Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Patricia K. Padovani"'
Autor:
Foster Brown, William F. Ebling, Shaker A. Mousa, Ram Kapil, Thomas M. Reilly, Patricia K. Padovani, Henry J. Pieniaszek, Jun Yu, Jeffrey S. Barrett, Jeffrey M. Bozarth, Martha H. Corjay
Publikováno v:
Biopharmaceutics & Drug Disposition. 20:309-318
The disposition of XV459, a potent, selective GP IIb/IIIa antagonist, has been examined following intravenous administration of XP280, the benzenesulphonate salt, and 3H-SA202, the trifluroacetic acid salt, to male guinea pigs. A liquid chromatograph
Autor:
Shaker A. Mousa, Patricia K. Padovani, Ram Kapil, Check Y. Quon, Gilbert N. Lam, Thomas A. Emm
Publikováno v:
Thrombosis Research. 86:221-232
The pharmacokinetic-pharmacodynamic (PK/PD) relationship of a novel platelet glycoprotein IIb/IIIa receptor antagonist, XU063, was evaluated as a function of biological matrix in beagle dogs. The disposition of 14 C-radioactivity in various blood or
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 665:226-231
A selective and sensitive high-performance liquid chromatographic assay for a novel cognitive enhancer, X9121 (I), and its mono N-oxide metabolite, XG696 (II), in dog plasma has been developed. Compounds I, II and internal standard (I.S.) were first
Autor:
H.F. Stampfli, C.M. Banks, S.‐M. Huang, Ram Kapil, Thomas A. Emm, William Lee, Steven T. Wu, Patricia K. Padovani
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 657:254-260
A specific and sensitive HPLC assay for the determination of DMP 728 in dog and rat plasma has been developed. The method involves solid-phase extraction of DMP 728 and the internal standard from plasma using a C2 column. The extracted compounds are
Publikováno v:
Journal of chromatography. 577(2)
A sensitive and specific capillary gas chromatographic assay is reported for the quantitation of oxycodone in human plasma. The technique involves a single extraction of oxycodone and internal standard (hydrocodone) from plasma by toluene containing