Výsledky vyhledávání - "Patricia I. Oteiza"

Akademický článek

Changes in redox network expression during Caco-2 cell differentiation into enterocytes

Autor: Wei Zhu, Eleonora Cremonini, Patricia I Oteiza

Publikováno v: Redox Experimental Medicine, Vol 2024, Iss 1, Pp 1-11 (2024)

Objective: This work characterized fluctuations in cell components involved in the regulation of cell redox homeostasis during Caco-2 cell differentiation into enterocytes. Methods: Caco-2 cells were differentiated for 10 days. Gene expression of NAD

Externí odkaz: https://doaj.org/article/569a2294041a406c9635187d60955db7

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Akademický článek

Glucoraphanin and sulforaphane mitigate TNFα-induced Caco-2 monolayers permeabilization and inflammation

Autor: Wei Zhu, Eleonora Cremonini, Angela Mastaloudis, Patricia I. Oteiza

Publikováno v: Redox Biology, Vol 76, Iss , Pp 103359- (2024)

Intestinal permeabilization is central to the pathophysiology of chronic gut inflammation. This study investigated the efficacy of glucoraphanin (GR), prevalent in cruciferous vegetables, particularly broccoli, and its derivative sulforaphane (SF), i

Externí odkaz: https://doaj.org/article/2f48ec8ae531492691e1b62632bd3e11

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Akademický článek

Structure-dependent capacity of procyanidin dimers to inhibit inflammation-induced barrier dysfunction in a cell model of intestinal epithelium

Autor: Wei Zhu, Le Xiong, Patricia I. Oteiza

Publikováno v: Redox Biology, Vol 75, Iss , Pp 103275- (2024)

Diet is of major importance in modulating intestinal inflammation, as the gastrointestinal tract is directly exposed to high concentrations of dietary components. Procyanidins are flavan-3-ol oligomers abundant in fruits and vegetables. Although with

Externí odkaz: https://doaj.org/article/e96fca0f9d404fe1a32340f1804ee4e2

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Akademický článek

(Poly)phenols and the regulation of NADPH oxidases

Autor: Cesar G. Fraga, Patricia I. Oteiza, Ezequiel J. Hid, Monica Galleano

Publikováno v: Redox Biology, Vol 67, Iss , Pp 102927- (2023)

Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOXs) are enzymes that generate superoxide anion (O2•-) and hydrogen peroxide (H2O2), and that are widely distributed in mammalian tissues. Many bioactives, especially plant (poly)phenol

Externí odkaz: https://doaj.org/article/faaf33e8a7e84da7a3ee8e480ef16ac5

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Akademický článek

NADPH oxidase 1: A target in the capacity of dimeric ECG and EGCG procyanidins to inhibit colorectal cancer cell invasion

Autor: Wei Zhu, Patricia I. Oteiza

Publikováno v: Redox Biology, Vol 65, Iss , Pp 102827- (2023)

Colorectal cancer (CRC) is prevalent worldwide. Dietary consumption of procyanidins has been linked to a reduced risk of developing CRC. The epidermal growth factor (EGF) receptor (EGFR) signaling pathway is frequently dysregulated in CRC. Our earlie

Externí odkaz: https://doaj.org/article/445d31f1edae41dab4c19025badc838a

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Akademický článek

A randomized placebo-controlled cross-over study on the effects of anthocyanins on inflammatory and metabolic responses to a high-fat meal in healthy subjects

Autor: Eleonora Cremonini, Elena Daveri, Dario E. Iglesias, Jiye Kang, Ziwei Wang, Russell Gray, Angela Mastaloudis, Colin D. Kay, Shelly N. Hester, Steven M. Wood, Cesar G. Fraga, Patricia I. Oteiza

Publikováno v: Redox Biology, Vol 51, Iss , Pp 102273- (2022)

This study investigated the effects of supplementation with a cyanidin- and delphinidin-rich extract (CDRE) on the postprandial dysmetabolism, inflammation, and redox and insulin signaling, triggered by the consumption of a high fat meal (HFM) in hea

Externí odkaz: https://doaj.org/article/a5fcebbeff264704ad3f6b1fd7b1c45c

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Akademický článek

Gestational zinc deficiency impairs brain astrogliogenesis in rats through multistep alterations of the JAK/STAT3 signaling pathway

Autor: Suangsuda Supasai, Ana M. Adamo, Patricia Mathieu, Regina C. Marino, Adelaide C. Hellmers, Eleonora Cremonini, Patricia I. Oteiza

Publikováno v: Redox Biology, Vol 44, Iss , Pp 102017- (2021)

We previously showed that zinc (Zn) deficiency affects the STAT3 signaling pathway in part through redox-regulated mechanisms. Given that STAT3 is central to the process of astrogliogenesis, this study investigated the consequences of maternal margin

Externí odkaz: https://doaj.org/article/6fa08e223f0d429796f49ec1a8a7a5bc

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Akademický článek

Linking biomarkers of oxidative stress and disease with flavonoid consumption: From experimental models to humans

Autor: Patricia I. Oteiza, Cesar G. Fraga, Monica Galleano

Publikováno v: Redox Biology, Vol 42, Iss , Pp 101914- (2021)

Identification of the links among flavonoid consumption, mitigation of oxidative stress and improvement of disease in humans has significantly advanced in the last decades. This review used (−)-epicatechin (EC) as an example of dietary flavonoids,

Externí odkaz: https://doaj.org/article/ff182f1daf7946b39e1931a2ddb08ad9

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Akademický článek

Hexameric procyanidins inhibit colorectal cancer cell growth through both redox and non-redox regulation of the epidermal growth factor signaling pathway

Autor: Elena Daveri, Ana M. Adamo, Eugenia Alfine, Wei Zhu, Patricia I. Oteiza

Publikováno v: Redox Biology, Vol 38, Iss , Pp 101830- (2021)

Dietary proanthocyanidins (PAC) consumption is associated with a decreased risk for colorectal cancer (CRC). Dysregulation of the epidermal growth factor (EGF) receptor (EGFR) signaling pathway is frequent in human cancers, including CRC. We previous

Externí odkaz: https://doaj.org/article/fbc254ac0c9e4026a2aeb3b78eb9334c

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