Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Patricia I. Oteiza"'
Publikováno v:
Redox Biology, Vol 76, Iss , Pp 103359- (2024)
Intestinal permeabilization is central to the pathophysiology of chronic gut inflammation. This study investigated the efficacy of glucoraphanin (GR), prevalent in cruciferous vegetables, particularly broccoli, and its derivative sulforaphane (SF), i
Externí odkaz:
https://doaj.org/article/2f48ec8ae531492691e1b62632bd3e11
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103275- (2024)
Diet is of major importance in modulating intestinal inflammation, as the gastrointestinal tract is directly exposed to high concentrations of dietary components. Procyanidins are flavan-3-ol oligomers abundant in fruits and vegetables. Although with
Externí odkaz:
https://doaj.org/article/e96fca0f9d404fe1a32340f1804ee4e2
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102927- (2023)
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOXs) are enzymes that generate superoxide anion (O2•-) and hydrogen peroxide (H2O2), and that are widely distributed in mammalian tissues. Many bioactives, especially plant (poly)phenol
Externí odkaz:
https://doaj.org/article/faaf33e8a7e84da7a3ee8e480ef16ac5
Autor:
Wei Zhu, Patricia I. Oteiza
Publikováno v:
Redox Biology, Vol 65, Iss , Pp 102827- (2023)
Colorectal cancer (CRC) is prevalent worldwide. Dietary consumption of procyanidins has been linked to a reduced risk of developing CRC. The epidermal growth factor (EGF) receptor (EGFR) signaling pathway is frequently dysregulated in CRC. Our earlie
Externí odkaz:
https://doaj.org/article/445d31f1edae41dab4c19025badc838a
Autor:
Eleonora Cremonini, Elena Daveri, Dario E. Iglesias, Jiye Kang, Ziwei Wang, Russell Gray, Angela Mastaloudis, Colin D. Kay, Shelly N. Hester, Steven M. Wood, Cesar G. Fraga, Patricia I. Oteiza
Publikováno v:
Redox Biology, Vol 51, Iss , Pp 102273- (2022)
This study investigated the effects of supplementation with a cyanidin- and delphinidin-rich extract (CDRE) on the postprandial dysmetabolism, inflammation, and redox and insulin signaling, triggered by the consumption of a high fat meal (HFM) in hea
Externí odkaz:
https://doaj.org/article/a5fcebbeff264704ad3f6b1fd7b1c45c
Autor:
Suangsuda Supasai, Ana M. Adamo, Patricia Mathieu, Regina C. Marino, Adelaide C. Hellmers, Eleonora Cremonini, Patricia I. Oteiza
Publikováno v:
Redox Biology, Vol 44, Iss , Pp 102017- (2021)
We previously showed that zinc (Zn) deficiency affects the STAT3 signaling pathway in part through redox-regulated mechanisms. Given that STAT3 is central to the process of astrogliogenesis, this study investigated the consequences of maternal margin
Externí odkaz:
https://doaj.org/article/6fa08e223f0d429796f49ec1a8a7a5bc
Publikováno v:
Redox Biology, Vol 42, Iss , Pp 101914- (2021)
Identification of the links among flavonoid consumption, mitigation of oxidative stress and improvement of disease in humans has significantly advanced in the last decades. This review used (−)-epicatechin (EC) as an example of dietary flavonoids,
Externí odkaz:
https://doaj.org/article/ff182f1daf7946b39e1931a2ddb08ad9
Publikováno v:
Redox Biology, Vol 38, Iss , Pp 101830- (2021)
Dietary proanthocyanidins (PAC) consumption is associated with a decreased risk for colorectal cancer (CRC). Dysregulation of the epidermal growth factor (EGF) receptor (EGFR) signaling pathway is frequent in human cancers, including CRC. We previous
Externí odkaz:
https://doaj.org/article/fbc254ac0c9e4026a2aeb3b78eb9334c
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
Secondary bile acids promote gastrointestinal (GI) tract permeabilization both in vivo and in vitro. Consumption of high fat diets increases bile acid levels in the GI tract which can contribute to intestinal permeabilization and consequent local and
Externí odkaz:
https://doaj.org/article/e2d1a8d7a256458b97dd247806153730
Autor:
Elena Daveri, Eleonora Cremonini, Angela Mastaloudis, Shelly N. Hester, Steven M. Wood, Andrew L. Waterhouse, Mauri Anderson, Cesar G. Fraga, Patricia I. Oteiza
Publikováno v:
Redox Biology, Vol 18, Iss , Pp 16-24 (2018)
Consumption of diets high in fat and/or fructose content promotes tissue inflammation, oxidative stress, and insulin resistance, activating signals (e.g. NF-κB/JNK) that downregulate the insulin cascade. Current evidence supports the concept that se
Externí odkaz:
https://doaj.org/article/b93d158185a24c7a906af107ef474072