Výsledky vyhledávání - "Patricia I. Porto"

Peroxisome proliferator-activated receptor gamma and its coactivator-1 alpha may be associated with features of the metabolic syndrome in adolescents

Autor: Silvia Cristina Sookoian, Patricia I. Porto, Carlos José Pirola, Silvia García, Claudio Gonzalez, Guillermo Dieuzeide

Publikováno v: Journal of Molecular Endocrinology. 35:373-380

Our objective was to search for differences in genotypes of peroxisome proliferator-activated receptor gamma (PPARγ) (Pro12 Ala) and its coactivator PGC-1α (Gly482 Ser) in adolescents harboring features of metabolic syndrome. In a population-based

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd5b818513e05ef0cb78379b4e20153
https://doi.org/10.1677/jme.1.01837

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Thyrotropin-Releasing Hormone Receptor (TRHR) Gene Is Associated With Essential Hypertension

Autor: Maria Silvina Landa, Patricia I. Porto, Silvia I. García, Carlos José Pirola, Tobias Kirszner, Guillermo Dieuzeide, Claudio Gonzalez, Yanquel Plotquin

Publikováno v: Scopus-Elsevier

Abstract — — In essential hypertension, a polygenic and multifactorial syndrome, several genes interact with the environment to produce high blood pressure. Thyrotropin-releasing hormone (TRH) plays an important role in central cardiovascular reg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6bae0b1dffca6dca23e21ed9a862f0
https://doi.org/10.1161/01.hyp.38.3.683

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Antisense Inhibition of Thyrotropin-Releasing Hormone Reduces Arterial Blood Pressure in Spontaneously Hypertensive Rats

Autor: Victoria M. Garfunkel, Carlos José Pirola, Sammuel Finkielman, Patricia I. Porto, Azucena L. Alvarez, Silvia I. García

Publikováno v: Hypertension. 37:365-370

Thyrotropin-releasing hormone (TRH) plays an important role in central cardiovascular regulation. Recently, we described that the TRH precursor gene overexpression induces hypertension in the normal rat. In addition, we published that spontaneously h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29be0e00bb1d069846915f8f492607e1
https://doi.org/10.1161/01.hyp.37.2.365

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Central Overexpression of the TRH Precursor Gene Induces Hypertension in Rats

Autor: Azucena L. Alvarez, Patricia I. Porto, Samuel Finkielman, Veronica N. Martinez, Carlos José Pirola, Silvia I. García, Daniela Shaurli

Publikováno v: Hypertension. 30:759-766

Abstract Extrahypothalamic TRH participates in cardiovascular regulation and spontaneous hypertension of the rat. To investigate whether an increase in central TRH activity produces hypertension we studied the effect of the preTRH overproduction indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695f87348026a1cedd611a72a1859fe0
https://doi.org/10.1161/01.hyp.30.3.759

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Clinical features of the metabolic syndrome in adolescents: minor role of the Trp64Arg beta3-adrenergic receptor gene variant

Autor: Maria Silvina Landa, Guillermo Dieuzeide, Claudio González, Patricia I. Porto, Silvia I. García, Carlos José Pirola

Publikováno v: Pediatric research. 55(5)

Obesity and hypertension are increasing medical problems in adolescents. We evaluated the association between being overweight-particularly abdominal fat-and having hypertension and assessed the contribution of the Trp64Arg beta3-adrenergic receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b997900aa754fc52eb2af84142288b
https://pubmed.ncbi.nlm.nih.gov/14739355

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Renin-angiotensin-aldosterone system loci and multilocus interactions in young-onset essential hypertension

Autor: Patricia I. Porto, Silvia I. García, Carlos José Pirola, Guillermo Dieuzeide, Claudio Gonzalez

Publikováno v: Clinical and experimental hypertension (New York, N.Y. : 1993). 25(2)

Renin-angiotensin-aldosterone system component genes have been associated to essential hypertension. Thus, we studied the association of singe locus or multilocus interactions with young-onset essential hypertension.This is a case-control study based

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e05556d7da432bfba4442cdb465cfdd
https://pubmed.ncbi.nlm.nih.gov/12611423

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Thyrotropin-releasing hormone decreases leptin and mediates the leptin-induced pressor effect

Autor: Samuel Finkielman, Maria Silvina Landa, Mariano Luis Schuman, Patricia I. Porto, Carlos José Pirola, Azucena L. Alvarez, Silvia I. García

Publikováno v: Hypertension (Dallas, Tex. : 1979). 39(2 Pt 2)

Abstract— Leptin, an adipocyte-released hormone, modifies food intake and energy expenditure regulating hypothalamic-pituitary-thyroid axis function. We previously reported that thyrotropin-releasing hormone (TRH) precursor gene overexpression indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af42c0281d768586f212ff70fb43d326
https://pubmed.ncbi.nlm.nih.gov/11882596

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Expression of TRH and TRH-like peptides in a human glioblastoma-astrocytoma cell line (U-373-MG)

Autor: Silvia García, Patricia I. Porto, Azucena L. Alvarez, V.N. Martinez, Carlos José Pirola, Samuel Finkielman

Publikováno v: The Journal of endocrinology. 166(3)

The human glioblastoma-astrocytoma cell line U-373-MG shows morphological features typical of its neuroectodermal origin. Cells showed positive immunostaining for the glial fibrillary acidic protein. We used this cell culture for studying the putativ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8991d93f5b4d005ce1047d1c298d9fdb
https://pubmed.ncbi.nlm.nih.gov/10974663

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