Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Patricia M. Mulrooney-Cousins"'
Autor:
Christopher P. Corkum, Louisa L. Wiede, Cara L.-A. Ruble, Jiabin Qiu, Patricia M. Mulrooney-Cousins, Meredith A. Steeves, David E. Watson, Tomasz I. Michalak
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Woodchuck (Marmota monax) infected with woodchuck hepatitis virus (WHV) is the most pathogenically compatible naturally occurring model of human hepatitis B virus (HBV) infection, chronic hepatitis B, and HBV-induced hepatocellular carcinoma. This sy
Externí odkaz:
https://doaj.org/article/3540bc6b9c5b47518ad3a62312db74a3
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Since the discovery of hepatitis B virus (HBV) over five decades ago, there have been many independent studies showing presence of HBV genomes in cells of the immune system. However, the nature of HBV lymphotropism and its significance with respect t
Externí odkaz:
https://doaj.org/article/c0f7c33d4f53464fbc0d2bf94d9cd2ec
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Woodchucks infected with woodchuck hepatitis virus (WHV) represent a highly valuable model of human hepatitis B virus (HBV) infection, chronic hepatitis (CH), and virus induced-primary liver cancer. Toll-like receptors (TLRs) are important mediators
Externí odkaz:
https://doaj.org/article/e41c4cefccb84b8490f22033677f39d6
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology, Vol 12 (2021)
Since the discovery of hepatitis B virus (HBV) over five decades ago, there have been many independent studies showing presence of HBV genomes in cells of the immune system. However, the nature of HBV lymphotropism and its significance with respect t
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 9 (2018)
Frontiers in Microbiology, Vol 9 (2018)
Woodchucks infected with woodchuck hepatitis virus (WHV) represent a highly valuable model of human hepatitis B virus (HBV) infection, chronic hepatitis (CH), and virus induced-primary liver cancer. Toll-like receptors (TLRs) are important mediators
Publikováno v:
Journal of Clinical and Translational Hepatology
Woodchuck hepatitis virus (WHV) is molecularly and pathogenically closely related to hepatitis B virus (HBV). Both viruses display tropism towards hepatocytes and cells of the immune system and cause similar liver pathology, where acute hepatitis can
Publikováno v:
Journal of Virology. 87:1035-1048
Exposure to multiple small doses of hepatitis B virus (HBV) is a frequent occurrence in high-risk groups, including close relatives of infected individuals, primary care givers, and intravenous drug users. It remains uncertain whether such repeated c
Autor:
John P. Roberts, Carla S. Coffin, Patricia M. Mulrooney-Cousins, Guido van Marle, Norah A. Terrault, Tomasz I. Michalak
Publikováno v:
Liver Transplantation. 17:955-962
The characterization of hepatitis B virus (HBV) quasispecies in different compartments in liver transplant (LT) recipients may be helpful in optimizing prophylaxis regimens. The aims of this study were to evaluate liver, peripheral blood mononuclear
Autor:
Norah A. Terrault, John P. Roberts, Tomasz I. Michalak, Patricia M. Mulrooney-Cousins, Carla S. Coffin, G. van Marle, Marion G. Peters
Publikováno v:
Journal of Viral Hepatitis. 18:415-423
The hepatitis B virus (HBV) replicates via an error-prone reverse transcriptase generating potential drug-resistant quasispecies. The degree of HBV variability in liver vs peripheral blood mononuclear cells (PBMC) in patients on long-term suppressive
Publikováno v:
Journal of Virology. 82:7540-7550
Woodchuck hepatitis virus (WHV), which is closely related to human hepatitis B virus, infects the liver but also invariably establishes persistent infection in the lymphatic system. Although the dose of invading virus appears to be the main factor in