Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Patricia K. Russ"'
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0130260 (2015)
In this study, we integrated magnetic bead-based sample preparation and isothermal loop mediated amplification (LAMP) of TB in a single tube. Surrogate sputum samples produced by the Program for Appropriate Technology in Health containing inactivated
Externí odkaz:
https://doaj.org/article/455a5ab683654bebaa5a6c3a87041a90
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68369 (2013)
Due to the presence of PCR inhibitors, PCR cannot be used directly on most clinical samples, including human urine, without pre-treatment. A magnetic bead-based strategy is one potential method to collect biomarkers from urine samples and separate th
Externí odkaz:
https://doaj.org/article/193fab5cb32f4cd6baa8284f60ea82da
Autor:
Anna E. Wolfe, Nicholas M. Adams, Patricia K. Russ, Cassandra Wessely, Megan E. Pask, Mindy Leelawong, Kelly A. Richardson, Frederick R. Haselton, Stephanie I. Pearlman
Publikováno v:
ACS Applied Materials & Interfaces
Nucleic acid-based diagnostic tests often require isolation and concentration of nucleic acids from biological samples. Commercial purification kits are difficult to use in low-resource settings because of their cost and insufficient laboratory infra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4bcb3a49ae8ead3a590c94d9bb02ad
https://pubmed.ncbi.nlm.nih.gov/32039572
https://pubmed.ncbi.nlm.nih.gov/32039572
Autor:
Andrew B. Doyle, Anna L. Bitting, Patricia K. Russ, Francesca Solinas, David W. Wright, Aditya V. Karhade, Frederick R. Haselton
Publikováno v:
SLAS Technology. 21:590-598
PCR is the most sensitive molecular diagnostic available for infectious diseases. The goal for low-resource settings is a simple, inexpensive instrument. Toward this goal, we previously published a self-contained sample preparation instrument that us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::893d0eab54c03b62c306cb511ebdd6d7
https://doi.org/10.1177/2211068216634072
https://doi.org/10.1177/2211068216634072
Autor:
April C. Pettit, Andrew J.M. Nel, David W. Wright, Carlos Zamudio, Frederick R. Haselton, Mark L. Baglia, Megan E. Pask, Keersten M. Ricks, Keertan Dheda, Hali Bordelon, Francesca Solinas, Patricia K. Russ, Tatiana Cáceres, Philip A. Short, Jonathan Michael Blackburn
Urine samples are increasingly used for diagnosing infections including Escherichia coli, Ebola virus, and Zika virus. However, extraction and concentration of nucleic acid biomarkers from urine is necessary for many molecular detection strategies su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7c930098e0834861b260dcd4529acd
https://hdl.handle.net/20.500.12866/4631
https://hdl.handle.net/20.500.12866/4631
Autor:
Timothy J. Yeatman, Frederick R. Haselton, Min S. Chang, Baolin Zhang, Patricia K. Russ, Caitlyn W. Barrett, R. Daniel Beauchamp, Wael El-Rifai, Ashwath Jayagopal, Christopher S. Williams, Steven A. Eschrich, M. Kay Washington, Sai Han Presley, Daniel O. Rosenblatt, Dunfa Peng, Xi Chen, J. Joshua Smith, J.-L. Yang, Christopher J. Pino
Publikováno v:
Journal of Clinical Investigation. 121:4056-4069
The acquisition of a mesenchymal phenotype is a critical step in the metastatic progression of epithelial carcinomas. Adherens junctions (AJs) are required for suppressing this epithelial-mesenchymal transition (EMT) but less is known about the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a198bb74b0f88d078ee0ea2bbf2db97
https://doi.org/10.1172/jci44228
https://doi.org/10.1172/jci44228
Autor:
Hali Bordelon, Nicholas M. Adams, Amy S. Klemm, Patricia K. Russ, Frederick R. Haselton, David W. Wright, John V. Williams, H. Keipp Talbot
Publikováno v:
ACS Applied Materials & Interfaces. 3:2161-2168
Nucleic acid-based diagnostics are highly sensitive and specific, but are easily disrupted by the presence of interferents in biological samples. In a laboratory or hospital setting, the influence of these interferents can be minimized using an RNA o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567faec331156aa031f267f93acacd20
https://doi.org/10.1021/am2004009
https://doi.org/10.1021/am2004009
Publikováno v:
Analytical Biochemistry. 410:141-148
In traditional immuno-polymerase chain reaction (immuno-PCR), a single antibody recognition event is associated with one to three DNA tags, which are subsequently amplified by PCR. Here we describe a nanoparticle-amplified immuno-PCR (NPA-IPCR) assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::978a809aa81304705912493e7df7ed32
https://doi.org/10.1016/j.ab.2010.11.033
https://doi.org/10.1016/j.ab.2010.11.033
Publikováno v:
Bioconjugate Chemistry. 18:1424-1433
Quantum dot-antibody bioconjugates (QD-mAb) were synthesized incorporating PEG cross-linkers and Fc-shielding mAb fragments to increase in vivo circulation times and targeting efficiency. Microscopy of endothelial cell cultures incubated with QD-mAb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2859ab7502bcd21f04228e1d34195f
https://doi.org/10.1021/bc070020r
https://doi.org/10.1021/bc070020r
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0130260 (2015)
PLoS ONE
PLoS ONE
In this study, we integrated magnetic bead-based sample preparation and isothermal loop mediated amplification (LAMP) of TB in a single tube. Surrogate sputum samples produced by the Program for Appropriate Technology in Health containing inactivated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01bd97f028a75167957ea38c723c771
http://europepmc.org/articles/PMC4488445?pdf=render
http://europepmc.org/articles/PMC4488445?pdf=render