Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Patricia J. Keller"'
Autor:
Jerrica L. Breindel, Adam Skibinski, Maja Sedic, Ania Wronski-Campos, Wenhui Zhou, Patricia J. Keller, Joslyn Mills, James Bradner, Tamer Onder, Charlotte Kuperwasser
Publikováno v:
Stem Cell Reports, Vol 9, Iss 3, Pp 943-955 (2017)
Organogenesis and tissue development occur through sequential stepwise processes leading to increased lineage restriction and loss of pluripotency. An exception to this appears in the adult human breast, where rare variant epithelial cells exhibit pl
Externí odkaz:
https://doaj.org/article/15112164c4b44467a40b1d0c89dc317d
Autor:
Charlotte Kuperwasser, Victoria Seewaldt, Stephen P. Naber, Dana D. Baker, Patricia J. Keller, Jessica McCready, Lisa M. Arendt
PDF file, 322K, Obesity-like stromal cells did not increase responsiveness of endothelial cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6552f63e1089be87069cfe3187cc6442
https://doi.org/10.1158/0008-5472.22396481.v1
https://doi.org/10.1158/0008-5472.22396481.v1
Autor:
Charlotte Kuperwasser, Victoria Seewaldt, Stephen P. Naber, Dana D. Baker, Patricia J. Keller, Jessica McCready, Lisa M. Arendt
PDF file, 1009K, Characterization of SVF/EV and SVF/CCL2-derived end stage tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911169632dd555cda58df829c79b53ef
https://doi.org/10.1158/0008-5472.22396478.v1
https://doi.org/10.1158/0008-5472.22396478.v1
Autor:
Charlotte Kuperwasser, Victoria Seewaldt, Stephen P. Naber, Dana D. Baker, Patricia J. Keller, Jessica McCready, Lisa M. Arendt
PDF file, 390K, Macrophage-derived CXCL12 increases angiogenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b0d3110344e84990fa849668934623
https://doi.org/10.1158/0008-5472.22396484.v1
https://doi.org/10.1158/0008-5472.22396484.v1
Autor:
Charlotte Kuperwasser, Victoria Seewaldt, Stephen P. Naber, Dana D. Baker, Patricia J. Keller, Jessica McCready, Lisa M. Arendt
PDF file, 945K, Adipose stromal cells synthesize lipid droplets in response to adipogenic media.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5dd36bc0a4091ed5a644966903e192
https://doi.org/10.1158/0008-5472.22396490.v1
https://doi.org/10.1158/0008-5472.22396490.v1
Autor:
Charlotte Kuperwasser, Victoria Seewaldt, Stephen P. Naber, Dana D. Baker, Patricia J. Keller, Jessica McCready, Lisa M. Arendt
PDF file, 93K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6d4864f217bb3531aaef2f4b5b86eb
https://doi.org/10.1158/0008-5472.22396475
https://doi.org/10.1158/0008-5472.22396475
Autor:
Charlotte Kuperwasser, Victoria Seewaldt, Stephen P. Naber, Dana D. Baker, Patricia J. Keller, Jessica McCready, Lisa M. Arendt
PDF file, 102K, Description of additional methods and procedures used in the study. Also includes supplemental references.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a839c716ed847c9f0157463af7c8dd21
https://doi.org/10.1158/0008-5472.22396472.v1
https://doi.org/10.1158/0008-5472.22396472.v1
Autor:
Gozde Colak, Vikas Gupta, Andrea Patriarca, John Mascarenhas, Patricia J. Keller, James Shao, Claire N. Harrison, Nikki Granacher, Gary J. Schiller, Tim C. P. Somervaille, Moshe Talpaz, Jonathan Lambert, Katarina Luptakova, Srdan Verstovsek, Raajit Rampai, Ronald Hoffman, Linda Foltz, Prithviraj Bose, Marina Kremyanskaya, Alessandro M. Vannucchi, Witold Prejzner, Mark Drummond
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 21:S361-S362
Context: Pelabresib (CPI-0610), a first-in-class, oral, small-molecule inhibitor of BET proteins, has the potential to promote disease-modifying activity through altered gene regulation of key oncogenic, fibrotic, and inflammatory factors in MF. Many
Autor:
Jing Wang, Oksana Zavidij, Srdan Verstovsek, Horatiu Olteanu, Dong Chen, Patrick Trojer, Patricia J. Keller, Claire N. Harrison, Moshe Talpaz, Katarina Luptakova, Gozde Colak, April Chiu, Mohamed E. Salama, Jike Cui, Curtis A. Hanson, Raajit Rampai, John Mascarenhas, Alessandro M. Vannucchi, Ruben A. Mesa, Zehua Chen, Stephen T. Oh, Jennifer A. Mertz, Jeffrey S. Humphrey
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 21:S363-S364
Context: Pelabresib (CPI-0610) is a potent, selective BET bromodomain inhibitor under investigation in the ongoing Phase 2 MANIFEST trial, given as monotherapy to ruxolitinib (rux)-intolerant/refractory myelofibrosis (MF) pts in arm 1, as an “add-o
Autor:
Patrick Trojer, Patricia J. Keller, Moshe Talpaz, April Chiu, Srdan Verstovsek, Pietro Taverna, Sergey Efuni, Claire N. Harrison, Natalia Curto-Garcia, Curtis A. Hanson, Dong Chen, Mohamed E. Salama, Raajit K. Rampal, Zehua Chen, Stephen T. Oh, John Mascarenhas, Gozde Colak, Horatiu Olteanu, Alessandro M. Vannucchi, Ruben A. Mesa, Jike Cui, Oksana Zavidij
Publikováno v:
Blood. 138:2568-2568
Background: Myelofibrosis (MF) is characterized by progressive bone marrow (BM) fibrosis resulting from aberrant megakaryopoiesis and expression of pro-inflammatory cytokines. These processes, heavily influenced by bromodomain and extraterminal domai