Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Patricia Gonzalez-DeWhitt"'
Autor:
Theresa A. Day, David L. McKinzie, Patricia Gonzalez-DeWhitt, Francis David Tingley, Ronald B. DeMattos, David R. Riddell, Dustin J. Mergott, Nicholas C. Reising, Mansuo L. Hayashi, Justin T. Hole
Publikováno v:
Alzheimer's & Dementia. 14
Autor:
Jon A. Erickson, Lianshen Zhang, Marian Mosior, Jose Alfredo Martin, Mccarthy James R, Sheila P. Little, Xiyun Chai, Jingdan Hu, Wayne David Kohn, Shu-Hui Chen, John P. Mayer, Ana B. Bueno, Patrick C. May, Mcclure Don B, Leonard N. Boggs, Hsiu-Chiung Yang, Wu-Kuang Yeh, Patricia Gonzalez-DeWhitt
Publikováno v:
Journal of Neurochemistry. 91:1249-1259
β-amyloid peptides (Aβ) are produced by a sequential cleavage of amyloid precursor protein (APP) by β- and γ-secretases. The lack of Aβ production in beta-APP cleaving enzyme (BACE1)–/– mice suggests that BACE1 is the principal β-secretase
Autor:
John E. Hale, Binhui Ni, Baolin Li, Steven M. Paul, Patricia Gonzalez-DeWhitt, Xin Wu, Yuan Su, John W. Ryder, Yan Zhou, Patrick C. May, Feng Liu, Valentina Gelfanova
Publikováno v:
Science. 302:1215-1217
A subset of nonsteroidal anti-inflammatory drugs (NSAIDs) has been shown to preferentially reduce the secretion of the highly amyloidogenic, 42-residue amyloid-β peptide Aβ 42 . We found that Rho and its effector, Rho-associated kinase, preferentia
Publikováno v:
Alzheimer's & Dementia. 8
Publikováno v:
Alzheimer's & Dementia. 8
Publikováno v:
Alzheimer's & Dementia. 8
Autor:
Amy M. Ford, Anja Köster, Josef G. Heuer, John E. Hale, Derek D. Yang, Patricia Gonzalez-DeWhitt, Yubin Qiu, Y. Bernice Chao, Christopher C. Fraser, De-Shan Li, Marian Mosior, S. Richard Jaskunas, Patrick I. Eacho
Publikováno v:
Endocrinology. 146(11)
Lipoprotein lipase (LPL) is a key regulator of triglyceride clearance. Its coordinated regulation during feeding and fasting is critical for maintaining lipid homeostasis and energy supply. Angiopoietin-like (Angptl)3 and Angptl4 are secreted protein
Autor:
Patrick C. May, Patricia Gonzalez-DeWhitt, Baolin Li, Binhui Ni, Feng Liu, Yan Zhou, Yuan Su, John W. Ryder
Publikováno v:
FEBS letters. 547(1-3)
The phosphorylation status of amyloid precursor protein (APP) at Thr668 is suggested to play a critical role in the proteolytic cleavage of APP, which generates either soluble APP(beta) (sAPP(beta)) and beta-amyloid peptide (Abeta), the major compone
Autor:
Wu-Kuang Yeh, Patricia Gonzalez-DeWhitt, Mcclure Don B, Sheila P. Little, Hsiu-Chiung Yang, Patrick J. C. May, Yuan Tu, Marian Mosior, Raymond Patch
Publikováno v:
Neurobiology of Aging. 25:S525