Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Patricia L, Bruno"'
Publikováno v:
Developmental medicine and child neurologyREFERENCES.
This study reports on the long-term results for an initial cohort of patients with Sunflower syndrome who enrolled in an open-label study of low-dose fenfluramine as well as the short-term results of a second cohort.We conducted a single-center, open
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a324cea83860d3a57334b65a4864c7cf
https://pubmed.ncbi.nlm.nih.gov/36562419
https://pubmed.ncbi.nlm.nih.gov/36562419
Autor:
Lauren A. Skirvin, Elizabeth A. Thiele, Reid A. Grinspoon, Bradley M. Fleming, Sandip Patel, Christina Wade, Emma Wolper, Patricia L. Bruno
Publikováno v:
Epilepsia. 62:1594-1603
OBJECTIVE Cannabidiol (CBD) has been shown to reduce seizures among patients with refractory epilepsies of various etiologies in recent clinical trials and an expanded access program (EAP). Most studies report efficacy over short time periods (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9119a3ce80fd59d0552bce6f12c3da
https://doi.org/10.1111/epi.16936
https://doi.org/10.1111/epi.16936
Autor:
Amy K. Morgan, Jo Sourbron, Elizabeth A. Thiele, Samarth P. Doshi, Sandip Patel, Patricia L. Bruno, Uyen Vu, Kennedy R. Geenen, Amy Falk
Publikováno v:
Developmental medicine and child neurologyReferences. 63(12)
AIM To determine the efficacy of fenfluramine on seizure frequency in patients with Sunflower syndrome. Secondary endpoints were changes in electroencephalogram (EEG) characteristics, cognitive functioning, executive functioning, and quality of life.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd8d6349db02d145c83b39df979ea37
https://pubmed.ncbi.nlm.nih.gov/34216017
https://pubmed.ncbi.nlm.nih.gov/34216017
Autor:
James R. Barnett, Jason H. Freedman, Jo Sourbron, Bradley M. Fleming, Patricia L. Bruno, Kennedy R. Geenen, Elizabeth A. Thiele
Publikováno v:
Epileptic disorders : international epilepsy journal with videotape. 22(3)
To characterize the clinical phenotype of Sunflower syndrome. Sunflower syndrome is a rare photosensitive epilepsy syndrome characterized by highly stereotyped seizures, photosensitivity, and heliotropism. We retrospectively reviewed the medical reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d0f67f2929836ee637b80e03dca60d
https://pubmed.ncbi.nlm.nih.gov/32554362
https://pubmed.ncbi.nlm.nih.gov/32554362
Autor:
Alexandra L. Geffrey, Patricia L. Bruno, James R. Barnett, Aline Herlopian, Jo Sourbron, Lauren A. Skirvin, Sarah F. Pollack, Evan J. Hess, Elizabeth A. Thiele
Publikováno v:
Epilepsybehavior : EB. 106
Objective This study aimed to evaluate clinical efficacy and safety of purified pharmaceutical cannabidiol (CBD) as an adjunctive therapy in refractory childhood-onset epileptic spasms (ES). Methods Nine patients with ES were enrolled in an Instituti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17d7efd19868414187c3a01432aa758
https://pubmed.ncbi.nlm.nih.gov/32169600
https://pubmed.ncbi.nlm.nih.gov/32169600
Efficacy of cannabidiol in subjects with refractory epilepsy relative to concomitant use of clobazam
Autor:
Jo Sourbron, Lauren A. Skirvin, Patricia L. Bruno, Taylor E. Savage, Elizabeth A. Thiele, Christina J. Anagnos, Emma Wolper
Publikováno v:
Epilepsy research. 160
Objective To evaluate the efficacy of open-label, highly purified cannabidiol (CBD, Epidiolex®) in treating refractory epilepsy relative to the concomitant use of clobazam (CLB) as well as the clinical implications of changes in CLB and norclobazam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec47afbf641b7d85c2cf548bbc363ea
https://pubmed.ncbi.nlm.nih.gov/31923763
https://pubmed.ncbi.nlm.nih.gov/31923763
Autor:
Elizabeth A. Thiele, Samarth P. Doshi, Patricia L. Bruno, Kennedy R. Geenen, Nicholas R. Ambrosio, Bradley M. Fleming, James R. Barnett, Jason H. Freedman
Publikováno v:
Epilepsy & Behavior. 117:107856
Objective To characterize the clinical phenotype, treatments, and impact on quality of life of Sunflower syndrome. Methods A 138-question survey was created focusing on seizure description, disease course, treatment history, medical history, family h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da348b6ba9f40304186989aa0f910a1d
https://doi.org/10.1016/j.yebeh.2021.107856
https://doi.org/10.1016/j.yebeh.2021.107856
Autor:
Elizabeth A. Thiele, Jan L. Paolini, Kirsten A. Moody, Evan J. Hess, Alexandra L. Geffrey, Sarah F. Pollack, Patricia L. Bruno, Lauren A. Skirvin
Publikováno v:
Epilepsia. 57:1617-1624
SummaryObjective Tuberous sclerosis complex (TSC) is an autosomal-dominant genetic disorder with highly variable expression. The most common neurologic manifestation of TSC is epilepsy, which affects approximately 85% of patients, 63% of whom develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffbe932b0f8d8224fc0bc2d600048b39
https://doi.org/10.1111/epi.13499
https://doi.org/10.1111/epi.13499
Publikováno v:
Journal of Pediatric Epilepsy. :097-101
To determine the safety, tolerability, and efficacy of rufinamide in treating refractory epilepsy in a largely pediatric population. A retrospective chart review was conducted of all patients prescribed rufinamide from December 2008 to July 2010 in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06e27e9ebc60d09e2b7725f8823e3073
https://doi.org/10.3233/pep-2012-016
https://doi.org/10.3233/pep-2012-016
Autor:
Christina J. Anagnos, Alexandra L. Geffrey, Elizabeth A. Thiele, Robin C. C. Ryther, Patricia L. Bruno, Melanie Jennesson, Ronald L. Thibert, Ali Shoeb, Anna M. Larson
Publikováno v:
Epilepsia. 53:1162-1169
Summary Purpose: Disrupted sleep patterns in children with epilepsy and their parents are commonly described clinically. A number of studies have shown increased frequency of sleep disorders among pediatric epilepsy patients; however, few have charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d104dd8d0caa35f95be8ec589334677
https://doi.org/10.1111/j.1528-1167.2012.03515.x
https://doi.org/10.1111/j.1528-1167.2012.03515.x