Výsledky vyhledávání - "Patricia L. Reilly"

Autor: Patricia L. Reilly

Publikováno v: The Expanding Discourse ISBN: 9780429492839

This chapter investigates the figures of gender employed both to praise and to deprecate color, and their effects on the way color was subsequently perceived and written out in the Renaissance. The relationship between disegno and colore as one of ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b4939d4d175c3770cbcd6dd31efb5006
https://doi.org/10.4324/9780429492839-5

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An orally active, primate selective antagonist of LFA-1 inhibits delayed-type hypersensitivity in a humanized-mouse model

Autor: Sudha Desai, Patricia L. Reilly, Deborah D. Jeanfavre, Gerald Nabozny, Terence A. Kelly, Lemieux Rene M, Maret Panzenbeck

Publikováno v: European Journal of Pharmacology. 534:233-240

Compound I, a novel small molecule antagonist (Kd=6 nM) of human lymphocyte function-associated antigen-1 (LFA-1, CD11a/CD18) was tested for activity in a humanized mouse model of delayed-type hypersensitivity (trans vivo delayed-type hypersensitivit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1749fd551f64ce34e2ef8ba2e12717f1
https://doi.org/10.1016/j.ejphar.2006.01.004

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Partners in Science: A Model Cooperative Program Introducing High School Teachers and Students to Leading-Edge Pharmaceutical Science

Autor: Patricia L. Reilly, Joseph R. Woska, Danielle M. Collins, Brian J. Canney, Erin L. Arcario

Publikováno v: Journal of Science Education and Technology. 14:409-414

Partners in Science is a cooperative program between Boehringer Ingelheim Pharmaceuticals, Inc. and area high schools in the community surrounding our Connecticut campus. It is a two-phase program that introduces high school students and teachers to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ca8243debe772f053e696070bc841ac
https://doi.org/10.1007/s10956-005-8085-0

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Artists’ workshops

Autor: Patricia L. Reilly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02a2ca74a0be2f7a68a92cfb3000c6e7
https://doi.org/10.1017/cco9781139034067.008

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Effect of deoxycoformycin and Val-boroPro on the associated catalytic activities of lymphocyte CD26 and ecto-adenosine deaminase

Autor: Patricia L. Reilly, Charles Kennedy, Joseph R. Woska, Barbara-Jean Bormann, Christopher Pargellis, Jay Prendergast, Deborah D. Jeanfavre, Carol Stearns, Randall W. Barton

Publikováno v: Biochemical Pharmacology. 52:1757-1765

CD26 and ecto-adenosine deaminase (ADA) are found associated on the plasma membrane of T lymphocytes and each possess distinct catalytic activities. CD26 has a proteolytic activity identical to dipep-tidylpeptidase IV (DPPIV; E.C. 3.4.14.5), and ecto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e21fb6bb0700ce826e7f390569d276
https://doi.org/10.1016/s0006-2952(96)00597-7

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Second-generation lymphocyte function-associated antigen-1 inhibitors: 1H-imidazo[1,2-alpha]imidazol-2-one derivatives

Publikováno v: Journal of medicinal chemistry. 47(22)

A novel class of lymphocyte function-associated antigen-1 (LFA-1) inhibitors is described. Discovered during the process to improve the physicochemical and metabolic properties of BIRT377 (1, Figure 1), a previously reported hydantoin-based LFA-1 inh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe9a79e4c0fcd3c81b9d9548fd038228
https://pubmed.ncbi.nlm.nih.gov/15481974

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Small molecule LFA-1 antagonists compete with an anti-LFA-1 monoclonal antibody for binding to the CD11a I domain: development of a flow-cytometry-based receptor occupancy assay

Autor: Robert Rothlein, Maret Panzenbeck, Elizabeth Mainolfi, Terence A. Kelly, Rachel R. Kroe, Gary O. Caviness, Kathleen Last-Barney, Joseph R. Woska, Deborah D. Jeanfavre, Patricia Giblin, Steven E. Fogal, Patricia L. Reilly, Takashi Kei Kishimoto

Publikováno v: Journal of immunological methods. 277(1-2)

The beta(2) integrin LFA-1 (CD11a/CD18) is a leukocyte-specific adhesion molecule that mediates leukocyte extravasation, antigen presentation, and T-cell-mediated cytolysis through its interaction with its counter-receptors, ICAM-1, ICAM-2, and ICAM-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142e86ff3ea13b2e8037e20a330cce80
https://pubmed.ncbi.nlm.nih.gov/12799043

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The role of leukocyte function-associated antigen-1 in animal models of inflammation

Autor: Stephen E. Fogal, Patricia L. Reilly, Nancy Haynes, Raymond J. Winquist, Gerald Nabozny, Sudha Desai, Maret Panzenbeck, Donald Souza

Publikováno v: European journal of pharmacology. 429(1-3)

Both preclinical and clinical data have identified leukocyte function-associated antigen-1 (LFA-1) as an important component of inflammatory disease states. We evaluated small molecule inhibitors of this glycoprotein in several animal models in which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c725ee9262a0518a414364f4995a4bb
https://pubmed.ncbi.nlm.nih.gov/11698049

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