimhan Nagan, Joshua Suhl, Melissa A. Hayden, Ekaterina Bogdanova, Wenjie Chen, Daniel S. Lupu, Katelyn S. Weymouth, Qiandong Zeng, Debbie Boles, Wei S. Kelly, Geraldine McDowell, Sabrina A. Gardner
Publikováno v:
Hereditary Cancer in Clinical Practice
Hereditary Cancer in Clinical Practice, Vol 16, Iss 1, Pp 1-10 (2018)
Hereditary Cancer in Clinical Practice, Vol 16, Iss 1, Pp 1-10 (2018)
Background Extensive clinical and genetic heterogeneity of inherited cancers has allowed multi-gene panel testing to become an efficient means for identification of patients with an inherited predisposition to a broad spectrum of syndromic and nonsyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64acfe538fb1afbe84832560bfd0cb06
https://doi.org/10.1186/s13053-017-0083-8
https://doi.org/10.1186/s13053-017-0083-8
Autor:
Lillian M, Zwemer, Sarah L, Nolin, Patricia M, Okamoto, Marcia, Eisenberg, Heather C, Wick, Diana W, Bianchi
Publikováno v:
Prenatal diagnosis. 37(1)
We tested the hypothesis that FMR1 expansions would result in global gene dysregulation as early as the second trimester of human fetal development.Using cell-free fetal RNA obtained from amniotic fluid supernatant and expression microarrays, we comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27b8843be6da6513febdb91a19991551
https://pubmed.ncbi.nlm.nih.gov/27646161
https://pubmed.ncbi.nlm.nih.gov/27646161
Publikováno v:
Journal of Biological Chemistry. 274:10277-10286
Dynamin, a 100-kDa GTPase, has been implicated to be involved in synaptic vesicle recycling, receptor-mediated endocytosis, and other membrane sorting processes. Dynamin self-assembles into helical collars around the necks of coated pits and other me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4f8309f8707e4481ae06ecb8675af8
https://doi.org/10.1074/jbc.274.15.10277
https://doi.org/10.1074/jbc.274.15.10277
Autor:
Patricia M. Okamoto, George A. Marzluf
Publikováno v:
Molecular and General Genetics MGG. 240:221-230
The enzyme nitrate reductase, which catalyzes the reduction of nitrate to nitrite, is a multi-redox center homodimeric protein. Each polypeptide subunit is approximately 100 kDa in size and contains three separate domains, one each for a flavin, a he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7116ea9375414e1161b28c79ec87438a
https://doi.org/10.1007/bf00277060
https://doi.org/10.1007/bf00277060
Autor:
Richard B. Vallee, Alan D. Marmorstein, Patricia M. Okamoto, Geri Kreitzer, Enrique Rodriguez-Boulan
Publikováno v:
Nature cell biology. 2(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06b75d197d715ae4d3c4578770ba531
https://pubmed.ncbi.nlm.nih.gov/10655593
https://pubmed.ncbi.nlm.nih.gov/10655593
Publikováno v:
The Journal of biological chemistry. 272(17)
The GTPase dynamin has been implicated in the regulation of the scission of coated and noncoated pits during the early stages of endocytosis. Various macromolecules including microtubules, acidic phospholipids, and Src homology 3 (SH3) domains have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b304d456e6f2c05090635c185d5100
https://pubmed.ncbi.nlm.nih.gov/9111080
https://pubmed.ncbi.nlm.nih.gov/9111080
Autor:
Richard B. Vallee, Patricia M. Okamoto
Publikováno v:
Trends in cell biology. 5(2)
Dynamin is a large GTPase implicated in controlling the initial stages of endocytosis. Its mechanism of action remains uncertain, but it is expected to interact cyclically with components of the endocytic machinery. Dynamin binds to a number of diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81e4de250becbc855c09fbd58e35e3b
https://pubmed.ncbi.nlm.nih.gov/14731403
https://pubmed.ncbi.nlm.nih.gov/14731403