Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Patricia Lanzano"'
Autor:
Emily Breidbart, MD, Lauren Golden, MD, Claudia Gonzaga-Jauregui, PhD, Liyong Deng, MD, Patricia Lanzano, BA, Charles LeDuc, PhD, JianCheng Guo, MD, PhD, John D. Overton, PhD, Jeffery Reid, PhD, Alan Shuldiner, MD, Wendy K. Chung, MD, PhD
Publikováno v:
AACE Clinical Case Reports, Vol 4, Iss 5, Pp e411-e414 (2018)
ABSTRACT: Objective: To present a case of adult-onset familial diabetes mellitus in which a genetic etiology typical for neonatal diabetes was identified.Methods: We conducted whole-exome and Sanger sequencing, assessed clinical presentation and fami
Externí odkaz:
https://doaj.org/article/931e4b2fa6ff491b856e88e674076187
Autor:
Xiao Fan, Wendy K. Chung, Emily Breidbart, Rudolph L. Leibel, Jiancheng Guo, Patricia Lanzano, Charles A. LeDuc, Liyong Deng
Publikováno v:
J Pediatr Endocrinol Metab
Objectives There have been few large-scale studies utilizing exome sequencing for genetically undiagnosed maturity onset diabetes of the young (MODY), a monogenic form of diabetes that is under-recognized. We describe a cohort of 160 individuals with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc780e6b488e21cf2fc0f021ecc0e9b2
https://doi.org/10.1515/jpem-2020-0501
https://doi.org/10.1515/jpem-2020-0501
Autor:
John D. Overton, Jiancheng Guo, Patricia Lanzano, Emily Breidbart, Lauren Golden, Jeffery Reid, Charles A. LeDuc, Alan R. Shuldiner, Claudia Gonzaga-Jauregui, Wendy K. Chung, Liyong Deng
Publikováno v:
AACE Clinical Case Reports, Vol 4, Iss 5, Pp e411-e414 (2018)
Objective: To present a case of adult-onset familial diabetes mellitus in which a genetic etiology typical for neonatal diabetes was identified.Methods: We conducted whole-exome and Sanger sequencing, assessed clinical presentation and family history
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06442d43336b1bd665e0fe098fb3d7f0
https://doi.org/10.4158/accr-2018-0007
https://doi.org/10.4158/accr-2018-0007
Autor:
Jian-min Liu, Patricia Lanzano, Thomas L. Nickolas, Zhenyan He, Na Luo, Rudolph L. Leibel, Lori M. Zeltser, Kevin W. Williams, Ioanna Mosialou, Liyong Deng, Steven Shikhel, Wendy K. Chung, Stavroula Kousteni, Mishaela R. Rubin, Jeffrey E. Pessin, Richard A. Friedman, Yiru Huang, Jonathan Barasch, Haihong Zong, Antonio Maurizi
Publikováno v:
Nature. 546(7658)
Bone has recently emerged as a pleiotropic endocrine organ that secretes at least two hormones, FGF23 and osteocalcin, which regulate kidney function and glucose homeostasis, respectively. These findings have raised the question of whether other bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98f3d0742f0ef56f3b8933bc9c0e525
https://pubmed.ncbi.nlm.nih.gov/28273060
https://pubmed.ncbi.nlm.nih.gov/28273060
Autor:
Jonathan Barasch, Ioanna Mosialou, Liyong Deng, Steven Shikhel, Haihong Zong, Wendy K. Chung, Thomas Nicholas, Antonio Maurizi, Jeffrey E. Pessin, Lori M. Zeltser, Patricia Lanzano, Stavroula Kousteni, Kevin W. Williams, Mishaela R. Rubin, Na Luo, Rudolph L. Leibel, Jian-min Liu, Yiru Huang, Richard A. Friedman, Zhenyan He
Bone has recently emerged as a pleiotropic endocrine organ that secretes at least two hormones, FGF23 and osteocalcin, which regulate kidney function and glucose homeostasis, respectively. These findings have raised the question of whether other bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5200dc2407cadcc0364621f928ffcfc
http://hdl.handle.net/11697/180280
http://hdl.handle.net/11697/180280
Autor:
Diana R. O’Day, Jayne F. Martin Carli, Wendy K. Chung, Charles A. LeDuc, Michael Rosenbaum, Rudolph L. Leibel, Liheng Wang, Dieter Egli, George Stratigopoulos, Patricia Lanzano, Dan Doherty
Publikováno v:
Cell Metabolism. 19:767-779
SummaryCommon polymorphisms in the first intron of FTO are associated with increased body weight in adults. Previous studies have suggested that a CUX1-regulatory element within the implicated FTO region controls expression of FTO and the nearby cili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2bc9c882afed400bebdb1e71bdfd910
https://doi.org/10.1016/j.cmet.2014.04.009
https://doi.org/10.1016/j.cmet.2014.04.009
Autor:
Yufeng Shen, Roja Motaghedi, Svetlana Ten, Joan C. Han, Rudolph L. Leibel, Noel K. Maclaren, Wendy K. Chung, Patricia Lanzano, Yee Him Cheung, Richard Gill, Nazrat M. Mirza, Jack A. Yanovski
Publikováno v:
Obesity. 22:576-584
Objective Obesity is a major public health problem that increases risk for a broad spectrum of co-morbid conditions. Despite evidence for a strong genetic contribution to susceptibility to obesity, previous efforts to discover the relevant genes usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b12884ec2aa83a622c698b18b1d476d
https://doi.org/10.1002/oby.20492
https://doi.org/10.1002/oby.20492
Autor:
Patricia Lanzano, Katrina Celis, Gloria H. Su, Christen J. Lennon, Maria Teresa Guerra Rendon, Sidney B. Eisig, David C. Hoffman, Henry Ostos, Wendy K. Chung, Edwin Guzman, José Arturo Pacheco Nuñez, Andrew C. Birkeland, Joseph Haddad
Publikováno v:
The Laryngoscope. 122:2082-2087
Objectives/Hypothesis: Orofacial clefts are the most common craniofacial birth defects in humans, with the majority of orofacial clefts occurring as nonsyndromic cleft lip with or without cleft palate (NSCLP). We previously demonstrated associations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a89122f79df4b11df7fee1b54271090f
https://doi.org/10.1002/lary.23394
https://doi.org/10.1002/lary.23394
Publikováno v:
Cardiology in the Young. 22:194-201
BackgroundHeterotaxy syndrome is caused by left–right asymmetry disturbances and is associated with abnormal lateralisation of the abdominal and thoracic organs. The heart is frequently involved and the severity of the abnormality usually determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1bff4e919b0ec8eb35edbc155d06c8
https://doi.org/10.1017/s1047951111001181
https://doi.org/10.1017/s1047951111001181
Autor:
Megan C. MacDougall, Harry R. Kissileff, Wendy K. Chung, Joo Lee Song, Kathleen L. Keller, Patricia Lanzano, Hope Cassano, Adrienne Reid, Liyong Deng
Publikováno v:
Obesity. 18:1194-1200
Previous studies have shown that inherited taste blindness to bitter compounds like 6-n-propylthiouracil (PROP) may be a risk factor for obesity, but this literature has been highly controversial. The objectives of this study were (i) to confirm find
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d87b5d7e685fede70d44bd21bee6f95f
https://doi.org/10.1038/oby.2009.306
https://doi.org/10.1038/oby.2009.306