Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Patricia M. Deegan"'
Publikováno v:
Toxicology. 106:159-166
The ability of atrial natriuretic peptide (ANP) to prevent cisplatin-induced nephrotoxicity was compared to the protective effect of 3% NaCl. ANP (1 microgram/kg/min), 3% NaCl or peptide buffer vehicle (50 microliters/min) were infused for 45 min to
Publikováno v:
Renal Failure. 17:117-123
The ability of a 13 amino-acid analog of atrial natriuretic peptide (ANP), A68828, to prevent development of cisplatin toxicity was evaluated in a rat model. ANP (1 microgram/kg/min), A68828 (10 micrograms/kg/min), A68828 (50 micrograms/kg/min), or p
Autor:
Michael P. Ryan, Patricia M. Deegan, Cearuil Nolan, Mark M. Jones, Mark A. Basinger, K. R. Hande
Publikováno v:
Renal failure. 17(6)
The role of the renin-angiotensin system (RAS) in the pathogenesis of cisplatin nephrotoxicity was evaluated in an experimental rat model using a specific, nonpeptide angiotensin II(AII) receptor blocker, losartan. Rats were treated with a single dos
Publikováno v:
Toxicology. 89(1)
When cisplatin is administered in the form of a cisplatin-methionine substitution complex, high doses of cisplatin can be tolerated with no obvious signs of renal toxicity. We have demonstrated that male Wistar rats receiving a single i.p. dose of ci