Unlocking Therapeutic Synergy: Tailoring Drugs for Comorbidities such as Depression and Diabetes through Identical Molecular Targets in Different Cell Types

Autor: Thierry Coppola, Guillaume Daziano, Ilona Legroux, Sophie Béraud-Dufour, Nicolas Blondeau, Patricia Lebrun

Publikováno v: Cells, Vol 12, Iss 23, p 2768 (2023)

Research in the field of pharmacology aims to generate new treatments for pathologies. Nowadays, there are an increased number of chronic disorders that severely and durably handicap many patients. Among the most widespread pathologies, obesity, whic

Externí odkaz: https://doaj.org/article/70a557f00c384720b63c425ad556abff

Genetic diversity in Brazilian tall coconut populations by microsatellite markers

Autor: Francisco Elias Ribeiro, Luc Baudouin, Patricia Lebrun, Lázaro José Chaves, Claudio Brondani, Emiliano Fernandes Nassau Costa, Roland Vencovsky

Publikováno v: Crop Breeding and Applied Biotechnology, Vol 13, Iss 4, Pp 356-362 (2013)

The tall coconut palm was introduced in Brazil in 1553, originating from the island of Cape Verde. The aim of the presentstudy was to evaluate the genetic diversity of ten populations of Brazilian tall coconut by 13 microsatellite markers. Samples we

Externí odkaz: https://doaj.org/article/60e471ebebc944fa8ecd6346ba45cdc7

microRNA-375 regulates glucose metabolism-related signaling for insulin secretion

Autor: Marc Prentki, Christophe Duranton, Virginie Casamento, N Gautier, François Pattou, Charlotte Hinault, Michel Tauc, Gaia Fabris, Emmanuel Van Obberghen, Didier F. Pisani, Patricia Lebrun, Julie Kerr-Conte, Stéphane Dalle, Olivier Dumortier

Publikováno v: Journal of Endocrinology
Journal of Endocrinology, BioScientifica, 2020, 244 (1), pp.189-200. ⟨10.1530/JOE-19-0180⟩
Journal of Endocrinology, 2020, 244 (1), pp.189-200. ⟨10.1530/JOE-19-0180⟩

Enhanced beta cell glycolytic and oxidative metabolism are necessary for glucose-induced insulin secretion. While several microRNAs modulate beta cell homeostasis, miR-375 stands out as it is highly expressed in beta cells where it regulates beta cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ceada618742fd35d78696ad13973877
https://hal.archives-ouvertes.fr/hal-02400345

Sortilin in Glucose Homeostasis: From Accessory Protein to Key Player?

Autor: Sophie Béraud-Dufour, Patricia Lebrun, Nicolas Blondeau, Céline Hivelin, Thierry Coppola

Publikováno v: Frontiers in Pharmacology, Vol 9 (2019)
Frontiers in Pharmacology
Frontiers in Pharmacology, Frontiers, 2019, 9, ⟨10.3389/fphar.2018.01561⟩

International audience; The pharmacological properties and physiological roles of the type I receptor sortilin, also called neurotensin receptor-3, are various and complex. Sortilin is involved in important biological functions from neurotensin and p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4558c697db5ee6c15646d9e7eb3fa82
https://www.frontiersin.org/article/10.3389/fphar.2018.01561/full

Genetic diversity in Brazilian tall coconut populations by microsatellite markers

Autor: Roland Vencovsky, Luc Baudouin, Claudio Brondani, E. F. N. Costa, Patricia Lebrun, Francisco Elias Ribeiro, Lázaro José Chaves

Publikováno v: Crop Breeding and Applied Biotechnology, Vol 13, Iss 4, Pp 356-362 (2013)
Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA-Alice)
Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
Crop Breeding and Applied Biotechnology
Crop Breeding and Applied Biotechnology v.13 n.4 2013
Sociedade Brasileira de Melhoramento de Plantas
instacron:CBAB
Crop Breeding and Applied Biotechnology, Volume: 13, Issue: 4, Pages: 356-362, Published: DEC 2013

The tall coconut palm was introduced in Brazil in 1553, originating from the island of Cape Verde. The aim of the present study was to evaluate the genetic diversity of ten populations of Brazilian tall coconut by 13 microsatellite markers. Samples w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ea42b4e6ce73f26246c7dbb4286ef1
http://www.sbmp.org.br/cbab/siscbab/uploads/bd531da5-a777-7f66.pdf