Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Patricia Müsch"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 846 (2024)
Current drug development tends towards complex chemical molecules, referred to as “beyond rule of five” (bRo5) compounds, which often exhibit challenging physicochemical properties. Measuring Caco-2 permeability of those compounds is difficult du
Externí odkaz:
https://doaj.org/article/a94c5963141f476788baf6d1cae2be35
Autor:
Dong Ye, Álvaro López Mármol, Verena Lenz, Patricia Muschong, Anita Wilhelm-Alkubaisi, Manuel Weinheimer, Mirko Koziolek, Kerstin A. Sauer, Loic Laplanche, Mario Mezler
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 699 (2022)
The poor solubility and permeability of compounds beyond Lipinski’s Rule of Five (bRo5) are major challenges for cell-based permeability assays. Due to their incompatibility with gastrointestinal components in biorelevant media, the exploration of
Externí odkaz:
https://doaj.org/article/735fe606651748828518a48a13532d69
Autor:
Dirk Woitalla, Siegfried Muhlack, Sandra Konietzka, Thomas Müller, Patricia Müsch, Horst Przuntek
Publikováno v:
Pharmaceutics
Pharmaceutics; Volume 2; Issue 3; Pages: 313-320
Pharmaceutics; Volume 2; Issue 3; Pages: 313-320
Application of oral fast release amantadine and levodopa may induce an improvement of motor symptoms in patients with Parkinson’s disease (PD). The objective of this trial was to investigate the clinical efficacy of a fast release amantadine sulfat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c2c698ead95103da9097964fdb89cde
https://doi.org/10.3390/pharmaceutics2030313
https://doi.org/10.3390/pharmaceutics2030313